Clinical features of antinuclear antibody-positive patients with atopic dermatitis

Journal of Nippon Medical School

Volumn 76, Issue 6, 2009, Pages 300-307

  Higashi, Naoyuki ^a,b   Niimi, Yayoi ^a   Aoki, Mikako ^a   Kawana, Seiji ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b NIPPON MEDICAL SCHOOL TAMA NAGAYAMA HOSPITAL   (Japan)

Author keywords

Antinuclear antibodies; Atopic dermatitis; Basophils; Disease severity; Photosensitivity

Indexed keywords

ANTINUCLEAR ANTIBODY; IMMUNOGLOBULIN E; LACTATE DEHYDROGENASE;

ADOLESCENT; ADULT; ARTICLE; ATOPIC DERMATITIS; BASOPHIL; CELL COUNT; CHILD; CLINICAL FEATURE; DISEASE SEVERITY; FEMALE; HEP 2 CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LACTATE DEHYDROGENASE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PHOTOSENSITIVITY; PRESCHOOL CHILD; PREVALENCE; SCHOOL CHILD;

ADOLESCENT; ADULT; ANTIBODIES, ANTINUCLEAR; CHILD; CHILD, PRESCHOOL; DERMATITIS, ATOPIC; FEMALE; HUMANS; L-LACTATE DEHYDROGENASE; MALE; MIDDLE AGED; PHOTOSENSITIVITY DISORDERS;

EID: 74849114301     PISSN: 13454676     EISSN: 13473409     Source Type: Journal    
DOI: 10.1272/jnms.76.300     Document Type: Article

References (34)

