Progressive gray matter changes in first episode schizophrenia: A 4-year longitudinal magnetic resonance study using VBM

Schizophrenia Research

Volumn 114, Issue 1-3, 2009, Pages 136-143

  Mané, Anna ^a,e   Falcon, Carles ^b,c   Mateos, J Javier ^f   Fernandez Egea, Emilio ^a,g,h   Horga, Guillermo ^a   Lomeña, Francisco ^a,b,d,i   Bargalló, Nuria ^b,i   Prats Galino, Alberto ^j   Bernardo, Miguel ^a,b,d   Parellada, Eduard ^a,b,d  

^a Institute of Neuroscience   (Spain)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^c BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^d CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE SALUD MENTAL CIBERSAM   (Spain)

^e HOSPITAL DEL MAR   (Spain)

^f CETIR   (Spain)

^g UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^h CAMBRIDGESHIRE AND PETERBOROUGH NHS FOUNDATION TRUST   (United Kingdom)

ⁱ HOSPITAL CLÍNIC   (Spain)

^j UNIVERSITY OF BARCELONA   (Spain)

more..

Author keywords

Cuneus; GAF; Outcome

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; NEUROLEPTIC AGENT; ZUCLOPENTHIXOL;

ADULT; ARTICLE; BRAIN DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE COURSE; FEMALE; FRONTAL LOBE; FUNCTIONAL ASSESSMENT; GRAY MATTER; HUMAN; LONGITUDINAL STUDY; MALE; MORPHOMETRICS; NUCLEAR MAGNETIC RESONANCE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SCHIZOIDISM; SCHIZOPHRENIA; SCHIZOPHRENIFORM DISORDER; TEMPORAL LOBE;

BRAIN MAPPING; CEREBRAL CORTEX; DISEASE PROGRESSION; FAMILY HEALTH; FEMALE; FUNCTIONAL LATERALITY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; NEUROPSYCHOLOGICAL TESTS; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTIC DISORDERS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 69849088544     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2009.07.014     Document Type: Article

References (59)

