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Volumn 15, Issue 4, 2009, Pages 567-577

Aminobisphosphonate stimulates bone regeneration and enforces consolidation of titanium implant into a new rat caudal vertebrae model

Author keywords

Aminobisphosphonates (Zometa ); Biomechanical measurement; Bone regeneration; Micro computer tomography (micro CT); New implant osseointegration model; Osteo neogenesis

Indexed keywords

ZOLEDRONIC ACID;

EID: 75049084669     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12253-009-9156-y     Document Type: Article
Times cited : (18)

References (46)
  • 1
    • 0034285013 scopus 로고    scopus 로고
    • The osteoblast: A sophisticated fibroblast under central surveillance
    • DOI 10.1126/science.289.5484.1501
    • P Ducy T Schinke G Karsenty 2000 The osteoblast: a sophisticated fibroblast under central surveillance Science 289 1501 1504 10.1126/science.289. 5484.1501 1:CAS:528:DC%2BD3cXmt1KgsLg%3D 10968779 (Pubitemid 30677463)
    • (2000) Science , vol.289 , Issue.5484 , pp. 1501-1504
    • Ducy, P.1    Schinke, T.2    Karsenty, G.3
  • 2
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • DOI 10.1126/science.289.5484.1504
    • SL Teitelbaum 2000 Bone resorption by osteoclasts Science 289 1504 1508 10.1126/science.289.5484.1504 1:CAS:528:DC%2BD3cXmt1KgsLk%3D 10968780 (Pubitemid 30677464)
    • (2000) Science , vol.289 , Issue.5484 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 3
    • 0037078328 scopus 로고    scopus 로고
    • Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes
    • DOI 10.1083/jcb.200204060
    • J Skillington L Choy R Derynck 2002 Bone morphogenetic protein and retinoic acid signalling cooperate to induce osteoblast differentiation of preadipocytes J Cell Biol 159 135 146 10.1083/jcb.200204060 1:CAS:528: DC%2BD38XnvFGkt7g%3D 12379805 (Pubitemid 35191525)
    • (2002) Journal of Cell Biology , vol.159 , Issue.1 , pp. 135-146
    • Skillington, J.1    Choy, L.2    Derynck, R.3
  • 5
    • 0034874481 scopus 로고    scopus 로고
    • Cancellous bone remodelling occurs in specialized compartments lined by cells expressing osteoblastic markers
    • 10.1359/jbmr.2001.16.9.1575 1:STN:280:DC%2BD3Mvpslenuw%3D%3D 11547826
    • EM Hauge D Ovesel EF Eriksen L Mosekilde F Melsen 2001 Cancellous bone remodelling occurs in specialized compartments lined by cells expressing osteoblastic markers J Bone Miner Res 16 1575 1582 10.1359/jbmr.2001.16.9.1575 1:STN:280:DC%2BD3Mvpslenuw%3D%3D 11547826
    • (2001) J Bone Miner Res , vol.16 , pp. 1575-1582
    • Hauge, E.M.1    Ovesel, D.2    Eriksen, E.F.3    Mosekilde, L.4    Melsen, F.5
  • 7
    • 34250172718 scopus 로고    scopus 로고
    • Reconciling the roles of FAK in osteoblast differentiation, osteoclast remodeling, and bone regeneration
    • DOI 10.1016/j.bone.2007.01.024, PII S8756328207000452
    • JB Kim P Leucht CA Luppen YJ Park HE Beggs CH Damsky JA Helms 2007 Reconciling the roles of FAK in osteoblast differentiation, osteoclast remodeling, and bone regeneration Bone 41 39 51 10.1016/j.bone.2007.01.024 1:CAS:528:DC%2BD2sXmsFKku7o%3D 17459803 (Pubitemid 46901054)
    • (2007) Bone , vol.41 , Issue.1 , pp. 39-51
