A systematic review of the association between the Behavioral and Psychological Symptoms of Dementia and burden of care

International Psychogeriatrics

Volumn 16, Issue 3, 2004, Pages 295-315

  Black, Warwick ^a   Almeida, Osvaldo P ^b  

^a Perth Radiological Clinic   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Aggression; Alzheimer's disease; Anxiety; Behavioural and psychological symptoms; Burden; Caregiver; Carer; Delusion; Dementia; Depression; Hallucination; Irritability; Psychosis; Residential care; Stress; Systematic review

Indexed keywords

BEHAVIOR DISORDER; CAREGIVER; CLINICAL RESEARCH; CORRELATION COEFFICIENT; DEMENTIA; DEPRESSION; DISTRESS SYNDROME; HUMAN; MEDICAL INFORMATION; MEDICAL RECORD; MEDLINE; MENTAL DISEASE; MULTIVARIATE ANALYSIS; RATING SCALE; REVIEW; SYSTEMATIC REVIEW;

AGED; CROSS-SECTIONAL STUDIES; DEMENTIA; HUMANS; LONGITUDINAL STUDIES; MENTAL DISORDERS; MIDDLE AGED;

EID: 7444270285     PISSN: 10416102     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1041610204000468     Document Type: Review

References (78)

1. Australian Bureau of Statistics (1999a). Australian Social Trends 1999. Population - Population Projections: our ageing population. http://www.abs.gov. au/ausstats/abs@.nsf/0/B7760619C3973594CA25699F0005D60F?Open [Accessed online 7 July 2003].
2. Australian Bureau of Statistics (1999b). Australian Social Trends 1999: Housing - Housing assistance: home care, hostels and nursing homes. http://www.abs.gov.au/ausstats/abs@.nsf/0/0A47979AD5E28B11CA25699F0005D636?Open [Accessed online 7 July 2003].
3. Alspaugh, M. E. L., Stephens, M. A. P., Kinney, J. M., Ogrocki, P. K. and Townsend, A. L. (1999). Longitudinal patterns of risk for depression in dementia caregivers: objective and subjective primary stress as predictors. Psychology and Aging, 14, 34-43.
4. Altman, D. G. (1991). Practical Statistics for Medical Research. London: Chapman and Hall.
5. American Psychiatric Association (1987). Diagnostic and Statistical Manual of Mental Disorders (3rd ed., revised). Washington, DC: American Psychiatric Association.
6. American Psychiatric Association (1994). Diagnosis and Statistical Manual of Mental Disorders (4th ed.). Washington, DC: American Psychiatric Association.
7. Asada, T., Kinoshita, T. and Kakuma, T. (2000). Analysis of behavioral disturbances among community-dwelling elderly with Alzheimer Disease. Alzheimer Disease and Associated Disorders, 14, 160-167.
8. Bachman, D. L., Wolfe, P. A., Linn, R., Knoefel, J. E., Cobb, J. L. and Belanger, A. J. (1993). Incidence of dementia and probable dementia of Alzheimer type in the Framingham study. Neurology, 42, 115-119.
9. Ballard, C. G., Saad, K., Coope, B., Graham, C., Gahir, M., Wilcock, G. K. and Oyebode, F. (1995). The aetiology of depression in the carers of dementia sufferers. Journal of Affective Disorders, 35, 59-63.
10. Ballard, C. G., Eastwood, C., Gahir, M. and Wilcock, G. K. (1996). A follow-up study of depression in the carers of dementia sufferers. British Medical Journal, 312, 947.
11. Ballard, C., Lowery, K., Powell, I., O'Brien, J. and James, I. (2000). Impact of Behavioral and Psychological Symptoms of Dementia on caregivers. International Psychogeriatrics, 12, Suppl 1, 93-105.
12. Baumgarten, M., Battista, R. N., Infante-Rivard, C., Hanley, J. A., Becker, R. and Gauthier, S. (1992). The psychological and physical health of family members caring for an elderly person with dementia. Journal of Clinical Epidemiology, 45, 61-70.
13. Bedard, M., Molloy, D. W., Pedlar, D., Lever, J. A. and Stones, M. J. (1997). Associations between dysfunctional behaviors, gender, and burden in spousal caregivers of cognitively impaired older adults. International Psychogeriatrics, 9, 277-290.
14. Bedard, M., Pedlar, D., Martin, N. J., Malott, O. and Stones, M. J. (2000). Burden in caregivers of cognitively impaired older adults living in the community: methodological issues and determinants. International Psychogeriatrics, 12, 307-332.
15. Bedard, M., Raney, D., Molloy, D. W., Lever, J., Pedlar, D. and Dubois, S. (2001). The experience of primary and secondary caregivers caring for the same adult with Alzheimer's disease. Journal of Mental Health and Aging, 7, 287-296.
