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Volumn 46, Issue 4, 2010, Pages 640-642

Copper-catalysed bromoalkynylation of arynes

Author keywords

[No Author keywords available]

Indexed keywords

(ALKYNYL)BROMOARENE DERIVATIVE; ARYNE DERIVATIVE; BROMINE; BROMOALKYNE DERIVATIVE; COPPER; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; UNCLASSIFIED DRUG;

EID: 75149135224     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b919301d     Document Type: Article
Times cited : (52)

References (57)
  • 48
    • 28944446242 scopus 로고    scopus 로고
    • For a review on insertion reactions of arynes into element-element σ-bonds, see:
    • For a review on insertion reactions of arynes into element-element σ-bonds, see: H. Yoshida K. Tanino J. Ohshita A. Kunai Chem. Commun. 2005 5678
    • (2005) Chem. Commun. , pp. 5678
    • Yoshida, H.1    Tanino, K.2    Ohshita, J.3    Kunai, A.4
  • 49
    • 33746281785 scopus 로고    scopus 로고
    • We have already reported copper-catalysed 2:1 coupling reaction of arynes with alkynes:
    • We have already reported copper-catalysed 2:1 coupling reaction of arynes with alkynes: D. Peña D. Pérez E. Guitián Angew. Chem., Int. Ed. 2006 45 3579
    • (2006) Angew. Chem., Int. Ed. , vol.45 , pp. 3579
    • Peña, D.1    Pérez, D.2    Guitián, E.3
  • 54
    • 75149114479 scopus 로고    scopus 로고
    • note
    • Cuprous bromide was the catalyst of choice in the reaction of 7. A referee suggested that another catalytic cycle, which involves oxidative addition of 7 to cuprous bromide and subsequent insertion of benzyne, is possibly operative in this case
  • 55
    • 75149138199 scopus 로고    scopus 로고
    • note
    • The reaction of (E)-cinnamyl bromide also gave 1:1 coupling products as minor components in 24% yield. A 1:1 coupling product of benzyne with propargyl bromide was detected by MS, however, we could not pursue the exact yield, since the isolation of the product was found to be difficult. (Figure presented)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.