    • Kim, J.-B.1    Leucht, P.2    Luppen, C.A.3    Park, Y.J.4    Beggs, H.E.5    Damsky, C.H.6    Helms, J.A.7
  • 8
    • 34447132814 scopus 로고    scopus 로고
    • Skeletal remodeling in health and disease
    • DOI 10.1038/nm1593, PII NM1593
    • M Zaidi 2007 Skeletal remodeling in health and disease Nature Med 13 791 798 10.1038/nm1593 1:CAS:528:DC%2BD2sXnsFWmtro%3D 17618270 (Pubitemid 47038187)
    • (2007) Nature Medicine , vol.13 , Issue.7 , pp. 791-801
    • Zaidi, M.1
  • 9
    • 10144241022 scopus 로고    scopus 로고
    • Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis
    • 10.1172/JCI118947 1:CAS:528:DyaK28XmtVCmu70%3D 8833902
    • TA Guise JJ Yin SD Taylor Y Kumagai M Dallas BF Boyce T Yoneda GR Mundy 1996 Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis J Clin Invest 98 1544 1549 10.1172/JCI118947 1:CAS:528:DyaK28XmtVCmu70%3D 8833902
    • (1996) J Clin Invest , vol.98 , pp. 1544-1549
    • Guise, T.A.1    Yin, J.J.2    Taylor, S.D.3    Kumagai, Y.4    Dallas, M.5    Boyce, B.F.6    Yoneda, T.7    Mundy, G.R.8
  • 10
    • 0034284550 scopus 로고    scopus 로고
    • Therapeutic approaches to bone diseases
    • DOI 10.1126/science.289.5484.1508
    • GA Rodan TJ Martin 2000 Therapeutic approaches to bone diseases Science 289 1508 1514 10.1126/science.289.5484.1508 1:CAS:528:DC%2BD3cXmt1Kgsb4%3D 10968781 (Pubitemid 30677465)
    • (2000) Science , vol.289 , Issue.5484 , pp. 1508-1514
    • Rodan, G.A.1    Martin, T.J.2
  • 11
    • 33644666787 scopus 로고    scopus 로고
    • Bisphosphonates for treatment and prevention of bone metastases
    • DOI 10.1200/JCO.2005.02.9579
    • MD Michaelson MR Smith 2005 Bisphosphonates for treatment and prevention of bone metastases J Clin Oncol 23 8219 8223 10.1200/JCO.2005.02.9579 1:CAS:528:DC%2BD2MXht1yntbnO 16278476 (Pubitemid 46211558)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.32 , pp. 8219-8224
    • Michaelson, M.D.1    Smith, M.R.2
  • 12
    • 0034214362 scopus 로고    scopus 로고
    • Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases
    • 1:CAS:528:DC%2BD3cXjvFOltrY%3D 10850442
    • S Boissier M Ferreras O Peyruchaud 2000 Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases Cancer Res 60 2949 2954 1:CAS:528:DC%2BD3cXjvFOltrY%3D 10850442
    • (2000) Cancer Res , vol.60 , pp. 2949-2954
    • Boissier, S.1    Ferreras, M.2    Peyruchaud, O.3
  • 13
    • 37549048980 scopus 로고    scopus 로고
    • Healing cranial defects with AdRunx2-transduced marrow stromal cells
    • 10.1177/154405910708601213 1:CAS:528:DC%2BD2sXhsVygtr7P 18037657
    • Z Zhao Z Wang C Ge P Krebsbach RT Franceschi 2007 Healing cranial defects with AdRunx2-transduced marrow stromal cells J Dent Res 86 1207 1211 10.1177/154405910708601213 1:CAS:528:DC%2BD2sXhsVygtr7P 18037657
    • (2007) J Dent Res , vol.86 , pp. 1207-1211
    • Zhao, Z.1    Wang, Z.2    Ge, C.3    Krebsbach, P.4    Franceschi, R.T.5
  • 14
    • 22744443730 scopus 로고    scopus 로고
    • A new population of human adult dental pulp stem cells: A useful source of living autologous fibrous bone tissue (LAB)
    • 10.1359/JBMR.050325 16007337
    • G Laino R d'Aquino A Graziano V Lanza F Carinci F Naro G Pirozzi G Papaccio 2005 A new population of human adult dental pulp stem cells: a useful source of living autologous fibrous bone tissue (LAB) J Bone Miner Res 20 1394 1402 10.1359/JBMR.050325 16007337
