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ChemMedChem

Volumn 5, Issue 1, 2010, Pages 61-64

Inhibitors of cathepsins K and S identified using the DynaMAD virtual screening algorithm

(6) Stumpfe, Dagmar a Sisay, Mihiret T a Frizler, Maxim a Vogt, Ingo a,b Gütschow, Michael a Bajorath, Jürgen a

a UNIVERSITY OF BONN (Germany)

b UNIVERSITAT POMPEU FABRA (Spain)

Author keywords

Cathepsins; Cysteine proteases; Inhibitors; Mapping algorithms; Molecular similarity; Virtual screening

Indexed keywords

CATHEPSIN K INHIBITOR; CATHEPSIN S INHIBITOR;

ALGORITHM; ARTICLE; DRUG IDENTIFICATION; DRUG INHIBITION; DRUG SCREENING; IC 50; PRIORITY JOURNAL; VIRTUAL REALITY;

ALGORITHMS; CATHEPSIN K; CATHEPSINS; CYSTEINE PROTEINASE INHIBITORS; DATABASES, FACTUAL; SOFTWARE;

EID: 74849122037 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200900457 Document Type: Article

Times cited : (5)

References (33)

1
- 0036835460
- J. Bajorath, Nat. Rev. Drug Discovery 2002, 1, 882-894.
- (2002) Nat. Rev. Drug Discovery , vol.1 , pp. 882-894
- Bajorath, J.¹

2
- 11144222535
- R. D. Cramer, R. J. Jilek, S. Guessregen, S. J. Clark, B. Wendt, R. D. Clark, J. Med. Chem. 2004, 47, 6777-6791.
- (2004) J. Med. Chem , vol.47 , pp. 6777-6791
- Cramer, R.D.¹ Jilek, R.J.² Guessregen, S.³ Clark, S.J.⁴ Wendt, B.⁵ Clark, R.D.⁶

3
- 0037810410
- D. K. Nägler, R. Ménard, Biol. Chem. 2003, 384, 837-843.
- (2003) Biol. Chem , vol.384 , pp. 837-843
- Nägler, D.K.¹ Ménard, R.²

4
- 0035986223
- D. Brämme, J. Kaleta, Curr. Pharm. Des. 2002, 8, 1639-1658.
- (2002) Curr. Pharm. Des , vol.8 , pp. 1639-1658
- Brämme, D.¹ Kaleta, J.²

5
- 18944365919
- Y. Yasuda, J. Kaleta, D. Brömme, Adv. Drug Delivery Rev. 2005, 57, 973-993.
- (2005) Adv. Drug Delivery Rev , vol.57 , pp. 973-993
- Yasuda, Y.¹ Kaleta, J.² Brömme, D.³

6
- 1842581507
- B. R. Troen, Drug News Perspect. 2004, 17, 19-28.
- (2004) Drug News Perspect , vol.17 , pp. 19-28
- Troen, B.R.¹

7
- 1642433325
- H. C. Blair, N. A. Athanasou, Histol. Histopathol. 2004, 19, 189-199.
- (2004) Histol. Histopathol , vol.19 , pp. 189-199
- Blair, H.C.¹ Athanasou, N.A.²

8
- 60849134818
- Q. Zhao, Y, Jia, Y. Xiao, Biochem. Biophys. Res. Commun. 2009, 380, 721- 723.
- (2009) Biochem. Biophys. Res. Commun , vol.380 , pp. 721-723
- Zhao, Q.¹ Jia, Y.² Xiao, Y.³

9
- 37549068912
- S. Stoch, J. Wagner, Clin. Pharmacol. Ther. 2008, 83, 172-176.
- (2008) Clin. Pharmacol. Ther , vol.83 , pp. 172-176
- Stoch, S.¹ Wagner, J.²

10
- 0033571691
- C. Driessen, R. A. R. Bryant, A.-M. Lennon-Duménil, J. A. Villadangos, P. W. Bryant, G.-P. Shi, H. A. Chapman, H. L. Ploegh, J. Cell Biol. 1999, 147, 775-790.
- (1999) J. Cell Biol , vol.147 , pp. 775-790
- Driessen, C.¹ Bryant, R.A.R.² Lennon-Duménil, A.-M.³ Villadangos, J.A.⁴ Bryant, P.W.⁵ Shi, G.-P.⁶ Chapman, H.A.⁷ Ploegh, H.L.⁸

11
- 0037805704
- K. Honey, A. Y. Rudensky, Nat. Rev. Immunol. 2003, 3, 472-482.
- (2003) Nat. Rev. Immunol , vol.3 , pp. 472-482
- Honey, K.¹ Rudensky, A.Y.²

