Chemo-enzymatic transformation of taxanes and their reversal activity towards MDR tumor cells

Current Topics in Medicinal Chemistry

Volumn 9, Issue 17, 2009, Pages 1625-1635

  Dai, Jungui ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Chemical transformation; Enzymatic transformation; MDR tumor cells; Reversal activity; Taxane

Indexed keywords

7BETA HYDROXYLASE; 9ALPHA HYDROXYLASE; BETA CYCLODEXTRIN; CARBENE; ETHYLENE OXIDE; OXETANE DERIVATIVE; OXYGENASE; PACLITAXEL; SINENXAN A; TAXANE DERIVATIVE; UNCLASSIFIED DRUG; VERAPAMIL; VINCRISTINE;

ABSIDIA; ABSIDIA COERULEA; ACYLATION; ALKYLATION; ANTINEOPLASTIC ACTIVITY; ASPARAGUS; CANCER CELL CULTURE; DERIVATIZATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TRANSFORMATION; ENZYME SPECIFICITY; EPOXIDATION; GINKGO BILOBA; GLYCOSYLATION; HUMAN; HYDROLYSIS; HYDROXYLATION; MULTIDRUG RESISTANCE; NONHUMAN; PLANT CELL; PLANT CELL CULTURE; PLATYCODON; REACTION ANALYSIS; REVIEW; TAXUS; TAXUS CHINENSIS;

ANIMALS; BIOLOGICAL PRODUCTS; CELL PROLIFERATION; DRUG RESISTANCE, MULTIPLE; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR CONFORMATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TAXOIDS; TAXUS; TUMOR CELLS, CULTURED;

EID: 74749107324     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802609789941924     Document Type: Review

References (17)

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