    • (2005) J Bone Miner Res , vol.20 , pp. 1394-1402
    • Laino, G.1    D'Aquino, R.2    Graziano, A.3    Lanza, V.4    Carinci, F.5    Naro, F.6    Pirozzi, G.7    Papaccio, G.8
  • 15
    • 3843138970 scopus 로고    scopus 로고
    • Stem-cell-based tissue engineering of murine teeth
    • 10.1177/154405910408300702 1:STN:280:DC%2BD2czhs1Clsg%3D%3D 15218039
    • A Ohazama SA Modino I Miletich PT Sharpe 2004 Stem-cell-based tissue engineering of murine teeth J Dent Res 83 518 522 10.1177/154405910408300702 1:STN:280:DC%2BD2czhs1Clsg%3D%3D 15218039
    • (2004) J Dent Res , vol.83 , pp. 518-522
    • Ohazama, A.1    Modino, S.A.2    Miletich, I.3    Sharpe, P.T.4
  • 17
    • 34248549208 scopus 로고    scopus 로고
    • Osseointegrated wrist-joint prosthesis: A 15-year follow-up with focus on bony fixation
    • 10.1080/02844310701318346 17486519
    • G Lundborg J Besjakov PI Bränemark 2007 Osseointegrated wrist-joint prosthesis: a 15-year follow-up with focus on bony fixation Scand J Plast Reconstr Surg Hand Surg 41 130 137 10.1080/02844310701318346 17486519
    • (2007) Scand J Plast Reconstr Surg Hand Surg , vol.41 , pp. 130-137
    • Lundborg, G.1    Besjakov, J.2    Bränemark, P.I.3
  • 18
    • 34249936024 scopus 로고    scopus 로고
    • Forces and bond dynamics in cell adhesion
    • DOI 10.1126/science.1137592
    • EA Evans DA Calderwood 2007 Forces and bond dynamics in cell adhesion Science 316 1148 1153 10.1126/science.1137592 1:CAS:528:DC%2BD2sXls1Kit7Y%3D 17525329 (Pubitemid 46877469)
    • (2007) Science , vol.316 , Issue.5828 , pp. 1148-1153
    • Evans, E.A.1    Calderwood, D.A.2
  • 20
    • 0031977199 scopus 로고    scopus 로고
    • Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras
    • DOI 10.1359/jbmr.1998.13.4.581
    • SP Luckman DE Hughes FP Coxon RGG Russell MJ Rogers 1998 Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras J Bone Mineral Res 13 581 589 10.1359/jbmr.1998.13.4.581 1:CAS:528:DyaK1cXisFyktb8%3D (Pubitemid 28163009)
    • (1998) Journal of Bone and Mineral Research , vol.13 , Issue.4 , pp. 581-589
    • Luckman, S.P.1    Hughes, D.E.2    Coxon, F.P.3    Russell, R.G.G.4    Rogers, M.J.5
  • 22
    • 0345161422 scopus 로고    scopus 로고
    • The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates
    • DOI 10.1359/jbmr.1999.14.5.722
    • E Van Beek C Lowik G Van Der Pluijm S Papapoulos 1999 The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: a clue to the mechanism of action of nitrogen-containing bisphosphonates J Bone Mineral Res 14 722 729 10.1359/jbmr.1999.14.5.722 (Pubitemid 29210598)
    • (1999) Journal of Bone and Mineral Research , vol.14 , Issue.5 , pp. 722-729
    • Van Beek, E.1    Lowik, C.2    Van Der Pluijm, G.3    Papapoulos, S.4
  • 23
    • 0036791075 scopus 로고    scopus 로고
    • Use of zoledronate to treat osteoblastic versus osteolytic lesions in a severe-combined-immunodeficient mouse model
    • 1:CAS:528:DC%2BD38Xnsl2lsb0%3D 12359769
    • YP Lee EM Schwarz M Davies 2002 Use of zoledronate to treat osteoblastic versus osteolytic lesions in a severe-combined-immunodeficient mouse model Cancer Res 62 5564 5570 1:CAS:528:DC%2BD38Xnsl2lsb0%3D 12359769
