Requirement of different mitochondrial targeting sequences of the yeast mitochondrial transcription factor Mtf1p when synthesized in alternative translation systems

Biochemical Journal

Volumn 383, Issue 2, 2004, Pages 383-391

  Biswas, Tapan K ^a   Getz, Godfrey S ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Mitochondria; Protein import; Saccharomyces cerevisiae; Transcription factor

Indexed keywords

LOW TEMPERATURE EFFECTS; MEMBRANES;

IN VITRO; MITOCHONDRIAL (MT) TRANSLOCATIONS; MUTANTS; TRANSCRIPTION FACTORS;

BIOCHEMICAL ENGINEERING;

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MTF1P; UNCLASSIFIED DRUG;

ARTICLE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RETICULOCYTE LYSATE; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION;

ANIMALS; CATIONS; CELL-FREE SYSTEM; CHELATING AGENTS; DOXORUBICIN; MEMBRANE POTENTIALS; METALS; MITOCHONDRIA; PHOSPHOLIPIDS; PLANT EXTRACTS; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; RABBITS; REDUCING AGENTS; RETICULOCYTES; RIBONUCLEASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION; SULFHYDRYL COMPOUNDS; TEMPERATURE; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC; TRITICUM; TRYPSIN;

ORYCTOLAGUS CUNICULUS; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; TRITICUM AESTIVUM;

EID: 7444250660     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20040691     Document Type: Article

References (59)