16. Boothby, H., Blizard, R., Livingston, G. and Mann, A. H. (1994). The Gospel Oak Study Stage III: the incidence of dementia. Psychological Medicine, 24, 89-95.
17. Braekhus, A., Oskengard, A. R., Engedal, K. and Laake, K. (1998). Social and depressive stress suffered by spouses of patients with mild dementia. Scandinavian Journal of Primary Health Care, 16, 242-246.
18. Brodaty, H. (1996). Caregivers and behavioral disturbances: effects and interventions. International Psychogeriatrics, 8, 455-458.
19. Brodaty, H. and Luscombe, G. (1998). Psychological morbidity in caregivers is associated with depression in patients with dementia. Alzheimer's Disease and Associated Disorders, 12, 62-70.
20. Burns, A. (2000). Behavioral and psychological symptoms of dementia and caregiver burden. International Psychogeriatrics, 12, 347-350.
21. Caron, W. C., Boss, P. and Mortimer, J. (1999). Family boundary ambiguity predicts Alzheimer's outcomes. Psychiatry, 62, 347-355.
22. Chappell, N. L. and Penning, M. (1996). Behavioral problems and distress among caregivers of people with dementia. Ageing and Society, 16, 57-73.
23. Claus, J. J., Teunisse, S., Walstra, G. J. and van Gool, W. A. (1998). Determinants of global clinical change assessment in patients with early Alzheimer's disease. Dementia and Geriatric Cognitive Disorders, 9, 157-163.
24. Coen, R. F., O'Boyle, C. A., Swanwick, G. R. J. and Coakley, D. (1999). Measuring the impact on relatives of caring for people with Alzheimer's disease: quality of life, burden and well-being. Psychology and Health, 14, 253-261.
25. Commission of the European Communities (2002). Communication from the Commission to the Council and the European Parliament; Europe's response to World Ageing. Brussels: Commission of the European Communities.
26. Cummings, J. L. (1996). Neuropsychiatric assessment and intervention in Alzheimer's Disease. International Psychogeriatrics, 8, 25-30.
27. Derogatis, L. R., Lipman, R. S. and Covi, L. (1973). SCL-90: an outpatient psychiatric rating scale. Preliminary report. Psychopharmacology Bulletin, 30, 585-594.
28. Donaldson, C., Tarrier, N. and Burns, A. (1997). The impact of the symptoms of dementia on caregivers. British Journal of Psychiatry, 170, 62-68.
29. Donaldson, C., Tarrier, N. and Burns, A. (1998). Determinants of carer stress in Alzheimer's disease. International Journal of Geriatric Psychiatry, 13, 248-256.
30. Dunkin, J. J. and Anderson-Hanley, C. (1998). Dementia caregiver burden: a review of the literature and guidelines for assessment and intervention. Neurology, 51, 53-60.
31. Elmstahl, S., Ingvad, B. and Annerstedt, L. (1998). Family caregiving in dementia: prediction of caregiver burden 12 months after relocation to group-living care. International Psychogeriatrics, 10, 127-146.
32. Finkel, S. L, Coste e Silva, J., Cohen, G., Miller, S. and Sartorius, N. (1996). Behavioral and psychological signs and symptoms of dementia: a consensus statement on current knowledge and implications for research and treatment. International Psychogeriatrics, 8, 497-500.
33. Flicker, L. (1992). The effects of caregiving for the demented elderly. Australian Journal on Ageing, 11, 9-15.
34. Fuh, J.-L., Wang, S.-J., Liu, C.-Y. and Wang, H.-C. (1999a). Predictors of depression among Chinese family of caregivers of Alzheimer patients. Alzheimer Disease and Associated Disorders, 13, 171-175.
35. Fuh, J.-L., Wang, S.-J., Liu, H.-C. and Wang, H.-C. (1999b). The caregiving burden scale among Chinese caregivers of Alzheimer patients. Dementia and Geriatric Cognitive Disorders, 10, 186-191.
36. Gallagher-Thompson, D., Brooks, J. O., Bliwise, D., Leader, J. and Yesavage, J. A. (1992). The relations among caregiver stress, "sundowning" symptoms, and cognitive decline in Alzheimer's disease. Journal of the American Geriatrics Society, 40, 807-810.
37. Gaugler, J. E., Pearlin, L. I., Davey, A. and Zarit, S. H. (2000). Modelling caregiver adaptation over time: the longitudinal impact of behavior problems. Psychology and Aging, 15, 437-450.