12
- 0037810382
- N. Katunuma, Y. Matsunaga, K. Himeno, Y. Hayashi, Biol. Chem. 2003, 384, 883-890.
- (2003) Biol. Chem , vol.384 , pp. 883-890
- Katunuma, N.¹ Matsunaga, Y.² Himeno, K.³ Hayashi, Y.⁴

13
- 33748753263
- S. Taleb, R. Cancello, K. Clement, D. Lacasa, Endocrinology 2006, 147, 4950-4959.
- (2006) Endocrinology , vol.147 , pp. 4950-4959
- Taleb, S.¹ Cancello, R.² Clement, K.³ Lacasa, D.⁴

14
- 33646058296
- R. Leung-Toung, Y. Zhao, W. Li, T. F. Tam, K. Karimian, M. Spino, Curr. Med. Chem. 2006, 13, 547-581.
- (2006) Curr. Med. Chem , vol.13 , pp. 547-581
- Leung-Toung, R.¹ Zhao, Y.² Li, W.³ Tam, T.F.⁴ Karimian, K.⁵ Spino, M.⁶

15
- 58549115294
- D. Stumpfe, M. Frizler, M. T. Sisay, J. Batista, I. Vogt, M. Gütschow, J. Bajorath, ChemMedChem 2009, 4, 52-54.
- (2009) ChemMedChem , vol.4 , pp. 52-54
- Stumpfe, D.¹ Frizler, M.² Sisay, M.T.³ Batista, J.⁴ Vogt, I.⁵ Gütschow, M.⁶ Bajorath, J.⁷

16
- 52049118326
- P. Markt, C. McGoohan, B. Walker, J. Kirchmair, C. Feldmann, G. De Martino, G. Spitzer, S. Distinto, D. Schuster, G. Wolber, C. Laggner, T. Langer, J. Chem. Inf. Model. 2008, 48, 1693-1705.
- (2008) J. Chem. Inf. Model , vol.48 , pp. 1693-1705
- Markt, P.¹ McGoohan, C.² Walker, B.³ Kirchmair, J.⁴ Feldmann, C.⁵ De Martino, G.⁶ Spitzer, G.⁷ Distinto, S.⁸ Schuster, D.⁹ Wolber, G.¹⁰ Laggner, C.¹¹ Langer, T.¹²

17
- 45449120863
- M. Ravikumar, S. Pavan, S. Bairy, A. Pramod, M. Sumakanth, M. Kishore, T. Sumithra, Chem. Biol. Drug Des. 2008, 72, 79-90.
- (2008) Chem. Biol. Drug Des , vol.72 , pp. 79-90
- Ravikumar, M.¹ Pavan, S.² Bairy, S.³ Pramod, A.⁴ Sumakanth, M.⁵ Kishore, M.⁶ Sumithra, T.⁷

18
- 28144443719
- R. Löser, K. Schilling, E. Dimmig, M. Gütschow, J. Med. Chem. 2005, 48, 7688 -7707.
- (2005) J. Med. Chem , vol.48 , pp. 7688-7707
- Löser, R.¹ Schilling, K.² Dimmig, E.³ Gütschow, M.⁴

19
- 74849131110
- R. Löser, M. Frizler, K. Schilling, M. Gütschow, Angew. Chem. 2008, 120, 4403-4406;
- (2008) Angew. Chem , vol.120 , pp. 4403-4406
- Löser, R.¹ Frizler, M.² Schilling, K.³ Gütschow, M.⁴

20
- 46749119861
- Angew. Chem. Int. Ed. 2008, 47, 4331-4334.
- (2008) Angew. Chem. Int. Ed , vol.47 , pp. 4331-4334

21
- 33846640469
- R. M. Oballa, J.-F. Truchon, C. I. Bayly, N. Chauret, S. Day, S. Crane, C. Berthelette, Bioorg. Med. Chem. Lett. 2007, 17, 998-1002.
- (2007) Bioorg. Med. Chem. Lett , vol.17 , pp. 998-1002
- Oballa, R.M.¹ Truchon, J.-F.² Bayly, C.I.³ Chauret, N.⁴ Day, S.⁵ Crane, S.⁶ Berthelette, C.⁷

22
- 59849088616
- P. A. MacFaul, A. D. Morley, J. J. Crawford, Bioorg. Med. Chem. Lett. 2009, 19, 1136-1138.
- (2009) Bioorg. Med. Chem. Lett , vol.19 , pp. 1136-1138
- MacFaul, P.A.¹ Morley, A.D.² Crawford, J.J.³