1. Aasly J., Storsaeter O., Nilsen G., Smevik O., and Rinck P. Minor structural brain changes in young drug abusers. A magnetic resonance study. Acta Neurol. Scand. 87 (1993) 210-214
2. Andreasen N.C., Nopoulos P., O'Leary D.S., Miller D.D., Wassink T., and Flaum M. Defining the phenotype of schizophrenia: cognitive dysmetria and its neural mechanisms. Biol. Psychiatry 46 (1999) 908-920
3. Ashburner J., and Friston K.J. Voxel-based morphometry-the methods. Neuroimage. 11 (2000) 805-821
4. Ashburner J., and Friston K.J. Unified segmentation. Neuroimage. 26 (2005) 839-851
5. Bersani G., Orlandi V., Kotzalidis G.D., and Pancheri P. Cannabis and schizophrenia: impact on onset, course, psychopathology and outcomes. Eur. Arch. Psychiatry Clin. Neurosci. 252 (2002) 86-92
6. Borgwardt S.J., McGuire P.K., Aston J., Berger G., Dazzan P., Gschwandtner U., Pflüger M., D'Souza M., Radue E., and Riecher-Rössler A. Structural brain abnormalities in individuals with an at-risk mental state who later develop psychosis. Br. J. Psychiatry 191 Suppl. 51 (2007) 69-75
7. Borgwardt S.J., McGuire P., Aston J., Gschwandtner U., Pflüger M.O., Stieglitz R., Radue E., and Riecher-Rössler A. Reductions in frontal, temporal and parietal volume associated with the onset of psychosis. Schizophr. Res. 16 (2008) 108-114
8. Borgwardt S.J., Dickey C., Hulshoff Pol H., Whitford T.J., and DeLisi L.E. Workshop on defining the significance of progressive brain change in schizophrenia: December 12, 2008 American College of Neuropsychopharmacology (ACNP) all-day satellite, Scottsdale, Arizona. The rapporteurs' report. Schizophr. Res. 112 (2009) 32-45
9. Cahn W., Hulshoff Pol H.E., Lems E.B., van Haren N.E., Schnack H.G., van der Linden J.A., Schothorst P.F., van E.H., and Kahn R.S. Brain volume changes in first-episode schizophrenia: a 1-year follow-up study. Arch. Gen. Psychiatry 59 (2002) 1002-1010
10. Cahn W., Hulshoff Pol H.E., Caspers E., van Haren N.E., Schnack H.G., and Kahn R.S. Cannabis and brain morphology in recent-onset schizophrenia. Schizophr. Res. 67 (2004) 305-307
11. Cahn W., van Haren N.E., Hulshoff Pol H.E., Schnack H.G., Caspers E., Laponder D.A., and Kahn R.S. Brain volume changes in the first year of illness and 5-year outcome of schizophrenia. Br. J. Psychiatry 189 (2006) 381-382
12. Caviness Jr. V.S., Lange N.T., Makris N., Herbert M.R., and Kennedy D.N. MRI-based brain volumetrics: emergence of a developmental brain science. Brain Develop. 21 (1999) 289-295
13. Crespo-Facorro B., Paradiso S., Andreasen N.C., O'Leary D.S., Watkins G.L., Boles Ponto L.L., and Hichwa R.D. Recalling word lists reveals "cognitive dysmetria" in schizophrenia: a positron emission tomography study. Am. J. Psychiatry 156 (1999) 386-392
14. Crespo-Facorro B., Kim J., Andreasen N.C., O'Leary D.S., Bockholt H.J., and Magnotta V. Insular cortex abnormalities in schizophrenia: a structural magnetic resonance imaging study of first-episode patients. Schizophr. Res. 46 (2000) 35-43
15. Crow T.J., MacMillan J.F., Johnson A.L., and Johnstone E.C. A randomised controlled trial of prophylactic neuroleptic treatment. Br. J. Psychiatry 148 (1986) 120-127
16. DeLisi L.E., Stritzke P.H., Holan V., Anand A., Boccio A., Kuschner M., Riordan H., McClelland J., and VanEyle O. Brain morphological changes in 1st episode cases of schizophrenia: are they progressive?. Schizophr. Res. 5 (1991) 206-208
17. DeLisi L.E., Sakuma M., Tew W., Kushner M., Hoff A.L., and Grimson R. Schizophrenia as a chronic active brain process: a study of progressive brain structural change subsequent to the onset of schizophrenia. Psychiatry Res. 74 (1997) 129-140
18. DeLisi L.E., DeLisi L.E., Sakuma M., Ge S., and Kushner M. Association of brain structural change with the heterogeneous course of schizophrenia from early childhood through five years subsequent to a first hospitalization. Psychiatry Res. 84 2-3 (1998) 75-88
19. DeLisi L.E., Sakuma M., Maurizio A.M., Relja M., and Hoff A.L. Cerebral ventricular change over the first 10 years after the onset of schizophrenia. Psychiatry Res. 130 (2004) 57-70
20. Giuliani N.R., Calhoun V.D., Pearlson G.D., Francis A., and Buchanan R.W. Voxel-based morphometry versus region of interest: a comparison of two methods for analyzing gray matter differences in schizophrenia. Schizophr. Res. 74 (2005) 135-147
