Effect of delivery of MMP inhibitors from PDMS as a model IOL material on PCO markers

Biomaterials

Volumn 31, Issue 8, 2010, Pages 2399-2407

  Morarescu, Diana ^a   West Mays, Judy A ^a   Sheardown, Heather D ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Controlled drug release; Lens epithelial cells; Matrix metalloproteinase inhibitor; Migration; Polydimethylsiloxane; Posterior capsule opacification

Indexed keywords

CONTROLLED DRUG RELEASE; LENS EPITHELIAL CELLS; MATRIX METALLOPROTEINASE INHIBITOR; MATRIX METALLOPROTEINASES; POSTERIOR CAPSULE OPACIFICATION;

BLOOD VESSELS; CELLS; CONTACT LENSES; ENZYME INHIBITION; OPTICAL INSTRUMENTS; SILICONES; ULSI CIRCUITS;

INTRAOCULAR LENSES;

DIMETICONE; ILOMASTAT; MATRIX METALLOPROTEINASE 2 INHIBITOR I; MATRIX METALLOPROTEINASE 9 INHIBITOR II; MATRIX METALLOPROTEINASE INHIBITOR; NANOMATERIAL; UNCLASSIFIED DRUG;

ARTICLE; CATARACT; CELL MIGRATION; CONTROLLED STUDY; DISEASE MARKER; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; DRUG STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; LENS EPITHELIUM; LENS IMPLANT; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIOLOGICAL MARKERS; CATARACT; CELLS, CULTURED; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENZYME INHIBITORS; EPITHELIAL CELLS; HUMANS; ISOENZYMES; LENS CAPSULE, CRYSTALLINE; LENSES, INTRAOCULAR; MATERIALS TESTING; MATRIX METALLOPROTEINASES; MOLECULAR STRUCTURE; RETINAL PIGMENT EPITHELIUM; SILICONE ELASTOMERS;

EID: 74449085136     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.11.108     Document Type: Article

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