23
- 33144476158
- D. C. Tully, H. Liu, P. B. Alper, A. K. Chatterjee, R. Epple, M. J. Roberts, J. A. Williams, K. T. Nguyen, D. H. Woodmansee, C. Tumanut, J. Li, G. Spraggon, J. Chang, T. Tuntland, J. L. Harris, D. S. Karanewsky, Bioorg. Med. Chem. Lett. 2006, 16, 1975-1980.
- (2006) Bioorg. Med. Chem. Lett , vol.16 , pp. 1975-1980
- Tully, D.C.¹ Liu, H.² Alper, P.B.³ Chatterjee, A.K.⁴ Epple, R.⁵ Roberts, M.J.⁶ Williams, J.A.⁷ Nguyen, K.T.⁸ Woodmansee, D.H.⁹ Tumanut, C.¹⁰ Li, J.¹¹ Spraggon, G.¹² Chang, J.¹³ Tuntland, T.¹⁴ Harris, J.L.¹⁵ Karanewsky, D.S.¹⁶

24
- 20044390727
- D. J. Gustin, C. A. Sehon, J. Wei, H. Cai, S. P. Meduna, H. Khatuya, S. Sun, Y. Gu, W. Jiang, R. L. Thurmond, L. Karlsson, J. P. Edwards, Bioorg. Med. Chem. Lett. 2005, 15, 1687-1691.
- (2005) Bioorg. Med. Chem. Lett , vol.15 , pp. 1687-1691
- Gustin, D.J.¹ Sehon, C.A.² Wei, J.³ Cai, H.⁴ Meduna, S.P.⁵ Khatuya, H.⁶ Sun, S.⁷ Gu, Y.⁸ Jiang, W.⁹ Thurmond, R.L.¹⁰ Karlsson, L.¹¹ Edwards, J.P.¹²

25
- 46049100613
- J. Batista, J. Bajorath, ChemMedChem 2008, 3, 67-73.
- (2008) ChemMedChem , vol.3 , pp. 67-73
- Batista, J.¹ Bajorath, J.²

26
- 33746883889
- H. Eckert, I. Vogt, J. Bajorath, J. Chem. Inf. Model. 2006, 46, 1623-1634.
- (2006) J. Chem. Inf. Model , vol.46 , pp. 1623-1634
- Eckert, H.¹ Vogt, I.² Bajorath, J.³

27
- 13844312649
- J. J. Irwin, B. K. Shoichet, J. Chem. Inf. Model. 2005, 45, 177-182.
- (2005) J. Chem. Inf. Model , vol.45 , pp. 177-182
- Irwin, J.J.¹ Shoichet, B.K.²

28
- 84885379370
- accessed November 30, 2009
- MACCS Structural Keys: San Leandro, CA (USA), MDL Elsevier, http://www.mdl.com (accessed November 30, 2009).
- MACCS Structural Keys: San Leandro, CA (USA), MDL Elsevier

29
- 21244468757
- P. Willett, J. Med. Chem. 2005, 48, 4183-4199.
- (2005) J. Med. Chem , vol.48 , pp. 4183-4199
- Willett, P.¹

30
- 84885370361
- Molecular Operating Environment (MOE) version 2007.09: Chemical Computing Group, Inc, 2007, Montreal Canada
- Molecular Operating Environment (MOE) version 2007.09: Chemical Computing Group, Inc., 2007, Montreal (Canada).

31
- 11144323163
- B. K. Shoichet, Nature 2004, 432, 862-865.
- (2004) Nature , vol.432 , pp. 862-865
- Shoichet, B.K.¹

32
- 0037068532
- Y. Martin, J. Kofron, L. Traphagen, J. Med. Chem. 2002, 45, 4350-4358.
- (2002) J. Med. Chem , vol.45 , pp. 4350-4358
- Martin, Y.¹ Kofron, J.² Traphagen, L.³

33
- 33747373128
- D. C. Tully, H. Liu, A. K. Chatterjee, P. B. Alper, R. Epple, J. A. Williams, M. J. Roberts, D. H. Woodmansee, B. T. Masick, C. Tumanut, J. Li, G. Spraggon, M. Hornsby, J. Chang, T. Tuntland, T. Hollenbeck, P. Gordon, J. L. Harris, D. S. Karanewsky, Bioorg. Med. Chem. Lett. 2006, 16, 5112-5117.
- (2006) Bioorg. Med. Chem. Lett , vol.16 , pp. 5112-5117
- Tully, D.C.¹ Liu, H.² Chatterjee, A.K.³ Alper, P.B.⁴ Epple, R.⁵ Williams, J.A.⁶ Roberts, M.J.⁷ Woodmansee, D.H.⁸ Masick, B.T.⁹ Tumanut, C.¹⁰ Li, J.¹¹ Spraggon, G.¹² Hornsby, M.¹³ Chang, J.¹⁴ Tuntland, T.¹⁵ Hollenbeck, T.¹⁶ Gordon, P.¹⁷ Harris, J.L.¹⁸ Karanewsky, D.S.¹⁹

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