1. Hanifin JM, Rajka G: Diagnostic features of atopic dermatitis. Acta Derm Venereol (Stockh) 1980; 92 (Suppl.): 44-47.
2. Nawata Y, Koike T, Hosokawa K, et al.: Anti-IgE autoantibody in patients with atopic dermatitis. J Immunol 1985; 135: 478-482.
3. Quinti I, Brozek C, Wood N, et al.: Circulating IgG autoantibodies to IgE in atopic syndromes. J Allergy Clin Immunol 1986; 77: 586-594.
4. Valenta R, Seiberler S, Natter S, et al.: Autoallergy: a pathogenetic factor in atopic dermatitis? J Allergy Clin Immunol 2000; 105: 432-437.
5. Ohkouchi K, Mizutani H, Tanaka M, et al.: Anti-elongation factor-1alpha autoantibody in adult atopic dermatitis patients. Int Immunol 1999; 11: 1635-1640.
6. Ochs RL, Muro Y, Si Y, et al.: Autoantibodies to DFS 70 kd/transcription coactivator p75 in atopic dermatitis and other conditions. J Allergy Clin Immunol 2000; 105: 1211-1220.
7. Valenta R, Natter S, Seiberler S, et al.: Molecular characterization of an autoallergen, Hom s 1, identified by serum IgE from atopic dermatitis patients. J Invest Dermatol 1998; 111: 1178-1183.
8. Natter S, Seiberler S, Hufnagl P, et al.: Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients. FASEB J 1998; 12: 1559-1569.
9. Taniguchi Y, Yamakami A, Sakamoto T, et al.: Positive antinuclear antibody in atopic dermatitis. Acta Derm Venereol (Stockh) 1992; 176 (Suppl.): 62-64.
10. Tada J, Toi Y, Yoshioka T, et al.: Antinuclear antibodies in patients with atopic dermatitis and severe facial lesions. Dermatology 1994; 189: 38-40.
11. Matsumura Y, Furukawa F, Ikai K, et al.: Evaluation of anti-nuclear antibody in adult atopic dermatitis. Acta Dermatol-Kyoto 1994; 89: 53-56.
12. Rajka G, Langeland T: Grading of the severity of atopic dermatitis. Acta Derm Venereol 1989; 144: 13-14.
13. Sanda T, Matsumoto Y, Ohashi M, et al.: Antinuclear antibodies in atopic dermatitis patients. Jpn J Dermatol 1992; 102: 505-508 (Japanese).
14. Ginel PJ, Lucena R: Investigation of antinuclear antibodies in canine atopic dermatitis. J Vet Med A Physiol Pathol Clin Med 2001; 48: 193-198.
15. Higashi N, Kawana S: Atopic eczema complicated by systemic lupus erythematosus. Eur J Dermatol 2005; 15: 500-502.
16. Arbuckle MR, McClain MT, Rubertone MV, et al.: Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003; 349: 1526-1533.
17. Krutmann J: Phototherapy for atopic dermatitis. Clin Exp Dermatol 2000; 25: 552-558.
18. Mukai H, Noguchi T, Kamimura K, et al.: Significance of elevated serum LDH (lactate dehydrogenase) activity in atopic dermatitis. J Dermatol 1990; 17: 477-481.
19. Kagi MK, Joller-Jemelka H, Wuthrich B: Correlation of eosinophils, eosinophil cationic protein and soluble interleukin-2 receptor with the clinical activity of atopic dermatitis. Dermatology 1992; 185: 88-92.
20. Oettgen HC, Geha RS: IgE in asthma and atopy: cellular and molecular connections. J Clin Invest 1999; 104: 829-835.
21. Turner H, Kinet JP: Signaling through the high-affinity IgE receptor Fc epsilonRI. Nature 1999; 402: B24-30.
22. Falcone FH, Hass H, Gibbs BF: The human basophil: a new appreciation of its role in immune responses. Blood 2000; 96: 4028-4038.
23. Arock M, Merle-Beral H, Dugas B, et al.: IL-4 release by human leukemic and activated normal basophils. J Immunol 1993; 151: 1441-1447.
24. Li H, Sim TC, Alam R: IL-13 released by and localized in human basophils. J Immunol l996; 156: 4833-4838.
25. Ochensberger B, Daepp GC, Rihs S, et al.: Human blood basophils produce interleukin-13 in response to IgE-receptor-dependent and -independent activation. Blood 1996; 88: 3028-3037.
26. Mukai K, Matsuoka K, Suzuki H, et al.: Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells. Immunity 2005; 23: 191-202.
27. Hooper B, Whittingham S, Mathews JD, et al.: Autoimmunity in a rural community. Clin Exp Immunol 1972; 12: 79-87.
28. Szakos E, Lakos G, Aleksza M, et al.: Relationship between skin bacterial colonization and the occurrence of allergen-specific and non-allergen-specific antibodies in sera of children with atopic eczema/dermatitis syndrome. Acta Derm Venereol 2004; 84: 32-36.
29. Valverde E, Vich JM, Huguet J, et al.: An in vitro study of lymphocytes in patients with atopic dermatitis. Clin Allergy 1983; 13: 81-88.
30. Becker KG, Barnes KC: Underlying disease specificity of genetic loci in atopic dermatitis. J Invest Dermatol 2001; 117: 1325-1327.
31. Ambrozic A, Avicin T, Ichikawa K, et al.: Anti-betA (2)-glycoprotein I antibodies in children with atopic dermatitis. Int Immunol 2002; 14: 823-830.
32. Szakos E, Lakos G, Aleksza M, et al.: Association between the occurrence of the anticardiolipin IgM and mite allergen-specific IgE antibodies in children with extrinsic type of atopic eczema/dermatitis syndrome. Allergy 2004; 59: 164-167.
33. Kokkonen J, Niinimaki A: Increased incidence of autoimmune disorders as a late complication in children with early onset dermatitis and/or milk allergy. J Autoimmun 2004; 22: 341-344.
34. Ricci G, Maldini MC, Patrizi A, et al.: Anticardiolipin antibodies in children with atopic dermatitis. J Autoimmun 2005; 24: 221-225.