21. Glantz L.A., Gilmore J.H., Lieberman J.A., and Jarskog L.F. Apoptotic mechanisms and the synaptic pathology of schizophrenia. Schizophr. Res. 81 (2006) 47-63
22. Grech A., Van O.J., Jones P.B., Lewis S.W., and Murray R.M. Cannabis use and outcome of recent onset psychosis. Eur. Psychiatr. 20 (2005) 349-353
23. Green M.F., Kern R.S., and Heaton R.K. Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS. Schizophr. Res. 72 (2004) 41-51
24. Gur R.E., Cowell P., Turetsky B.I., Gallacher F., Cannon T., Bilker W., and Gur R.C. A follow-up magnetic resonance imaging study of schizophrenia. Relationship of neuroanatomical changes to clinical and neurobehavioral measures. Arch. Gen. Psychiatry 55 (1998) 145-152
25. Ho B.C., Andreasen N.C., Nopoulos P., Arndt S., Magnotta V., and Flaum M. Progressive structural brain abnormalities and their relationship to clinical outcome: a longitudinal magnetic resonance imaging study early in schizophrenia. Arch. Gen. Psychiatry 60 (2003) 585-594
26. Honea R., Crow T.J., Passingham D., and Mackay C.E. Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies. Am. J. Psychiatry 162 (2005) 2233-2245
27. Job D.E., Whalley H.C., McConnell S., Glabus M., Johnstone E.C., and Lawrie S.M. Voxel-based morphometry of grey matter densities in subjects at high risk of schizophrenia. Schizophr. Res. 64 (2003) 1-13
28. Job D.E., Whalley H.C., Johnstone E.C., and Lawrie S.M. Grey matter changes over time in high risk subjects developing schizophrenia. Neuroimage 25 (2005) 1023-1030
29. Kasai K., Shenton M.E., Salisbury D.F., Hirayasu Y., Lee C.U., Ciszewski A.A., Yurgelun-Todd D., Kikinis R., Jolesz F.A., and McCarley R.W. Progressive decrease of left superior temporal gyrus gray matter volume in patients with first-episode schizophrenia. Am. J. Psychiatry 160 (2003) 156-164
30. Kasai K., Shenton M.E., Salisbury D.F., Hirayasu Y., Onitsuka T., Spencer M.H., Yurgelun-Todd D.A., Kikinis R., Jolesz F.A., and McCarley R.W. Progressive decrease of left Heschl gyrus and planum temporale gray matter volume in first-episode schizophrenia: a longitudinal magnetic resonance imaging study. Arch. Gen. Psychiatry 60 (2003) 766-775
31. Kay S.R., Fiszbein A., Vital-Herne M., and Fuentes L.S. The positive and negative syndrome scale-Spanish adaptation. J. of Nerv. Ment. Dis. 178 (1990) 510-517
32. Keshavan M.S., Haas G.L., Kahn C.E., Aguilar E., Dick E.L., Schooler N.R., Sweeney J.A., and Pettegrew J.W. Superior temporal gyrus and the course of early schizophrenia: progressive, static, or reversible?. J. Psychiatr. Res. 32 (1998) 161-167
33. Kircher T.T., Liddle P.F., Brammer M.J., Williams S.C., Murray R.M., and McGuire P.K. Neural correlates of formal thought disorder in schizophrenia: preliminary findings from a functional magnetic resonance imaging study. Arch. Gen. Psychiatry 58 (2001) 769-774
34. Levitan C., Ward P.B., and Catts S.V. Superior temporal gyral volumes and laterality correlates of auditory hallucinations in schizophrenia. Biol. Psychiatry 46 (1999) 955-962
35. Lewis D.A., and Lieberman J.A. Catching up on schizophrenia: natural history and neurobiology. Neuron 28 (2000) 325-334
36. Lieberman J.A., Sheitman B.B., and Kinon B.J. Neurochemical sensitization in the pathophysiology of schizophrenia: deficits and dysfunction in neuronal regulation and plasticity. Neuropsychopharmacology 17 (1997) 205-229
37. Lieberman J., Chakos M., Wu H., Alvir J., Hoffman E., Robinson D., and Bilder R. Longitudinal study of brain morphology in first episode schizophrenia. Biol. Psychiatry 49 (2001) 487-499
38. Lieberman J.A., Tollefson G.D., Charles C., Zipursky R., Sharma T., Kahn R.S., Keefe R.S., Green A.I., Gur R.E., McEvoy J., Perkins D., Hamer R.M., Gu H., and Tohen M. Antipsychotic drug effects on brain morphology in first-episode psychosis. Arch. Gen. Psychiatry 62 (2005) 361-370
39. Loebel A.D., Lieberman J.A., Alvir J.M., Mayerhoff D.I., Geisler S.H., and Szymanski S.R. Duration of psychosis and outcome in first-episode schizophrenia. Am. J. Psychiatry 149 (1992) 1183-1188
