QT interval dispersion and cardiac sympathovagal balance shift in rats with acute ethanol withdrawal

Alcoholism: Clinical and Experimental Research

Volumn 34, Issue 2, 2010, Pages 223-230

  Shirafuji, Seiko ^a   Liu, Jinyao ^a   Okamura, Nanako ^a   Hamada, Kazuyuki ^a   Fujimiya, Tatsuya ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cardiac Sympathovagal Balance; Carvedilol; Ethanol; Myocardial Repolarization; QT Interval Dispersion

Indexed keywords

ALCOHOL; ALPHA ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CARVEDILOL;

ADRENERGIC RECEPTOR BLOCKING; ADRENERGIC SYSTEM; ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET; HEART INNERVATION; HEART RATE VARIABILITY; HEART REPOLARIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; QT DISPERSION; RAT; SYMPATHETIC INNERVATION; VAGUS TONE; WISTAR RAT;

ADRENERGIC ALPHA-ANTAGONISTS; ADRENERGIC BETA-ANTAGONISTS; ALCOHOL DRINKING; ANIMALS; CARBAZOLES; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ELECTROCARDIOGRAPHY; ELECTROLYTES; ETHANOL; HEART; HEMODYNAMICS; INFUSION PUMPS, IMPLANTABLE; LONG QT SYNDROME; MALE; PROPANOLAMINES; RATS; RATS, WISTAR; SINOATRIAL NODE; SUBSTANCE WITHDRAWAL SYNDROME; SYMPATHETIC NERVOUS SYSTEM; TELEMETRY; VAGUS NERVE;

RATTUS; RATTUS NORVEGICUS;

EID: 74549165416     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2009.01085.x     Document Type: Article

References (40)

