High molecular weight gingipains from porphyromonas gingivalis induce cytokine responses from human macrophage-like cells via a nonproteolytic mechanism

Journal of Innate Immunity

Volumn 1, Issue 2, 2009, Pages 109-117

  Fitzpatrick, Rebecca E ^a,b   Aprico, Andrea ^a,b   Wijeyewickrema, Lakshmi C ^a,b   Pagel, Charles N ^c   Wong, David M ^a,c   Potempa, Jan ^d   MacKie, Eleanor J ^c   Pike, Robert N ^a,b  

^a Cooperative Research Centre for Oral Health Sciences ^*  (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Cytokines; Gingipains; Macrophages; Periodontal disease; Porphyromonas gingivalis; Protease

Indexed keywords

ADHESIN; ARGININE; BACTERIAL ENZYME; COMPLEMENTARY DNA; GAMMA INTERFERON; GINGIPAIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; LYSINE; PROTEIN HRGPA; PROTEIN KGP; PROTEIN RGPB; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; ARGINGIPAIN, PORPHYROMONAS GINGIVALIS; CYSTEINE PROTEINASE; CYTOKINE;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA MICROARRAY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MACROPHAGE; MOLECULAR WEIGHT; PERIODONTAL DISEASE; POLYMERASE CHAIN REACTION; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; UPREGULATION; BACTEROIDACEAE INFECTION; BIOSYNTHESIS; CELL LINE; ENZYMOLOGY; IMMUNOLOGY; INNATE IMMUNITY; MICROBIOLOGY; PHYSIOLOGY; PROTEIN SUBUNIT;

ADHESINS, BACTERIAL; BACTEROIDACEAE INFECTIONS; CELL LINE; CYSTEINE ENDOPEPTIDASES; CYTOKINES; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMMUNITY, INNATE; INTERFERON-GAMMA; INTERLEUKIN-1BETA; MACROPHAGES; PORPHYROMONAS GINGIVALIS; PROTEIN SUBUNITS; UP-REGULATION;

EID: 75149168105     PISSN: 1662811X     EISSN: 16628128     Source Type: Journal    
DOI: 10.1159/000181145     Document Type: Article

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