메뉴 건너뛰기




Volumn 268, Issue 5-6, 2010, Pages 845-852

Friction in ultra-thin conjunction of valve seals of pressurised metered dose inhalers

Author keywords

Adhesion; Elastomeric seals; Friction; pMDI valve

Indexed keywords

AFM TIP; ASPERITY INTERACTIONS; COEFFICIENT OF FRICTIONS; COMPONENT LEVELS; DEVELOPED MODEL; DOMINANT MECHANISM; ELASTOMERIC SEALS; FRICTION GENERATION; FRICTION MODELS; FRICTION TEST; HYDRAULIC ACTUATOR; MANUFACTURING TOLERANCES; METERED-DOSE INHALERS; MODEL PREDICTION; MOVING INTERFACE; NANO SCALE; NITRILE RUBBERS; OTHER APPLICATIONS; POLYBUTYLENE TEREPHTHALATES; POTENTIAL PROBLEMS; PRESSURE CHANGE; PRODUCT PERFORMANCE; RUBBER SEALS; SLIDING SPEED; ULTRA-THIN; VISCOUS SHEAR;

EID: 74649084418     PISSN: 00431648     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.wear.2009.12.003     Document Type: Article
Times cited : (19)

References (22)
  • 1
    • 0033807450 scopus 로고    scopus 로고
    • CFC transition: the Emperor's new clothes. Each class of drug deserves a delivery system that meets its own requirements
    • Everard M.L. CFC transition: the Emperor's new clothes. Each class of drug deserves a delivery system that meets its own requirements. Thorax 55 (2000) 811-819
    • (2000) Thorax , vol.55 , pp. 811-819
    • Everard, M.L.1
  • 3
    • 74649084114 scopus 로고    scopus 로고
    • FDA, Guidance for industry metered dose inhaler (MDI) and dry powder inhaler (DPI) drug products, CDERGUID/2180dft.wpd. November 1998, http://www.fda.gov/cder/guidance/2180dft.pdf, 1998.
    • FDA, Guidance for industry metered dose inhaler (MDI) and dry powder inhaler (DPI) drug products, CDERGUID/2180dft.wpd. November 1998, http://www.fda.gov/cder/guidance/2180dft.pdf, 1998.
  • 6
    • 0003595302 scopus 로고    scopus 로고
    • Professional Engineering Publishing and SAE joint Publishers, London and Warrendale, PA
    • H. Rahnejat, Multi-body Dynamics: Vehicles, Machines and Mechanisms, Professional Engineering Publishing and SAE (joint Publishers), London and Warrendale, PA, 1998.
    • (1998) Multi-body Dynamics: Vehicles, Machines and Mechanisms
    • Rahnejat, H.1
  • 7
    • 0029926013 scopus 로고    scopus 로고
    • MDIs: physics of aerosol formulation
    • Clark A. MDIs: physics of aerosol formulation. J. Aerosol. Med. 9 (1996) S19-S26
    • (1996) J. Aerosol. Med. , vol.9
    • Clark, A.1
  • 9
    • 0023125011 scopus 로고
    • Hydrodynamics of rubber seals for reciprocating motion, lubricating film thickness, and out-leakage of O-seals
    • Karaszkiewicz A. Hydrodynamics of rubber seals for reciprocating motion, lubricating film thickness, and out-leakage of O-seals. Ind. Eng. Chem. Res. 26 (1987) 2180-2185
    • (1987) Ind. Eng. Chem. Res. , vol.26 , pp. 2180-2185
    • Karaszkiewicz, A.1
  • 10
    • 1642346362 scopus 로고    scopus 로고
    • Transient Elastohydrodynamic Lubrication of Rectangular Elastomeric Seals for Linear Hydraulic Actuators
    • Nikas G.K. Transient Elastohydrodynamic Lubrication of Rectangular Elastomeric Seals for Linear Hydraulic Actuators. Proc. Inst. Mech. Eng.; J. Eng. Trib. 217 (2003) 461-473
    • (2003) Proc. Inst. Mech. Eng.; J. Eng. Trib. , vol.217 , pp. 461-473
    • Nikas, G.K.1
  • 14
    • 74649084955 scopus 로고    scopus 로고
    • ® 134a pharma, HFA Propellants for Medical Use, Solvay Fluor and Derivative GmbH, Technical service, PO Box 220 30002, Hanover, Germany.
