Differential expression of notch family members in astrocytomas and medulloblastomas

Pathology and Oncology Research

Volumn 15, Issue 4, 2009, Pages 703-710

  Xu, Peng ^a   Yu, Shizhu ^b   Jiang, Rongcai ^a   Kang, Chunsheng ^a   Wang, Guangxiu ^a   Jiang, Hao ^c   Pu, Peiyu ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b Tianjin Neurological Institute   (China)

^c HENRY FORD HOSPITAL   (United States)

Author keywords

Astrocytomas; Differential expression; Medulloblastomas; Notch family members

Indexed keywords

NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR;

ARTICLE; ASTROCYTOMA; CANCER GRADING; CANCER STAGING; CARCINOGENESIS; CELL MATURATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MEDULLOBLASTOMA; PROTEIN EXPRESSION; WESTERN BLOTTING;

ASTROCYTOMA; BRAIN NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MEDULLOBLASTOMA; PROTO-ONCOGENE PROTEINS; RECEPTOR, NOTCH1; RECEPTOR, NOTCH2; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 75049085498     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12253-009-9173-x     Document Type: Article

References (37)

1. K Mizutani K Yoon L Dang, et al. 2007 Differential Notch signalling distinguishes neural stem cells from intermediate progenitors Nature 449 351 355 10.1038/nature06090 1:CAS:528:DC%2BD2sXhtVKiu7nM 17721509 (Pubitemid 47443472)
2. UM Fiúza AM Arias 2007 Cell and molecular biology of Notch J Endocrinol 194 459 474 10.1677/JOE-07-0242 17761886 (Pubitemid 47471215)
3. J Yochem K Weston I Greenwald 1988 The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch Nature 335 547 550 10.1038/335547a0 1:CAS:528:DyaL1MXktVWku7w%3D 3419531
4. OY Lubman SV Korolev R Kopan 2004 Anchoring notch genetics and biochemistry; structural analysis of the ankyrin domain sheds light on existing data Mol Cell 13 619 626 10.1016/S1097-2765(04)00120-0 1:CAS:528: DC%2BD2cXis1Kktbo%3D 15023333 (Pubitemid 38368120)
5. RJ Fleming 1998 Structural conservation of Notch receptors and ligands Semin Cell Dev Biol 9 599 607 10.1006/scdb.1998.0260 1:CAS:528: DyaK1MXhs12ns70%3D 9918871
6. KG Leong A Karsan 2006 Recent insights into the role of Notch signaling in tumorigenesis Blood 107 2223 2233 10.1182/blood-2005-08-3329 1:CAS:528:DC%2BD28XisFOjt7s%3D 16291593 (Pubitemid 43345539)
7. T Iso L Kedes Y Hamamori 2003 HES and HERP Families: multiple effectors of the Notch signaling pathway J Cell Physiol 194 237 255 10.1002/jcp.10208 1:CAS:528:DC%2BD3sXhtFKiurs%3D 12548545 (Pubitemid 36176887)
8. J Lasky H Wu 2005 Notch signaling, brain development, and human disease Pediatr Res 57 104R 109R 10.1203/01.PDR.0000159632.70510.3D 15817497
9. L Miele 2006 Notch signaling Clin Cancer Res 12 1074 1079 10.1158/1078-0432.CCR-05-2570 1:CAS:528:DC%2BD28XhsFaltrY%3D 16489059 (Pubitemid 43342494)
10. RA Kovall 2008 More complicated than it looks: assembly of Notch pathway transcription complexes Oncogene 27 5099 5109 10.1038/onc.2008.223 1:CAS:528:DC%2BD1cXhtVGgtLbF 18758478
11. EM Hansson U Lendahl G Chapman 2004 Notch signaling in development and disease Semin Cancer Biol 14 320 328 10.1016/j.semcancer.2004.04.011 1:CAS:528:DC%2BD2cXmt1Khsb8%3D 15288257 (Pubitemid 38993633)
12. S Artavanis-Tsakonas MD Rand RJ Lake 1999 Notch signaling: cell fate control and signal integration in development Science 284 770 776 10.1126/science.284.5415.770 1:CAS:528:DyaK1MXivVKrs7Y%3D 10221902 (Pubitemid 29291335)
13. AP Weng Y Nam MS Wolfe, et al. 2003 Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling Mol Cell Biol. 23 655 664 10.1128/MCB.23.2.655-664.2003 1:CAS:528:DC%2BD3sXjslajsA%3D%3D 12509463 (Pubitemid 36050558)
14. S Weijzen P Rizzo M Braid, et al. 2002 Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells Nat Med 8 979 986 10.1038/nm754 1:CAS:528:DC%2BD38Xms1ait7Y%3D 12185362 (Pubitemid 35033702)
15. P Zagouras S Stifani CM Blaumueller, et al. 1995 Alterations in Notch signaling in neoplastic lesions of the human cervix Proc Natl Acad Sci U S A 92 6414 6418 10.1073/pnas.92.14.6414 1:CAS:528:DyaK2MXmslKqur8%3D 7604005
16. M Nicolas A Wolfer K Raj, et al. 2003 Notch1 functions as a tumor suppressor in mouse skin Nat Genet 33 416 421 10.1038/ng1099 1:CAS:528:DC%2BD3sXhsV2kurs%3D 12590261 (Pubitemid 36278861)
