L-lysine pro-prodrug containing trans-ferulic acid for 5-amino salicylic acid colon delivery: Synthesis, characterization and in vitro antioxidant activity evaluation

Chemical and Pharmaceutical Bulletin

Volumn 58, Issue 1, 2010, Pages 103-105

  Cassano, Roberta ^a   Trombino, Sonia ^a   Cilea, Alessia ^a   Ferrarelli, Teresa ^a   Muzzalupo, Rita ^a   Picci, Nevio ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

Author keywords

5 Amino salicylic acid; Colon specific; L lysine; Pro prodrug; trans ferulic acid

Indexed keywords

2,2' AZOBIS(2 AMIDINOPROPANE); 5 AMINO SALICYLIC ACID; FERULIC ACID; LIPID; LYSINE; METHANOL; SALICYLIC ACID DERIVATIVE; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG;

AMIDATION; ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CHEMICAL REACTION; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG INHIBITION; DRUG SYNTHESIS; ENTERITIS; GAS CHROMATOGRAPHY; IN VITRO STUDY; INFRARED SPECTROSCOPY; LIPID PEROXIDATION; MASS SPECTROMETRY; MICROSOME MEMBRANE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT;

ANIMALS; ANTIOXIDANTS; COLON; COUMARIC ACIDS; LIPID PEROXIDATION; LYSINE; MESALAMINE; MICROSOMES, LIVER; PRODRUGS; RATS;

EID: 74749085408     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.58.103     Document Type: Article

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