Biotransformation and tumor multidrug resistance reversal potency of polyoxygenated taxadienes

Journal of Molecular Catalysis B: Enzymatic

Volumn 55, Issue 1-2, 2008, Pages 12-18

  Zou, Jian Hua ^a,b,c   Du, Huixia ^a   Zhang, Yi ^a   Dai, Jungui ^a,b,c   Yin, Dali ^a   Chen, Xiaoguang ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c BEIJING HOSPITAL   (China)

Author keywords

Biotransformation; Ginkgo biloba; Taxadienes; Tumor MDR reversal agents

Indexed keywords

BIOLOGICAL ORGANS; CELL CULTURE; HEALTH; KETONES; METABOLITES; STABILIZERS (AGENTS);

ADENOCARCINOMA CELL LINE; CULTURED CELLS; ELSEVIER (CO); GINKGO BILOBA; HYDROXYL GROUPS; METHOXY; METHOXYL GROUPS; MULTIDRUG RESISTANCE (MDR); NON-SMALL CELL LUNG CANCER (NSCLC); PHARMACOPHORES; TAXADIENE;

BIOMOLECULES;

10BETA HYDROXY 2ALPHA,5ALPHA,9ALPHA TRIACETOXYTAXA 4(20),11(12) DIEN 13 ONE; 10BETA METHOXY 2ALPHA,5ALPHA,14BETA TRIACETOXYTAXA 4(20),11(12) DIENE; 2 ALPHA,5ALPHA DIACETOXY 10BETA,14BETA DIHYDROXYTAXA 4(20),11(12) DIENE; 2ALPHA ACETOXY 5ALPHA,14BETA DIHYDROXY 10BETA METHOXYTAXA 4(20),11(12) DIENE; 2ALPHA,5ALPHA DIACETOXY 10BETA METHOXYTAXA 4(20),11(12) DIEN 13 ONE; 2ALPHA,5ALPHA DIACETOXY 14BETA HYDROXY 10BETA METHOXYTAXA 4(20),11(12) DIENE; 2ALPHA,5ALPHA DIACETOXY 9' HYDROXY 10BETA METHOXYTAXA 4(20),11(12) DIEN 13 ONE; 2ALPHA,5ALPHA DIACETOXY 9ALPHA,10BETA,14BETA TRIHYDROXYTAXA 4(20),11(12) DIENE; 2ALPHA,5ALPHA DIACETOXY 9ALPHA,14BETA DIHYDROXY 10BETA METHOXYTAXA 4(20),11(12) DIENE; 2ALPHA,5ALPHA,10BETA TRIACETOXY 3,11 CYCLOTAXA 4(20) EN 13 ONE; 2ALPHA,5ALPHA,10BETA TRIACETOXY 4BETA,20 EPOXYTAXA 11(12) EN 13 ONE; 2ALPHA,5ALPHA,10BETA TRIACETOXYTAXA 4(20),11(12) DIEN 13 ONE; 9ALPHA HYDROXY 10BETA METHOXY 2ALPHA,5ALPHA,14BETA TRIACETOXYTAXA 4(20),11(12) DIENE; 9ALPHA HYDROXY 2ALPHA,5ALPHA,10BETA TRIACETOXYTAXA 4(20),11(12) DIEN 13 ONE; HYDROXYL GROUP; PACLITAXEL; TAXANE DERIVATIVE; UNCLASSIFIED DRUG; VERAPAMIL;

ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CULTURE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TRANSFORMATION; GINKGO BILOBA; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; MULTIDRUG RESISTANCE; NONHUMAN; PHARMACOPHORE; PROTON NUCLEAR MAGNETIC RESONANCE; TUMOR RESISTANCE;

GINKGO BILOBA;

EID: 47949106352     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcatb.2008.01.005     Document Type: Article

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