Determination of the crystallinity of cephalexin in pharmaceutical formulations by chemometrical near-infrared spectroscopy

Drug Development and Industrial Pharmacy

Volumn 36, Issue 1, 2010, Pages 72-80

  Fukui, Yuya ^a   Otsuka, Makoto ^b  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b MUSASHINO UNIVERSITY   (Japan)

Author keywords

Amorphous solid; Cephalexin; Chemometrics; Crystallinity; Microcrystalline cellulose; Near infrared reflectance spectroscopy; Principal component regression

Indexed keywords

CARBOXYL GROUP; CEFALEXIN; FUNCTIONAL GROUP; METHYL GROUP; MICROCRYSTALLINE CELLULOSE;

ARTICLE; CHEMICAL BINDING; CRYSTAL STRUCTURE; DRUG CRYSTALLINITY; DRUG FORMULATION; DRUG STRUCTURE; HYDROGEN BOND; MOLECULAR INTERACTION; NEAR INFRARED SPECTROSCOPY; X RAY DIFFRACTION; X RAY POWDER DIFFRACTION;

ANTI-BACTERIAL AGENTS; CELLULOSE; CEPHALEXIN; CRYSTALLIZATION; EXCIPIENTS; HYDROGEN BONDING; POWDERS; PRINCIPAL COMPONENT ANALYSIS; SPECTROSCOPY, NEAR-INFRARED; X-RAY DIFFRACTION;

EID: 74949113937     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639040903092327     Document Type: Article

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