1. Tzagoloff, A. and Myers, A. M. (1986) Genetics of mitochondrial biogenesis. Annu. Rev. Biochem. 55, 249-285
2. Attardi, G. and Schatz, G. (1988) Biogenesis of mitochondria. Annu. Rev. Cell Biol. 4, 289-333
3. Costanzo, M. C. and Fox, T. D. (1990) Control of mitochondrial gene expression in Saccharomyces cerevisiae. Annu. Rev. Genet. 24, 91-113
4. Grivell, L. A. (1995) Nucleo-mitochondrial interactions in mitochondrial gene expression. Critical Rev. Biochem. Mol. Biol. 30, 121-164
5. Verner, K. (1993) Co-translational protein import into mitochondria: an alternative view. Trends Biochem. Sci. 18, 366-371
6. Neupert, W. (1997) Protein import into mitochondria. Annu. Rev. Biochem. 66, 863-917
7. Lithgow, T. (2000) Targeting of proteins to mitochondria. FEBS Lett. 476, 22-26
8. Planner, N. and Chacinska, A. (2002) The mitochondrial import machinery: preprotein-conducting channels with binding sites for presequences. Biochim. Biophys. Acta 1592, 15-24
9. Schatz, G. and Dobberstein, B. (1996) Common principles of protein translocation across membranes. Science 271, 1519-1526
10. Weinhues, U., Becker, K., Schleyer, M., Gulard, B., Tropschug, M., Norwich, A. L., Planner, N. and Neupert, W. (1991) Protein folding causes an arrest of preprotein translocation into mitochondria in vivo. J. Cell Biol. 115, 1601-1609
11. Eilers, M., Hwang, S. and Schatz, G. (1988) Unfolding and refolding of a purified precursor protein during import into isolated mitochondria. EMBO J. 7, 1139-1145
12. Matouscheck, A., Pfanner, N. and Voos, W. (2000) Protein unfolding by mitochondria. The Hsp70 import motor. EMBO Rep. 1, 404-410
13. Mattingly, Jr, J. R., Youself, J., Iriarte, A. and Martinez-Carrion, M. (1993) Protein folding in a cell-free translation system. The late of the precursor to mitochondrial aspartate amino transferase. J. Biol. Chem. 268, 3925-3937
14. Wachter, C., Schatz, G. and Click, B. S. (1994) Protein import into mitochondria: the requirement for external ATP is precursor-specific whereas intramitochondrial ATP is universally needed for translocation into the matrix. Mol. Biol. Cell 5, 465-474
15. Adrian, G. S., McGammon, M. T., Montgomery, D. L. and Douglas, M. G. (1986) Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial inner membrane. Mol. Cell. Biol. 6, 626-634
16. Diekert, K., Kispal, G., Guiard, B. and Lill, R. (1999) An internal targeting signal directing proteins into the mitochondrial intermembrane space. Proc. Natl. Acad. Sci. U.S.A. 96, 11752-11757
17. Folsch, H., Guiard, B., Neupert, W. and Stuart, R. A. (1996) Internal targeting signal of the BCS1 protein: a novel mechanism of import into mitochondria. EMBO J. 15, 479-487
18. Nguyen, M., Millar, D. G., Yong, V. W., Korsmeyer, S. J. and Shore, G. C. (1993) Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence. J. Biol. Chem. 268, 25265-25268
19. Nye, S. H. and Scarpulla, R. C. (1990) Mitochondrial targeting of yeast apoiso-1-cytochrome c is mediated through functionally independent structural domains. Mol. Cell. Biol. 10, 5763-5771
20. Rodriguez-Cousino, N., Nargang, F. E., Baardman, R., Neupert, W., Lill, R. and Court, D. A. (1998) An import signal in the cytosolic domain of the Neurospora mitochondrial outer membrane protein TOM22. J. Biol. Chem. 273, 11527-11532
21. Jang, S. H. and Jaehning, J. A. (1991) The yeast mitochondrial RNA polymerase specificity factor, MTF1, is similar to bacterial sigma factors. J. Biol. Chem. 266, 22671-22677
22. Sanyal, A. and Getz, G. S. (1995) Import of transcription factor MTF1 into the yeast mitochondria takes place through an unusual pathway. J. Biol. Chem. 270, 11970-11976
23. Biswas, T. K. and Getz, G. S. (2002) Import of yeast mitochondrial transcription factor (Mtf1p) via a nonconventional pathway. J. Biol. Chem. 277, 45704-45714
24. Daum, G., Bohni, P. C. and Schatz, G. (1982) Import of proteins into mitochondria cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria. J. Biol. Chem. 257, 13028-13033
25. Chirico, W. J., Waters, M. G. and Blobel, G. (1988) 70K heat shock related proteins stimulate protein translocation into microsomes. Nature (London) 332, 805-810
26. Fecycz, I. T. and Blobel, G. (1987) Soluble factors stimulating secretory protein translocation in bacteria and yeast can substitute for each other. Proc. Natl. Acad. Sci. U.S.A. 84, 3723-3727
27. Hakvoort, T. B., Sprinkle, J. R. and Margoliash, E. (1990) Reversible import of apocytochrome c into mitochondria. Proc. Natl. Acad. Sci. U.S.A. 87, 4996-5000
28. Murakami, H., Pain, D. and Blobel, G. (1988) 70-kD heat shock-related protein is one of at least two distinct cytosolic factors stimulating protein import into mitochondria. J. Cell Biol. 107, 2051-2057
29. Murakami, K. and Mori, M. (1990) Purified presequence binding factor (PBF) forms an import-competent complex with a purified mitochondrial precursor protein. EMBO J. 9, 3201-3208
30. Horst, M., Azem, A., Schatz, G. and Click, B. S. (1997) What is the driving force for protein import into mitochondria? Biochim. Biophys. Acta 1318, 71-78
31. Waters, M. G., Chirico, W. J. and Blobel, G. (1986) Protein translocation across the yeast microsomal membrane is stimulated by a soluble factor. J. Cell Biol. 103, 2629-2636
32. Walter, P., Gilmore, R. and Globel, G. (1984) Protein translocation across the endoplasmic reticulum. Cell (Cambridge, Mass.) 38, 5-8