    • (2002) Cancer Res , vol.62 , pp. 5564-5570
    • Lee, Y.P.1    Schwarz, E.M.2    Davies, M.3
  • 24
    • 27244454807 scopus 로고    scopus 로고
    • Jaw bone necrosis without previous dental extractions associated with the use of bisphosphonates (pamidronate and zoledronate): A four-case report
    • DOI 10.1111/j.1600-0714.2005.00351.x
    • E Merigo M Manfredi M Meleti D Corradi P Vescovi 2005 Jaw bone necrosis without previous dental extractions associated with the use of bisphosphonates (pamidronate and zoledronate) J Oral Pathol 34 613 614 10.1111/j.1600-0714.2005. 00351.x 1:STN:280:DC%2BD2MrivF2huw%3D%3D (Pubitemid 41512948)
    • (2005) Journal of Oral Pathology and Medicine , vol.34 , Issue.10 , pp. 613-617
    • Merigo, E.1    Manfredi, M.2    Meleti, M.3    Corradi, D.4    Vescovi, P.5
  • 25
    • 33645242370 scopus 로고    scopus 로고
    • Osteonecrosis of the mandible or maxilla associated with the use of new generation bisphosphonates
    • DOI 10.1097/01.mlg.0000187398.51857.3c, PII 0000553720060100000023
    • MC Farrugia DJ Summerlin E Krowiak T Huntley S Freeman R Borrowdale C Tomich 2006 Osteonecrosis of the mandible or maxilla associated with the use of new generation bisphosphonates Laryngoscope 116 115 120 10.1097/01.mlg. 0000187398.51857.3c 16481822 (Pubitemid 44383974)
    • (2006) Laryngoscope , vol.116 , Issue.1 , pp. 115-120
    • Farrugia, M.C.1    Summerlin, D.-J.2    Krowiak, E.3    Huntley, T.4    Freeman, S.5    Borrowdale, R.6    Tomich, C.7
  • 27
    • 0034326253 scopus 로고    scopus 로고
    • Bisphosphonates directly regulate cell proliferation, differentiation, and gene expression in human osteoblasts
    • 1:CAS:528:DC%2BD3cXotV2ls7g%3D 11085520
    • GG Reinholz B Getz L Pederson ES Sanders M Subramaniam JN Ingle TC Spelsberg 2000 Bisphosphonates directly regulate cell proliferation, differentiation, and gene expression in human osteoblasts Cancer Res 60 6001 6007 1:CAS:528:DC%2BD3cXotV2ls7g%3D 11085520
    • (2000) Cancer Res , vol.60 , pp. 6001-6007
    • Reinholz, G.G.1    Getz, B.2    Pederson, L.3    Sanders, E.S.4    Subramaniam, M.5    Ingle, J.N.6    Spelsberg, T.C.7
  • 28
    • 0035987949 scopus 로고    scopus 로고
    • Bisphosphonates influence the proliferation and maturation of normal human osteoblasts
    • 12109626
    • O Fromigué JJ Body 2002 Bisphosphonates influence the proliferation and maturation of normal human osteoblasts J Endocrinol Invest 25 539 546 12109626
    • (2002) J Endocrinol Invest , vol.25 , pp. 539-546
    • Fromigué, O.1    Body, J.J.2
  • 29
    • 23244462780 scopus 로고    scopus 로고
    • Effects of bisphosphonates on proliferation and osteoblast differentiation of human bone marrow stromal cells
    • DOI 10.1016/j.biomaterials.2005.04.059, PII S014296120500373X
    • F von Knoch C Jaquiery M Kowalsky S Schaeren C Alabre I Martin HE Rubash AS Shanbhag 2005 Effects of bisphosphonates on proliferation and osteoblast differentiation of human bone marrow stromal cells Biomaterials 34 6941 6949 10.1016/j.biomaterials.2005.04.059 (Pubitemid 41095518)
    • (2005) Biomaterials , vol.26 , Issue.34 , pp. 6941-6949
    • Von Knoch, F.1    Jaquiery, C.2    Kowalsky, M.3    Schaeren, S.4    Alabre, C.5    Martin, I.6    Rubash, H.E.7    Shanbhag, A.S.8
