Oxidation of bilirubin produces compounds that cause prolonged vasospasm of rat cerebral vessels: A contributor to subarachnoid hemorrhage-induced vasospasm

Journal of Cerebral Blood Flow and Metabolism

Volumn 22, Issue 4, 2002, Pages 472-478

  Clark, Joseph F ^a   Reilly, Melinda ^a   Sharp, Frank R ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Bilirubin; Cerebral vasospasm; Hemorrhage; Oxidative stress; Relaxation; Vessel diameter

Indexed keywords

BILIRUBIN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 25; HEAT SHOCK PROTEIN 32; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; BLOOD VESSEL DIAMETER; BRAIN BLOOD VESSEL; BRAIN INJURY; BRAIN VASOSPASM; CEREBROSPINAL FLUID; CONTROLLED STUDY; DOSE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SUBARACHNOID HEMORRHAGE; VASOCONSTRICTION; VASODILATATION;

EID: 0036208465     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-200204000-00011     Document Type: Article

References (42)

1. Effects of okadaic acid on isometric tension and myosin phosphorylation of chemically skinned guinea-pig taenia coli
2. Subarachnoid hemorrhage induced cerebral vasospasm: A subcellular perspective on the control of tension
3. The stimulation of vascular smooth muscle oxidative metabolism by CSF from subarachnoid hemorrhage patients increases with Fisher and WFNS grades
4. Cerebral vasospasm after subarachnoid hemorrhage
5. In vitro therapy with dobutamine, isoprenaline and sodium nitroprusside protects vascular smooth muscle metabolism from subarachnoid hemorrhage induced cerebral vasospasm
6. The effect and management of delayed vasospasm after aneurysmal subarachnoid hemorrhage
7. Bilirubin and the induction of intracranial arterial spasm
8. Causes of morbidity and mortality following intracranial aneurysm rupture
9. Current concepts of pathophysiology and management of cerebral vasospasm following aneurysmal subarachnoid hemorrhage
10. Cerebral vasospasm after subarachnoid hemorrhage: An update
11. Calyculin A and okadaic acid; inhibitors of protein phosphatase activity
12. Randomized, double-blind, vehicle-controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: A cooperative study in Europe, Australia, and New Zealand
13. Vasodilatory effects of okadaic acid on the canine cerebral artery
14. Oxidative degradation of bilirubin produces vasoactive compounds
15. A review of hemoglobin and the pathogenesis of cerebral vasospasm
16. Cerebral vasospasm and free radicals
17. Etiology of cerebral vasospasm in primates
18. Heme-oxygenase-I induction in glia throughout rat brain following experimental subarachnoid hemorrhage
19. Focal hyperexpression of hemeoxygenase-1 protein and messenger RNA in rat brain caused by cellular stress following subarachnoid injections of lysed blood
20. Cerebral vasospasm
21. Cyclic AMP relaxes swine arterial smooth muscle predominantly by decreasing cell Ca2+ concentration
22. Cerebral arterial spasm. Part II: Etiology and treatment of experimental cerebral vasospasm
23. Distribution of angiographic vasospasm after subarachnoid hemorrhage: Implications for diagnosis by transcranial Doppler ultrasonography
24. Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid hemorrhage: British aneurysm nimodipine trial
25. Increased cerebral blood flow but no reversal or prevention of vasospasm in response to L-arginine infusion after subarachnoid hemorrhage
26. The presence of an extractable substance in the CSF of humans with cerebral vasospasm after subarachnoid hemorrhage that correlates with phosphatase inhibition
27. Cerebrospinal fluid from subarachnoid hemorrhage patients causes excessive oxidative metabolism compared to vascular smooth muscle force generation
28. Magnesium protection against in vitro cerebral vasospasm after subarachnoid hemorrhage
29. Phosphatase inhibition with okadaic acid does not alter the relationship between force and myosin light chain phosphorylation in permeabilized smooth muscle
30. Bilirubin is an antioxidant of possible physiological importance
31. Okadaic acid. Protein phosphatase inhibition and muscle contractile effects
32. Smooth muscle myosin phosphatase inhibition and force enhancement by black sponge toxin
33. Reversal of severe cerebral vasospasm in three patients after aneurysmal subarachnoid hemorrhage: Initial observations regarding the use of intraventricular sodium nitroprusside in humans
34. Bilirubin levels in subarachnoid clot and effects on canine arterial smooth muscle cells
35. Heme oxygenase-1 is induced in glia throughout brain by subarachnoid hemoglobin
36. Anti-oxidants prevent focal rat brain injury as assessed by induction of heat shock proteins (HSP70, HO-1/HSP32, HSP47) following subarachnoid injections of lysed blood
37. The pathophysiology of cerebral vasospasm
38. Etiology of cerebral vasospasm
39. Reversal of cerebral vasospasm using an intrathecally administered nitric oxide donor
40. Excitation-contraction coupling and relaxation in porcine carotid arteries are specifically dependent on glucose
41. Mechanisms of [Ca++]i elevation induced by erythrocyte components in endothelial cells
42. Mechanism of endothelin-1-induced contraction in rabbit basilar artery