33. Rassow, J., Guiard, B., Wienhues, U., Herzog, V., Hartl, F.-U. and Neupert, W. (1989) Translocation arrest by reversible folding of a precursor protein imported into mitochondria. A means to quantitate translocation contact sites. J. Cell Biol. 109, 1421-1428
34. Planner, N. and Neupert, W. (1987) Distinct steps in the import of ADP/ATP carrier into mitochondria. J. Biol. Chem. 262, 7528-7536
35. Keibler, M., Keil, P., Schneider, H., van der Klei, I. J., Pfanner, N. and Neupert, W. (1993) The mitochondrial receptor complex: a central role of MOM22 in mediating preprotein transfer from receptors to the general insertion pore. Cell (Cambridge, Mass.) 74, 483-492
36. Sollner, T., Pfaller, R., Griffiths, G., Planner, N. and Neupert, W. (1990) A mitochondrial import receptor for the ADP/ATP carrier. Cell (Cambridge, Mass.) 62, 107-115
37. Pilon, M., Jordi, W., de Kruijiff, B. and Demel, R. A. (1987) Interactions of mitochondrial precursor protein apocytochrome c with phosphatidylserine in model membranes. A monolayer study. Biochim. Biophys. Acta 902, 207-216
38. Getz, G. S., Bartley, W., Stirpe, F., Notion, B. M. and Renshaw, A. (1962) The lipid composition of rat liver mitochondria, fluffy layer and microsomes. Biochem. J. 83, 181-191
39. Hajek, P. and Bedwell, D. M. (1994) Characterization of the mitochondrial binding and import properties of purified yeast F1-ATPase beta subunit precursor. Import requires external ATP J. Biol. Chem. 269, 7192-7200
40. Endo, T., Eilers, M. and Schatz, G. (1989) Binding of a tightly folded artificial mitochondrial precursor protein to the mitochondrial outer membrane involves a lipid-mediated conformational change. J. Biol. Chem. 264, 2951-2956
41. Pilon, M., de Kruijiff, B. and Weisbeek, P. J. (1992) New insights into the import mechanism of the ferredoxin precursor into chloroplasts. J. Biol. Chem. 267, 2548-2556
42. von Stedingk, E. M., Pavlov, P. R, Grinkevich, V. A. and Glaser, E. (1997) Mitochondrial protein import: modification of sulfhydryl groups of the inner mitochondrial membrane import machinery in Solanum tuberosum inhibits protein import. Plant Mol. Biol. 35, 809-820
43. Hachiya, N., Alam, R., Sakasegawa, Y., Sakaguchi, M., Mihara, K. and Omura, T. (1993) A mitochondrial import factor purified from rat liver cytosol is an ATP-dependent informational modulator for precursor proteins. EMBO J. 12, 1579-1586
44. Seedorf, M. and Soll, J. (1995) Copper chloride, an inhibitor of protein import into chloroplasts. FEBS Lett. 367, 19-22
45. Voos, W., Martin, H., Krimmer, T. and Planner, N. (1999) Mechanisms of protein translocation into mitochondria. Biochim. Biophys. Acta 1422, 235-254
46. Terada, K. and Mori, M. (2000) Human DnaJ homologs dj2 and dj3, and bag-1 are positive cochaperones of hsc70. J. Biol. Chem. 275, 24728-24734
47. Hurt, E. C., Muller, U. and Schatz, G. (1985) The first twelve amino acids of a yeast mitochondrial outer membrane protein can direct a nuclear-coded cytochrome oxidase subunit to the mitochondrial inner membrane. EMBO J. 4, 3509-3518
48. Arakawa, H., Takiguchi, M., Amaya, Y., Nagata, S., Hayashi, H. and Mori, M. (1987) cDNA-derived amino acid sequence of rat mitochondrial 3-oxoacyl-CoA thiolase with no transient presequence: structural relationship with peroxisomal isozyme. EMBO J. 6, 1361-1366
49. Schricker, R., Magdolen, V. and Bandlow, W. (1992) A new member of the adenylate kinase family in yeast: PAK3 is highly homologous to mammalian AK3 and is targeted to mitochondria. Mol. Gen. Genet. 33, 363-371
50. Bandlow, W., Strobel, G. and Schricker, R. (1998) Influence of N-terminal sequence variation on the sorting of major adenylate kinase to the mitochondrial intermembrane space in yeast. Biochem. J. 329, 359-367
51. DeLabre, M. L., Nett, J. H. and Trumpower, B. L. (1999) The cleaved presequence is not required for import of subunit 6 of the cytochrome bc1 complex into yeast mitochondria or assembly into the complex. FEBS Lett. 449, 201-205
52. Zara, V., Palmieri, F., Mahlke, K. and Planner, N. (1992) The cleavable presequence is not essential for import and assembly of the phosphate carrier of mammalian mitochondria but enhances the specificity and efficiency of import. J. Biol. Chem. 267, 12077-12081
53. Muckel, E. and Soil, J. (1996) A protein import receptor of chloroplasts is inserted into the outer envelope membrane by a novel pathway. J. Biol. Chem. 266, 23846-23852
54. Lill, R., Stuart, R. A., Drygas, M. E., Narang, F. E. and Neupert, W. (1992) Import of cytochrome c heme lyase into mitochondria: a novel pathway into the intermembrane space. EMBO J. 11, 449-456
55. Miller, B. R. and Cumsky, M. G. (1991) An unusual mitochondrial import pathway for the precursor to yeast cytochrome c oxidase subunit Va. J. Cell Biol. 112, 833-841
56. Schwarze, S. R., Ho, A., Vocero-Akbani, A. and Dowdy, S. F. (1999) In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285, 1569-1572
57. Derossi, D., Calvet, S., Trembleau, A., Brunissen, A., Chassaing, G. and Prochiantz, A. (1996) Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. J. Biol. Chem. 271, 18188-18193
58. Derossi, D., Chassaing, G. and Prochiantz, A. (1998) Trojan peptides: the penetrating system for intracellular delivery. Trends Cell. Biol. 8, 84-87
59. Kurz, M., Martin, H., Rassow, J., Pfanner, N. and Ryan, M. T. (1999) Biogenesis of Tim proteins of the mitochondrial carrier import pathway: differential targeting mechanisms and crossing over with the main import pathway. Mol. Biol. Cell 10, 2461-2474