17. GP Dotto 2008 Notch tumor suppressor function Oncogene 27 5115 5123 10.1038/onc.2008.225 1:CAS:528:DC%2BD1cXhtVGgtLfP 18758480
18. MZ Qiu PY Pu CS Kang, et al. 2008 The inhibitory effect of siRNA targeting Notch1 on the U251 glioblastoma cell growth in vivo Chin J Microsurg 31 214 215
19. X Fan I Mikolaenko I Elhassan, et al. 2004 Notchl and notch2 have opposite effects on embryonal brain tumor growth Cancer Res 64 7787 7793 10.1158/0008-5472.CAN-04-1446 1:CAS:528:DC%2BD2cXptFemu70%3D 15520184 (Pubitemid 39446911)
20. Y Miyamoto A Maitra B Ghosh, et al. 2003 Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis Cancer Cell 3 565 576 10.1016/S1535-6108(03)00140-5 1:CAS:528:DC%2BD3sXltlSmsLw%3D 12842085 (Pubitemid 36808651)
21. BJ Nickoloff BA Osborne L Miele 2003 Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents Oncogene 22 6598 6608 10.1038/sj.onc.1206758 1:CAS:528: DC%2BD3sXnsl2rsro%3D 14528285
22. R Callahan SE Egan 2004 Notch signaling in mammary development and oncogenesis J Mammary Gland Biol Neoplasia 9 145 163 10.1023/B:JOMG.0000037159. 63644.81 15300010 (Pubitemid 39177500)
23. M Kunnimalaiyaan H Chen 2007 Tumor suppressor role of Notch-1 signaling in neuroendocrine tumors Oncologist 12 535 542 10.1634/theoncologist.12-5-535 1:CAS:528:DC%2BD2sXntVyns7g%3D 17522241 (Pubitemid 350012116)
24. IC Cuevas AL Slocum P Jun, et al. 2005 Meningioma transcript profiles reveal deregulated Notch signaling pathway Cancer Res 65 5070 5075 10.1158/0008-5472.CAN-05-0240 1:CAS:528:DC%2BD2MXltFemtb0%3D 15958550 (Pubitemid 40827315)
25. BW Purow RM Haque MW Noel, et al. 2005 Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation Cancer Res 65 2353 2363 10.1158/0008-5472.CAN-04-1890 1:CAS:528:DC%2BD2MXisFGns78%3D 15781650 (Pubitemid 40490146)
26. M Kanamori T Kawaguchi JM Nigro, et al. 2007 Contribution of Notch signaling activation to human glioblastoma multiforme J Neurosurg 106 417 427 10.3171/jns.2007.106.3.417 17367064
27. AH Shih EC Holland 2006 Notch signaling enhances nestin expression in gliomas Neoplasia 8 1072 1082 10.1593/neo.06526 1:CAS:528:DC%2BD2sXjsVGitA%3D%3D 17217625 (Pubitemid 44936157)
28. L Dang X Fan A Chaudhry, et al. 2006 Notch3 signaling initiates choroid plexus tumor formation Oncogene 25 487 491 1:CAS:528:DC%2BD28Xlt1egtQ%3D%3D 16186803
29. F Radtke K Raj 2003 The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat Rev Cancer 3 756 767 10.1038/nrc1186 1:CAS:528: DC%2BD3sXotFChs7s%3D 14570040
30. JJ Breunig J Silbereis FM Vaccarino, et al. 2007 Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus Proc Natl Acad Sci U S A 104 20558 20563 10.1073/pnas.0710156104 1:CAS:528:DC%2BD1cXjt12msQ%3D%3D 18077357
31. A Tokunaga J Kohyama T Yoshida, et al. 2004 Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain J Neurochem 90 142 154 10.1111/j.1471-4159.2004.02470.x 1:CAS:528:DC%2BD2cXlvFKls7c%3D 15198674 (Pubitemid 38879169)
32. MK Taylor K Yeager SJ Morrison 2007 Physiological Notch signaling promotes gliogenesis in the developing peripheral and central nervous systems Development 134 2435 2447 10.1242/dev.005520 1:CAS:528:DC%2BD2sXosVKrtLw%3D 17537790 (Pubitemid 47074138)
33. DJ Solecki XL Liu T Tomoda, et al. 2001 Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation Neuron 31 557 568 10.1016/S0896-6273(01)00395-6 1:CAS:528:DC%2BD3MXmvV2itbo%3D 11545715 (Pubitemid 32835111)
34. DK Irvin SD Zurcher T Nguyen, et al. 2001 Expression patterns of Notch1, Notch2, and Notch3 suggest multiple functional roles for the Notch-DSL signaling system during brain development J Comp Neurol 436 167 181 10.1002/cne.1059 1:CAS:528:DC%2BD3MXls1Smu7Y%3D 11438922 (Pubitemid 32622529)
35. D Bellavia S Checquolo AF Campese, et al. 2008 Notch3: from subtle structural differences to functional diversity Oncogene 27 5092 5098 10.1038/onc.2008.230 1:CAS:528:DC%2BD1cXhtVGgtLfJ 18758477
36. M Katoh 2007 Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis Stem Cell Rev 3 30 38 10.1007/s12015-007-0006-6 1:CAS:528:DC%2BD2sXhtVent7nI 17873379 (Pubitemid 47472809)
37. AS McElhinny JL Li L Wu 2008 Mastermind-like transcriptional co-activators: emerging roles in regulating cross talk among multiple signaling pathways Oncogene 27 5138 5147 10.1038/onc.2008.228 1:CAS:528:DC%2BD1cXhtVGgtLfL 18758483