Mutual azo prodrug of 5-aminosalicylic acid for colon targeted drug delivery: Synthesis, kinetic studies and pharmacological evaluation

Indian Journal of Pharmaceutical Sciences

Volumn 68, Issue 2, 2006, Pages 171-178

  Nagpal, Deepika ^a   Singh, R ^a   Gairola, Neha ^a   Bodhankar, S ^a   Dhaneshwar, Suneela ^a  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCHLORIC ACID; MESALAZINE; PHOSPHATE BUFFERED SALINE; PRODRUG; SALAZOSULFAPYRIDINE; SALICYLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLD STRESS; COLON MUCOSA; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG EXCRETION; DRUG HALF LIFE; DRUG RELEASE; DRUG SYNTHESIS; DRUG TARGETING; FEMALE; FIRST PASS EFFECT; IN VITRO STUDY; MALE; NONHUMAN; PH MEASUREMENT; RAT; ULCERATIVE COLITIS; ULCEROGENESIS;

EID: 33745176198     PISSN: 0250474X     EISSN: None     Source Type: Journal    
DOI: 10.4103/0250-474x.25710     Document Type: Article

References (18)

1. Chourasia, M.K. and Jam, S.K., J. Pharm. Sci., 2003, 6, 33.
2. Azad Khan, A.K., Truelove, S.C. and Aronseq, J.K., Brit. J. Clin. Pharmacol., 1982, 13, 523.
3. Chan, R.P., Pope, D.J., Gilbert, A.P., Baron, J.H. and Lennard-Jones, J.P., Dig. Dis. Sci., 1983, 28, 609.
4. Rao, S.S.C., Read, N.W. and Holdsworth, C.D., Gut, 1987, 28, 1474.
5. Pamucku, R., Hanauer, S. and Chang, E.B., Gastroenterology, 1988, 95, 975.
6. McIntyre, P.B., Rodrigues, C.A. and Lennard-Jones, J.E., Aliment. Pharmacol. Ther., 1988, 2, 237.
7. Takagi, K. and Okabe, S., US patent No., US 3,988466, 1976.
8. Neilsen, N. M. and Bundgaard, H., J. Med. Chem., 1989, 32, 727.
9. rd Edn., Wiely Eastern Ltd., U.S.A, 1986, 370.
10. th Edn., The English Language Book Society and Longman, U.K, 1978, 688.
11. www.organicsynthesis.com. (10/01/2004)
12. Neilsen, N.M. and Bundgaard, H., J. Med. Chem., 1988, 77, 285.
13. Uekama, K., Minami, K. and Hirayama, F., J. Med. Chem., 1997, 40, 190.
14. Rainsford, K.D., Proc. Brit. Pharmacol. Soc., 1980, 226 P.
15. Cioli, V., Putzolu, S., Rossi, V., Barcellona, P.S. and Corradino, C., Toxicol. Appl. Pharmacol., 1979, 50, 283.
16. Moris, G.P., Beck, P.L., Herridge, M.S., Drew, W.T., Szewczuk, M.R. and Wallace, J.L., Gastroenterology, 1989, 96, 795.
17. Zingarelli, B., Squadrito, F., Graziani, P., Camerini, R. and Caputi, A.P., Agents Actions, 1993, 39, 150.
18. Yamada, T., Marshall, S., Specian, R.D. and Grisham, M.B., Gastroenterology, 1992, 102, 1524.