Gingipains, the major cysteine proteinases and virulence factors of Porphyromonas gingivalis: Structure, function and assembly of multidomain protein complexes

Current Protein and Peptide Science

Volumn 4, Issue 6, 2003, Pages 397-407

  Potempa, Jan ^a,b   Sroka, Aneta ^a   Imamura, Takahisa ^c   Travis, James ^b  

^a JAGIELLONIAN UNIVERSITY   (Poland)

^b UNIVERSITY OF GEORGIA   (United States)

^c KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Cysteine proteinase; Gingipain; Post translational modification; Processing; Proteolytic activity; Virulence; Zymogen activation

Indexed keywords

ADHESIN; CARBOXYPEPTIDASE; CASPASE; CLOSTRIPAIN; CYSTEINE PROTEINASE; ENZYME PRECURSOR; GENE PRODUCT; GINGIPAIN; GINGIPAIN K; GINGIPAIN R; GLYCAN; HEMAGGLUTININ; LEGUMAIN; LIPOPOLYSACCHARIDE; PEPTIDASE; PROTEIN PRECURSOR; SEPARASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL MEMBRANE; CELL SURFACE; COMPLEX FORMATION; CYTOPLASM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME GLYCOSYLATION; ENZYME RELEASE; ENZYME STRUCTURE; ENZYME SYNTHESIS; GENETIC CODE; HUMAN; MOLECULAR EVOLUTION; NONHUMAN; PERIODONTAL DISEASE; PORPHYROMONAS GINGIVALIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN TRANSPORT; REVIEW; STRUCTURAL HOMOLOGY;

ADHESINS, BACTERIAL; CYSTEINE ENDOPEPTIDASES; ENZYME ACTIVATION; HEMAGGLUTININS; PORPHYROMONAS GINGIVALIS; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); PORPHYROMONAS; PORPHYROMONAS GINGIVALIS;

EID: 0344825092     PISSN: 13892037     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389203033487036     Document Type: Review

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