Adenosine mediated desensitization of cAMP signaling enhances T-cell responses

European Journal of Immunology

Volumn 40, Issue 2, 2010, Pages 449-459

  Yang, Ailian ^a   Mucsi, Ashley D ^a   Desrosiers, Melanie D ^a   Chen, Jiang Fan ^b   Schnermann, Jürgen B ^c   Blackburn, Michael R ^d   Shi, Yan ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Adjuvants; Immune regulation; T cells

Indexed keywords

5 (N ETHYLCARBOXAMIDO) ADENOSINE; ADENOSINE; ADENOSINE DERIVATIVE; ADENOSINE RECEPTOR; CD3 ANTIGEN; CYCLIC AMP; INTERLEUKIN 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DESENSITIZATION; IMMUNOREGULATION; IMMUNOSTIMULATION; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ADENOSINE; ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYCLIC AMP; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPLEEN; T-LYMPHOCYTES; XANTHINES;

EID: 75149170605     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200939586     Document Type: Article

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