38. Gaugler, J. E., Pearlin, L. I., Leitsch, S. A. and Davey, A. (2001). Relinquishing in-home dementia care: difficulties and perceived helplessness during the nursing home transition. American Journal of Alzheimer's Disease and Other Dementias, 16, 32-42.
39. Gonzalez-Salvador, M. T., Arango, C., Lyketsos, C. G. and Barba, A. C. (1999). The stress and psychological morbidity of the Alzheimer patient caregiver. International Journal of Geriatric Psychiatry, 14, 701-710.
40. Goode, K. T., Haley, W. E., Roth, D. L. and Ford, G. R. (1998). Predicting longitudinal changes in caregiver physical and mental health: a stress process model. Health Psychology, 17, 190-198.
41. Grafstrom, M. and Winblad, B. (1995). Family burden in the care of the demented and non-demented elderly - a longitudinal study. Alzheimer Disease and Associated Disorders, 9, 78-86.
42. Graham, C., Ballard, C. and Sham, P. (1997). Carers' knowledge of dementia, their coping strategies and morbidity. International Journal of Geriatric Psychiatry, 12, 931-936.
43. Greene, J. G., Smith, R., Gardiner, M. and Timbury, G. C. (1982). Measuring behavioral disturbance of elderly demented patients in the community and its effect on relatives. Age and Ageing, 11, 121-126.
44. Harwood, D. G., Barker, W. W., Cantillon, M., Loewenstein, D. A., Ownby, R. and Duara, R. (1998). Depressive symptomatology in first-degree family caregivers of Alzheimer Disease patients: a cross-ethnic comparison. Alzheimer Disease and Associated Disorders, 12, 340-346.
45. Harwood, D. G., Barker, W. W., Ownby, R. L., Bravo, M., Aguero, H. and Duara, R. (2000a). Predictors of positive and negative appraisal among Cuban American caregivers of Alzheimer's patients. International Journal of Geriatric Psychiatry, 15, 481-487.
46. Harwood, D. G., Barker, W. W., Ownby, R. L. and Duara, R. (2000b). Caregiver self-rated health in Alzheimer's disease. Clinical Gerontologist, 21, 19-33.
47. Harwood, D. G., Ownby, R. L., Burnett, K., Barker, W. W. and Duara, R. (2000c). Predictors of appraisal and psychological well-being in Alzheimer's disease family caregivers. Journal of Clinical Geropsychology, 6, 279-297.
48. Harwood, D. G., Barker, W. W., Ownby, R. L., Bravo, M., Aguero, H. and Duara, R. (2001). The Behavior Problems Checklist-Spanish: a preliminary study of a new scale for the assessment of depressive symptoms and disruptive behaviors in Hispanic patients with dementia. International Psychogeriatrics, 13, 23-35.
49. Hebert, R., Dubois, M. F., Wolfson, C., Chambers, L. and Cohen, C. (2001). Factors associated with long-term institutionalization of older people with dementia: data from the Canadian Study of Health and Aging. Journal of Gerontology, 56A, 693-699.
50. Kua Ee Heok and Li, T. S. (1997). Stress of caregivers of dementia patients in the Singapore Chinese family. International Journal of Geriatric Psychiatry, 12, 466-469.
51. LoGuidice, D., Waltrowicz, W., McKenzie, S., Ames, D. and Flicker, L. (1995). Prevalence of dementia among patients referred to an aged care assessment team and associated stress in their carers. Australian Journal of Public Helath, 19, 275-279.
52. LoGiudice, D. C. and Ames, D. J. (1999). Dementia: current and future challenges. Medical Journal of Australia, 171, 228-229.
53. Lowery, K., Mynt, P., Aisbett, J., Dixon, T., O'Brien, J. and Ballard, C. (2000). Depression in the carers of dementia sufferers: a comparison of the carers of patients suffering from dementia with Lewy Bodies and the carers of patients with Alzheimer's Disease. Journal of Affective Disorders, 59, 61-65.
54. Magai, C. and Cohen, C. I. (1998). Attachment style and emotion regulation in dementia patients and their relation to caregiver burden. Journals of Gerontology. Series B, Psychological Sciences and Social Sciences, 53, 147-154.
55. Majerovitz, S.D. (1995). Role of family adaptability in the psychological adjustment of spouse caregivers to patients with dementia. Psychology and Aging, 10, 447-457.
56. Mangone, C. A. et al. (1993). Influence of feelings of burden on the caregiver's perception of the patient's functional status. Dementia, 4, 287-293.