    • ® 134a pharma, HFA Propellants for Medical Use, Solvay Fluor and Derivative GmbH, Technical service, PO Box 220 30002, Hanover, Germany.
  • 15
    • 27144506683 scopus 로고
    • Pressure distributions beneath spherical and conical shapes pressed into a rubber plane, and their bearing on coefficients of friction under wet conditions
    • Sabey B.E. Pressure distributions beneath spherical and conical shapes pressed into a rubber plane, and their bearing on coefficients of friction under wet conditions. Proc. Phys. Soc. 71 B (1958) 979-980
    • (1958) Proc. Phys. Soc. , vol.71 , Issue.B , pp. 979-980
    • Sabey, B.E.1
  • 16
    • 0025508240 scopus 로고
    • Geometry and contact pressure of an O-ring mounted in a seal groove
    • Karaszkiewicz A. Geometry and contact pressure of an O-ring mounted in a seal groove. Ind. Eng. Chem. Res. 29 (1990) 2134-2137
    • (1990) Ind. Eng. Chem. Res. , vol.29 , pp. 2134-2137
    • Karaszkiewicz, A.1
  • 17
    • 0023116888 scopus 로고
    • Stress fields in a compressed unconstrained elastomeric O-ring seal and comparison of computer predictions with experimental results
    • BHRA British Hydromechanics Research Association, Cranfield Bedford, England, paper B1, pp
    • A.F. George, A. Strozzi, J.I. Rich, Stress fields in a compressed unconstrained elastomeric O-ring seal and comparison of computer predictions with experimental results, 11th International Conference on Fluid Sealing; BHRA (British Hydromechanics Research Association), Cranfield Bedford, England, 1987, paper B1, pp. 117-137.
    • (1987) 11th International Conference on Fluid Sealing , pp. 117-137
    • George, A.F.1    Strozzi, A.2    Rich, J.I.3
  • 18
    • 0018325980 scopus 로고
    • Calculation of the pressure distribution in an O-ring seal contact
    • The University of Leeds, England
    • Johannesson H. Calculation of the pressure distribution in an O-ring seal contact. 5th Leeds-Lyon Symposium on Tribology (1978), The University of Leeds, England
    • (1978) 5th Leeds-Lyon Symposium on Tribology
    • Johannesson, H.1
  • 19
    • 74649086237 scopus 로고    scopus 로고
    • Solkane refrigerants characteristics, version 2.009.99. CD ROM available from Solvay Fluor and Derivative GmbH, Technical service, PO Box 220 30002, Hanover, Germany
    • Solkane refrigerants characteristics, version 2.009.99. CD ROM available from Solvay Fluor and Derivative GmbH, Technical service, PO Box 220 30002, Hanover, Germany.
  • 20
    • 84976355631 scopus 로고    scopus 로고
    • Static friction and surface roughness studies of surface micromachined electrostatic micromotors using an atomic force/friction force microscope
    • Sundararajan S., and Bhushan B. Static friction and surface roughness studies of surface micromachined electrostatic micromotors using an atomic force/friction force microscope. J. Vac. Sci. Tech. A 19 (2001) 1777-1785
    • (2001) J. Vac. Sci. Tech. A , vol.19 , pp. 1777-1785
    • Sundararajan, S.1    Bhushan, B.2
  • 21
    • 34248156138 scopus 로고    scopus 로고
    • Biofilm cohesiveness measurement using a novel atomic force microscopy methodology
    • Ahimou F., Semmens M., Novak P., and Haugstad G. Biofilm cohesiveness measurement using a novel atomic force microscopy methodology. J. Appl. Environ. Microbiol. 73 9 (2007) 2897-2904
    • (2007) J. Appl. Environ. Microbiol. , vol.73 , Issue.9 , pp. 2897-2904
    • Ahimou, F.1    Semmens, M.2    Novak, P.3    Haugstad, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.