  • 30
    • 14044263654 scopus 로고    scopus 로고
    • Short-term zoledronic acid treatment increases bone mineral density and marrow clonogenic fibroblast progenitors after allogeneic stem cell transplantation
    • DOI 10.1210/jc.2004-0509
    • L Tauchmanovà P Ricci B Serio G Lombardi A Colao B Rotoli C Selleri 2005 Short-term Zoledronic acid treatment increases bone mineral density and marrow clonogenic fibroblast progenitors after allogeneic stem cell transplantation J Clin Endocrinol Metab 90 627 634 10.1210/jc.2004-0509 15546907 (Pubitemid 40279172)
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , Issue.2 , pp. 627-634
    • Tauchmanova, L.1    Ricci, P.2    Serio, B.3    Lombardi, G.4    Colao, A.5    Rotoli, B.6    Selleri, C.7
  • 31
    • 0035705959 scopus 로고    scopus 로고
    • Intramedullary osseointegration: Development of a rodent model and study of histology and neuropeptide changes around titanium implants
    • 1:STN:280:DC%2BD3MzhvVGgtg%3D%3D
    • M Ysander R Branemark K Olmarker RR Myers 2001 Intramedullary osseointegration: development of a rodent model and study of histology and neuropeptide changes around titanium implants J Rehabilit Res Dev 38 183 190 1:STN:280:DC%2BD3MzhvVGgtg%3D%3D
    • (2001) J Rehabilit Res Dev , vol.38 , pp. 183-190
    • Ysander, M.1    Branemark, R.2    Olmarker, K.3    Myers, R.R.4
  • 36
    • 0026320852 scopus 로고
    • Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure
    • 10.1172/JCI115539 1:CAS:528:DyaK38XjsVGgtA%3D%3D 1661297
    • M Sato W Grasser N Endo R Akins H Simmons D D Thompson E Golub GA Rodan 1991 Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure J Clin Invest 88 2095 2105 10.1172/JCI115539 1:CAS:528:DyaK38XjsVGgtA%3D%3D 1661297
    • (1991) J Clin Invest , vol.88 , pp. 2095-2105
    • Sato, M.1    Grasser, W.2    Endo, N.3    Akins, R.4    Simmons, H.5    Thompson, D.D.6    Golub, E.7    Rodan, G.A.8
  • 37
    • 0033930168 scopus 로고    scopus 로고
    • Protein geranylgeranylation is required for osteoclast formation, function, and survival: Inhibition by bisphosphonates and GGTI-298
    • 10.1359/jbmr.2000.15.8.1467 1:CAS:528:DC%2BD3cXlvVSjsLw%3D 10934645
    • FP Coxon MH Helfrich R Van't Hof 2000 Protein geranylgeranylation is required for osteoclast formation, function, and survival: Inhibition by bisphosphonates and GGTI-298 J Bone Miner Res 15 1467 1476 10.1359/jbmr.2000.15. 8.1467 1:CAS:528:DC%2BD3cXlvVSjsLw%3D 10934645
    • (2000) J Bone Miner Res , vol.15 , pp. 1467-1476
    • Coxon, F.P.1    Helfrich, M.H.2    Van'T Hof, R.3
  • 38
    • 4444265541 scopus 로고    scopus 로고
    • Hypertrophic pulmonary osteoarthropathy: Control of pain and symptoms with pamidronate
    • 10.1007/s10067-004-0941-4 15293094
    • H Amital YH Applbaum L Vasiliev A Rubinow 2004 Hypertrophic pulmonary osteoarthropathy: control of pain and symptoms with pamidronate Clin Rheumatol 23 330 332 10.1007/s10067-004-0941-4 15293094
    • (2004) Clin Rheumatol , vol.23 , pp. 330-332
    • Amital, H.1    Applbaum, Y.H.2    Vasiliev, L.3    Rubinow, A.4
  • 39
    • 2942750232 scopus 로고    scopus 로고
