Structural analysis of lipocalin-type prostaglandin D synthase complexed with biliverdin by small-angle X-ray scattering and multi-dimensional NMR

Journal of Structural Biology

Volumn 169, Issue 2, 2010, Pages 209-218

  Miyamoto, Yuya ^a   Nishimura, Shigenori ^a   Inoue, Katsuaki ^b   Shimamoto, Shigeru ^c   Yoshida, Takuya ^c   Fukuhara, Ayano ^a   Yamada, Mao ^a   Urade, Yoshihiro ^d   Yagi, Naoto ^b   Ohkubo, Tadayasu ^c   Inui, Takashi ^a  

^a Osaka Prefecture University   (Japan)

^b JAPAN SYNCHROTRON RADIATION RESEARCH INSTITUTE   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d OSAKA BIOSCIENCE INSTITUTE   (Japan)

Author keywords

Conformational change; Ligand binding; NMR; SAXS; Structural flexibility

Indexed keywords

BILIRUBIN; BILIVERDIN; LIGAND; LIPOCALIN TYPE PROSTAGLANDIN D SYNTHASE; PROSTAGLANDIN D SYNTHASE; RETINOID; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME STRUCTURE; HETERONUCLEAR SINGLE QUANTUM COHERENCE; IN VITRO STUDY; LIGAND BINDING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

ANIMALS; BILIVERDINE; FLUORESCENCE; INTRAMOLECULAR OXIDOREDUCTASES; LIPOCALINS; MICE; MODELS, CHEMICAL; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; SCATTERING, SMALL ANGLE; X-RAY DIFFRACTION;

EID: 74449090243     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2009.10.005     Document Type: Article

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