40. Meisenzahl E.M., Koutsouleris N., Bottlender R., Scheuerecker J., Jäger M., Teipel S.J., Holzinger S., Frodl T., Preuss U., Schmitt G., Burgermeister B., Reiser M., Born C., and Möller H.-J. Structural brain alterations at different stages of schizophrenia: a voxel-based morphometric study. Schizophr. Res. 104 (2008) 44-60
41. Mendrek A., Kiehl K.A., Smith A.M., Irwin D., Forster B.B., and Liddle P.F. Dysfunction of a distributed neural circuitry in schizophrenia patients during a working-memory performance. Psychol. Med. 35 (2005) 187-196
42. Nakamura M., Nestor P.G., Levitt J.J., Cohen A.S., Kawashima T., Shenton M.E., and McCarley R.W. Orbitofrontal volume deficit in schizophrenia and thought disorder. Brain 131 (2008) 180-195
43. Navari S., and Dazzan P. Do antipsychotic drugs affect brain structure? A systematic and critical review of MRI findings. Psychol. Med. 2 (2009) 1-15
44. Pantelis C., Velakoulis D., McGorry P.D., Wood S.J., Suckling J., Phillips L.J., Yung A.R., Bullmore E.T., Brewer W., Soulsby B., Desmond P., and McGuire P.K. Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison. Lancet 361 (2003) 281-288
45. Pressler M., Nopoulos P., Ho B.C., and Andreasen N.C. Insular cortex abnormalities in schizophrenia: relationship to symptoms and typical neuroleptic exposure. Biol. Psychiatry 57 (2005) 394-398
46. Puri B.K., Hutton S.B., Saeed N., Oatridge A., Hajnal J.V., Duncan L., Chapman M.J., Barnes T.R., Bydder G.M., and Joyce E.M. A serial longitudinal quantitative MRI study of cerebral changes in first-episode schizophrenia using image segmentation and subvoxel registration. Psychiatry Res. 106 2 (2001) 141-150
47. Quickfall J., and Crockford D. Brain neuroimaging in cannabis use: a review. J. Neuropsychiatry Clin. Neurosci. 18 (2006) 318-332
48. Rais M., Cahn W., Van H.N., Schnack H., Caspers E., Hulshoff P.H., and Kahn R. Excessive brain volume loss over time in cannabis-using first-episode schizophrenia patients. Am. J. Psychiatry 165 (2008) 490-496
49. Salisbury, Kuroki N., Kasai K., Shenton M.E., and McCarley R.W. Progressive and interrelated functional and structural evidence of post-onset brain reduction in schizophrenia. Arch. Gen. Psychiatry 64 (2007) 521-529
50. Schlosser R., Gesierich T., Kaufmann B., Vucurevic G., Hunsche S., Gawehn J., and Stoeter P. Altered effective connectivity during working memory performance in schizophrenia: a study with fMRI and structural equation modeling. Neuroimage. 19 (2003) 751-763
51. Shenton M.E., Dickey C.C., Frumin M., and McCarley R.W. A review of MRI findings in schizophrenia. Schizophr. Res. 15 49(1-2) (2001) 1-52
52. Thompson P.M., Vidal C., Giedd J.N., Gochman P., Blumenthal J., Nicolson R., Toga A.W., and Rapoport J.L. Mapping adolescent brain change reveals dynamic wave of accelerated gray matter loss in very early-onset schizophrenia. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 11650-11655
53. van Haren N.E., Cahn W., Hulshoff Pol H.E., and Kahn R.S. Schizophrenia as a progressive brain disease. Eur. Psychiatr. 23 (2008) 245-254
54. Vita A., De P.L., Silenzi C., and Dieci M. Brain morphology in first-episode schizophrenia: a meta-analysis of quantitative magnetic resonance imaging studies. Schizophr. Res. 82 (2006) 75-88
55. Wakade C.G., Mahadik S.P., Waller J.L., and Chiu F.C. Atypical neuroleptics stimulate neurogenesis in adult rat brain. J. Neurosci. Res. 69 (2002) 72-79
56. Wang H.D., Dunnavant F.D., Jarman T., and Deutch A.Y. Effects of antipsychotic drugs on neurogenesis in the forebrain of the adult rat. Neuropsychopharmacology 29 (2004) 1230-1238
57. Weinberger D.R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psychiatry 44 (1987) 660-669
58. Whitworth A.B., Kemmler G., Honeder M., Kremser C., Felber S., Hausmann A., Walch T., Wanko C., Weiss E.M., Stuppaeck C.H., and Fleischhacker W.W. Longitudinal volumetric MRI study in first- and multiple-episode male schizophrenia patients. Psychiatry Res. 140 (2005) 225-237
59. Wood S.J., Velakoulis D., Smith D.J., Bond D., Stuart G.W., McGorry P.D., Brewer W.J., Bridle N., Eritaia J., Desmond P., Singh B., Copolov D., and Pantelis C. A longitudinal study of hippocampal volume in first episode psychosis and chronic schizophrenia. Schizophr. Res. 1 52(1-2) (2001) 37-46