    • Treatment of fibrous dysplasia of bone with intravenous pamidronate: Long-term effectiveness and evaluation of predictors of response to treatment
    • DOI 10.1016/j.bone.2004.03.004, PII S8756328204001103
    • RD Chapurlat P Hugueny PD Delmas PJ Meunier 2004 Treatment of fibrous dysplasia of bone with intravenous pamidronate: long-term effectiveness and evaluation of predictors of response to treatment Bone 35 235 242 10.1016/j.bone.2004.03.004 1:CAS:528:DC%2BD2cXltVGjs7k%3D 15207763 (Pubitemid 38789170)
    • (2004) Bone , vol.35 , Issue.1 , pp. 235-242
    • Chapurlat, R.D.1    Hugueny, P.2    Delmas, P.D.3    Meunier, P.J.4
  • 40
    • 34548235937 scopus 로고    scopus 로고
    • Optimal timing of a single dose of zoledronic acid to increase strength in rat fracture repair
    • DOI 10.1359/jbmr.070318
    • N Amant M McDonald C Godfrey L Bilston D Little 2007 Optimal timing of a single dose of zoledronic acid to increase strength in rat fracture repair J Bone Miner Res 22 867 876 10.1359/jbmr.070318 (Pubitemid 351339747)
    • (2007) Journal of Bone and Mineral Research , vol.22 , Issue.6 , pp. 867-876
    • Amanat, N.1    McDonald, M.2    Godfrey, C.3    Bilston, L.4    Little, D.5
  • 41
    • 34548486474 scopus 로고    scopus 로고
    • Sequential treatment with intermittent low-dose human parathyroid hormone (1-34) and bisphosphonate enhances large-size skeletal reconstruction by vascularized bone transplantation
    • DOI 10.1007/s00223-007-9056-7
    • T Hashimoto M Shigetomi T Ohno T Matsunaga K Muramatsu H Tanaka T Sugiyama T Taguchi 2007 Sequential treatment with intermittent low-dose human parathyroid hormone (1-34) and bisphosphonate enhances large-size skeletal reconstruction by vascularized bone transplantation Calcif Tissue Int 81 3 232 239 10.1007/s00223-007-9056-7 1:CAS:528:DC%2BD2sXpvF2rtb8%3D 17674071 (Pubitemid 47373358)
    • (2007) Calcified Tissue International , vol.81 , Issue.3 , pp. 232-239
    • Hashimoto, T.1    Shigetomi, M.2    Ohno, T.3    Matsunaga, T.4    Muramatsu, K.5    Tanaka, H.6    Sugiyama, T.7    Taguchi, T.8
  • 42
    • 0034980406 scopus 로고    scopus 로고
    • Preclinical studies with zoledronic acid and other bisphosphonates: Impact on the bone microenvironment
    • 10.1016/S0093-7754(01)90263-5 1:STN:280:DC%2BD3M3ltVyrsw%3D%3D 11346863
    • GR Mundy T Yoneda T Hiraga 2001 Preclinical studies with zoledronic acid and other bisphosphonates: Impact on the bone microenvironment Semin Oncol 28 6 35 44 10.1016/S0093-7754(01)90263-5 1:STN:280:DC%2BD3M3ltVyrsw%3D%3D 11346863
    • (2001) Semin Oncol , vol.28 , Issue.6 , pp. 35-44
    • Mundy, G.R.1    Yoneda, T.2    Hiraga, T.3
  • 43
    • 0034548835 scopus 로고    scopus 로고
    • Ontogenic emergence of the hematon, a morphogenic stromal unit that supports multipotential hemopoietic progenitors in mouse bone marrow
    • 1:CAS:528:DC%2BD3cXosVGntLg%3D 11090058
    • I Blazsek J Chagraoui B Péault 2000 Ontogenic emergence of the hematon, a morphogenic stromal unit that supports multipotential hemopoietic progenitors in mouse bone marrow Blood 96 3763 3771 1:CAS:528: DC%2BD3cXosVGntLg%3D 11090058
    • (2000) Blood , vol.96 , pp. 3763-3771
    • Blazsek, I.1    Chagraoui, J.2    Péault, B.3


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