57. McDaid, D. (2001). Estimating the costs of informal care for people with Alzheimer's disease: methodological and practical challenges. International Journal of Geriatric Psychiatry, 16, 400-405.
58. McKeith, I. G. et al. (1996). Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology, 47, 1113-1124.
59. McKhann, G., Drachmann, D., Folstein, M., Katzman, R., Pryce, D. and Stadlan, E. (1984). Clinical diagnosis of Alzheimer's disease: Report of the NINCDS/ADRDA workgroup. Neurology, 34, 939-944.
60. Neundorfer, M. M., McClendon, M. J., Smyth, K. A., Stuckey, J. C., Strauss, M. E. and Patterson, M. B. (2001). A longitudinal study of the relationship between levels of depression among persons with Alzheimer's disease and levels of depression among their family caregivers. Journal of Gerontology Series B - Psychological Sciences and Social Sciences, 56, 301-313.
61. O'Rourke, N. and Tuokko, H. (2000). The psychological and physical costs of caregiving: the Canadian Study of Health and Aging. Journal of Applied Gerontology, 19, 389-404.
62. Philp, I. et al. (1997). Institutionalization risk amongst people with dementia supported by family carers in a Scottish city. Aging and Mental Health, 1, 339-345.
63. Pot, A. M., Deeg, D. J., van Dyck, R. and Jonker, C. (1998). Psychological distress of caregivers: the mediator effect of caregiving appraisal. Patient Education and Counseling, 34, 43-51.
64. Prescop, K. L., Dodge, H. H., Morycz, R. K., Schulz, R. M. and Ganguli, M. (1999). Elders with dementia living in the community with and without caregivers: an epidemiological study. International Psychogeriatrics, 11, 235-250.
65. Reis, M. F., Gold, D. P., Andres, D., Markiewicz, D. and Gauthier, S. (1994). Personality traits as determinants of burden and health complaints in caregiving. International Journal of Aging and Human Development, 39, 257-71.
66. Roman, G. C., Tatemichi, T. K., Erkinjuntii, T. et al. (1994). Vascular dementia: diagnostic criteria for research studies: report of the NINCDS-AIREN International Workshop. Neurology, 43, 250-260.
67. Schulz, R. and Williamson, G. M. (1991). A 2-year longitudinal study of depression among Alzheimer's caregivers. Psychology and Aging, 6, 569-578.
68. Schulz, R., O'Brien, A. T., Bookwala, J. and Fleissner, K. (1995). Psychiatric and physical morbidity effects of dementia caregiving: prevalence, correlates, and causes. The Gerontologist, 35, 771-791.
69. Spruytte, N., Van Audenhove, C. and Lammertyn, F. (2001). Predictors of institutionalization of cognitively-impaired elderly cared for by their relatives. International Journal of Geriatric Psychiatry, 16, 1119-1128.
70. Stuckey, J. C., Neundorfer, M. M. and Smyth, K. A. (1996). Burden and well-being: the same coin or related currency? The Gerontologist, 36, 686-693.
71. Teri, L., Truax, P., Logsdon, R., Uomoto, J., Zarit, S. and Vitaliano, P. P. (1992). Assessment of behavioral problems in dementia: the Revised Memory and Behavior Problems Checklist. Psychology and Aging, 7, 627-631.
72. Teri, L. (1997). Behavior and caregiver burden: behavioral problems in patients with Alzheimer Disease and its association with caregiver distress. Alzheimer Disease and Associated Disorders, 11, S35-S38.
73. United Nations (2001). Bulletin on Ageing No 2, 2000. Division for Social Policy and Development. New York: United Nations Secretariat.
74. Victoroff, J., Mack, W. J. and Nielson, K. A. (1998). Psychiatric complications of dementia: impact on caregivers. Dementia and Geriatric Cognitive Disorders, 9, 50-55.
75. Vitaliano, P. P., Young, H. M. and Russo, J. (1991). Burden: a review of measures used among caregivers of individuals with dementia. The Gerontologist, 31, 67-75.
76. World Health Organisation (1993). ICD-10 Classification of Mental and Behavioural Disorders: Diagnostic Criteria for Research. Geneva: WHO.
77. Zanetti, O., Eugenio, M., Sandri, C. and Frisoni, G.B. (1996). Determinants of burden in an Italian sample of Alzheimer's patient caregivers. Journal of Cross-Cultural Gerontology, 11, 17-27.
78. Zarit, S. H. (1996). Behavioral disturbances of dementia and caregiver issues. International Psychogeriatrics, 8, 263-268.