Anti-inflammatory function of withangulatin a by targeted inhibiting COX-2 expression via MAPK and NF-κB pathways

Journal of Cellular Biochemistry

Volumn 109, Issue 3, 2010, Pages 532-541

  Sun, Lijuan ^a   Liu, Jianwen ^a   Cui, Daling ^a   Li, Jiyu ^b   Yu, Youjun ^a   Lei, Ma ^a   Hu, Lihong ^c  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Anti inflammatory; COX 2; MAPK; NF B; Withangulatin A

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GAMMA INTERFERON; HERBACEOUS AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; WITHANGULATIN A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; EAR DISEASE; INFLAMMATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PHYSALIS; PHYSALIS ANGULATA; PLANT ROOT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SWELLING; T LYMPHOCYTE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INFLAMMATION; INTERLEUKIN-2; INTERLEUKIN-6; MALE; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PREGNENES; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

MUS; PHYSALIS ANGULATA;

EID: 74949103164     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22430     Document Type: Article

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