1. Adamson PB, Huang MH, Vanoli E, Foreman RD, Schwartz PJ, Hull SS Jr. (1994) Unexpected interaction between β-adrenergic blockade and heart rate variability before and after myocardial infarction. A longitudinal study in dogs at high and low risk for sudden death. Circulation 90 : 976 982.
2. Anonymous (1996) Heart rate variability: standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 93 : 1043 1065.
3. Banerjee SP, Sharma VK, Khanna JM (1978) Alterations in beta-adrenergic receptor binding during ethanol withdrawal. Nature 276 : 407 409.
4. Barr CS, Naas AA, Fenwick M, Struthers AD (1997) Enalapril reduces QT dispersion in patients with mild congestive heart failure secondary to coronary artery disease. Am J Cardiol 79 : 328 333.
5. Barr CS, Naas A, Freeman M, Lang CC, Struthers AD (1994) QT dispersion and sudden unexpected death in chronic heart failure. Lancet 343 : 327 329.
6. Berger RD, Kasper EK, Baughman KL, Marban E, Calkins H, Tomaselli GF (1997) Beat-to-beat QT interval variability: novel evidence for repolarization lability in ischemic and nonischemic dilated cardiomyopathy. Circulation 96 : 1557 1565.
7. Buja G, Miorelli M, Turrini P, Melacini P, Nava A (1993) Comparison of QT dispersion in hypertrophic cardiomyopathy between patients with and without ventricular arrhythmias and sudden death. Am J Cardiol 72 : 973 976.
8. Cuculi F, Kobza R, Ehmann T, Erne P (2006) ECG changes amongst patients with alcohol withdrawal seizures and delirium tremens. Swiss Med Wkly 136 : 223 227.
9. Darbar D, Luck J, Davidson N, Pringle T, Main G, McNeill G, Struthers AD (1996) Sensitivity and specificity of QTc dispersion for identification of risk of cardiac death in patients with peripheral vascular disease. BMJ 312 : 874 878. (Pubitemid 126443429)
10. Davey PP, Bateman J, Mulligan IP, Forfar C, Barlow C, Hart G (1994) QT-interval dispersion in chronic heart failure and left ventricular hypertrophy: relation to autonomic nervous system and Holter tape abnormalities. Br Heart J 71 : 268 273.
11. Dean JW, Lab MJ (1989) Arrhythmia in heart failure. Role of mechanically induced changes in electrophysiology. Lancet ii : 1309 1312.
12. Desai N, Raghunandan DS, Mallavarapu M, Berger RD, Yeragani VK (2004) Beat-to-beat heart rate and QT variability in patients with congestive cardiac failure: blunted response to orthostatic challenge. Ann Noninvasive Electrocardiol 9 : 323 329.
13. El-Mas MM, Abdel-Rahman AA (2005) Autonomic modulation of altered diurnal hemodynamic profiles in ethanol-fed hypertensive rats. Alcohol Clin Exp Res 29 : 499 508.
14. Fu GS, Meissner A, Simon R (1997) Repolarization dispersion and sudden cardiac death in patients with impaired left ventricular function. Eur Heart J 18 : 281 289.
15. Galinier M, Balanescu S, Fourcade J, Dorobantu M, Albenque JP, Massabuau P, Doazan JP, Fauvel JM, Bounhoure JP (1997) Prognostic value of arrhythmogenic markers in systemic hypertension. Eur Heart J 18 : 1484 1491. (Pubitemid 27389044)
16. Grassi G, Cattaneo BM, Seravalle G, Lanfranchi A, Pozzi M, Morganti A, Carugo S, Mancia G (1997) Effects of chronic ACE inhibition on sympathetic nerve traffic and baroreflex control of circulation in heart failure. Circulation 96 : 1173 1179.
17. Guideri G, Gutstein WH, Olivetti G, Anversa P (1988) Effects of alcohol on isoproterenol-induced ventricular fibrillation in adult rats. J Cardiovasc Pharmacol 12 : 479 485.
18. Haigney MC, Zareba W, Gentlesk PJ, Goldstein RE, Illovsky M, McNitt S, Andrews ML, Moss AJ (2004) Multicenter Automatic Defibrillator Implantation Trial II investigators. QT interval variability and spontaneous ventricular tachycardia or fibrillation in the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II patients. J Am Coll Cardiol 44 : 1481 1487.
19. Han J, Moe GK (1964) Nonuniform recovery of excitability in ventricular muscle. Circ Res 14 : 44 60.
20. Higham PD, Furniss SS, Campbell RW (1995) QT dispersion and components of the QT interval in ischaemia and infarction. Br Heart J 73 : 32 36.
21. Kaye DM, Lefkovits J, Jennings GL, Bergin P, Broughton A, Esler MD (1995) Adverse consequences of high sympathetic nervous activity in the failing human heart. J Am Coll Cardiol 26 : 1257 1263.
22. Kuo CS, Munakata K, Reddy CP, Surawicz B (1983) Characteristics and possible mechanisms of ventricular arrhythmia dependent on the dispersion of action potential duration. Circulation 67 : 1356 1367.
23. Kupari M, Koskinen P (1998) Alcohol, cardiac arrhythmias and sudden death. Novartis Found Symp 216 : 68 79.
24. Lieber CS, DeCarli LM (1989) Liquid diet technique of ethanol administration: 1989 update. Alcohol Alcohol 24 : 197 211.
25. Liu J, Fujimiya T (2008) Abrupt termination of an ethanol regimen provokes ventricular arrhythmia and enhances susceptibility to the arrhythmogenic effects of epinephrine in rats. Alcohol Clin Exp Res 33 : S1 S9.
26. Liu J, Shirafuji S, Fujimiya T (2009) Rats in acute withdrawal from ethanol exhibit left ventricular systolic dysfunction and cardiac sympathovagal balance shift. Alcohol 43 : 207 216.
27. Liu J, Yano M, Shimamoto A, Noma T, Matsuzaki M, Fujimiya T (2007) Chronic effects of ethanol on pharmacokinetics and left ventricular systolic function in rats. Alcohol Clin Exp Res 31 : 493 499.
28. Malliani A (2005) Heart rate variability, from bench to bedside. Eur J Intern Med 16 : 12 20.
29. Mancia G, Giannattasio C, Grassi G, Morganti A, Zanchetti A (1988) Reflex control of circulation and angiotensin converting enzyme inhibition in man. J Hypertens Suppl 6 : S45 S49.
30. Meredith IT, Broughton A, Jennings GL, Esler MD (1991) Evidence of a selective increase in cardiac sympathetic activity in patients with sustained ventricular arrhythmias. N Engl J Med 325 : 618 624.
31. Ozdemir O, Alyan O, Soylu M, Metin F, Kacmaz F, Demir AD, Geyik B, Aras D, Sasmaz H, Korkmaz S (2005) Improvement in sympatho-vagal imbalance and heart rate variability in patients with mitral stenosis after percutaneous balloon commissurotomy. Europace 7 : 204 210.
32. Pereira-Junior PP, Chaves EA, Costa-E-Sousa RH, Masuda M, de Carvalho AC, Nascimento JH (2006) Cardiac autonomic dysfunction in rats chronically treated with anabolic steroid. Eur J Appl Physiol 96 : 487 494.
33. Periomaki JS, Koisitinen MJ, Yli-Mayry S, Huikuri HV (1995) Dispersion of QT interval in patients with and without susceptibility to ventricular tachyarrhythmias after previous myocardial infarction. J Am Coll Cardiol 26 : 174 179.
34. Piccirillo G, Magnanti M, Matera S, Di Carlo S, De Laurentis T, Torrini A, Marchitto N, Ricci R, Magri D (2006) Age and QT variability index during free breathing, controlled breathing and tilt in patients with chronic heart failure and healthy control subjects. Transl Res 148 : 72 78.
35. Priori SG, Napolitano C, Diehl L, Schwartz PJ (1994) Dispersion of the QT-interval - a marker of therapeutic efficacy in the idiopathic long QT-syndrome. Circulation 89 : 1681 1689.
36. Pye MP, Cobbe SM (1992) Mechanisms of ventricular arrhythmia in cardiac failure and hypertrophy. Cardiovasc Res 26 : 740 750.
37. Starmer CF (1997) The cardiac vulnerable period and reentrant arrhythmias: targets of anti- and proarrhythmic processes. Pacing Clin Electrophysiol 20 : 445 454.
38. Vasallo JA, Cassidy DM, Kindwall KE, Marchlinski FE, Josephson ME (1988) Nonuniform recovery of excitability in the left ventricle. Circulation 78 : 1365 1372.
39. Weiss R, Ferry D, Pickering E, Smith LK, Dennish G III., Krug-Gourley S, Lukas MA (1998) Effectiveness of three different doses of carvedilol for exertional angina. Am J Cardiol 82 : 927 931.
40. Zabel M, Portnoy S, Franz MR (1995) Electrocardiographic indexes of dispersion of ventricular repolarization: an isolated heart validation study. J Am Coll Cardiol 25 : 746 752.