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Volumn 33, Issue 1, 2010, Pages 60-72

Soluble recombinant CMVpp65 spanning multiple HLA alleles for reconstitution of antiviral CD4+ and CD8+ T-cell responses after allogeneic stem cell transplantation

Author keywords

Adoptive immunotherapy; Antiviral T cells; CMVpp65; Human cytomegalovirus; Stem cell transplantation

Indexed keywords

CYTOMEGALOVIRUS ANTIGEN PP65; GAMMA INTERFERON; HLA A ANTIGEN; HYBRID PROTEIN; IMMEDIATE EARLY PROTEIN; RECOMBINANT PROTEIN; VIRUS PROTEIN;

EID: 74349110271     PISSN: 15249557     EISSN: None     Source Type: Journal    
DOI: 10.1097/CJI.0b013e3181b56dcc     Document Type: Article
Times cited : (9)

References (43)
  • 2
    • 2542476855 scopus 로고    scopus 로고
    • Clinical aspects of CMV infection after stem cell transplantation
    • Hebart H, Einsele H. Clinical aspects of CMV infection after stem cell transplantation. Hum Immunol. 2004;65: 432-436.
    • (2004) Hum Immunol , vol.65 , pp. 432-436
    • Hebart, H.1    Einsele, H.2
  • 3
    • 40849098721 scopus 로고    scopus 로고
    • + T-cell reconstitution in adult allogeneic hematopoietic stem cell transplant recipients and immune control of viral infection
    • + T-cell reconstitution in adult allogeneic hematopoietic stem cell transplant recipients and immune control of viral infection. Haematologica. 2008;93: 248-256.
    • (2008) Haematologica , vol.93 , pp. 248-256
    • Lilleri, D.1    Fornara, C.2    Chiesa, A.3
  • 4
    • 0034176751 scopus 로고    scopus 로고
    • Increased transplant-related morbidity and mortality in CMV-seroposi-tive patients despite highly effective prevention of CMV disease after allogeneic T-cell-depleted stem cell transplantation
    • Broers AE, van Der Holt R, van Esser JW, et al. Increased transplant-related morbidity and mortality in CMV-seroposi-tive patients despite highly effective prevention of CMV disease after allogeneic T-cell-depleted stem cell transplantation. Blood. 2000;95:2240-2245.
    • (2000) Blood , vol.95 , pp. 2240-2245
    • Broers, A.E.1    Van Der Holt, R.2    Van Esser, J.W.3
  • 5
    • 0028820386 scopus 로고
    • Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor
    • Walter EA, Greenberg PD, Gilbert MJ, et al. Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N Engl J Med. 1995;333:1038-1044.
    • (1995) N Engl J Med , vol.333 , pp. 1038-1044
    • Walter, E.A.1    Greenberg, P.D.2    Gilbert, M.J.3
  • 6
    • 42449123139 scopus 로고    scopus 로고
    • Detailed analysis of cytomegalovirus (CMV)-specific T cells expanded for adoptive immunotherapy of CMV infection following allogeneic stem cell transplantation for malignant disease
    • Hobeika A, Osada T, Serra D, et al. Detailed analysis of cytomegalovirus (CMV)-specific T cells expanded for adoptive immunotherapy of CMV infection following allogeneic stem cell transplantation for malignant disease. Cytotherapy. 2008; 10:289-302.
    • (2008) Cytotherapy , vol.10 , pp. 289-302
    • Hobeika, A.1    Osada, T.2    Serra, D.3
  • 7
    • 0036357480 scopus 로고    scopus 로고
    • Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the prevention and treatment of EBV-associated post-transplant lymphomas
    • Liu Z, Savoldo B, Huls H, et al. Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the prevention and treatment of EBV-associated post-transplant lymphomas. Recent Results Cancer Res. 2002;159:123-133.
    • (2002) Recent Results Cancer Res , vol.159 , pp. 123-133
    • Liu, Z.1    Savoldo, B.2    Huls, H.3
  • 8
    • 33744788680 scopus 로고    scopus 로고
    • Safe adoptive transfer of virus-specific T-cell immunity for the treatment of systemic adenovirus infection after allogeneic stem cell transplantation
    • Feuchtinger T, Matthes-Martin S, Richard C, et al. Safe adoptive transfer of virus-specific T-cell immunity for the treatment of systemic adenovirus infection after allogeneic stem cell transplantation. Br J Haematol. 2006;134:64-76.
    • (2006) Br J Haematol , vol.134 , pp. 64-76
    • Feuchtinger, T.1    Matthes-Martin, S.2    Richard, C.3
  • 9
    • 0035282725 scopus 로고    scopus 로고
    • Direct visualization of cytomegalovirus-specific T-cell reconstitution after allogeneic stem cell transplantation
    • Cwynarski K, Ainsworth J, Cobbold M, et al. Direct visualization of cytomegalovirus-specific T-cell reconstitution after allogeneic stem cell transplantation. Blood. 2001;97: 1232-1240.
    • (2001) Blood , vol.97 , pp. 1232-1240
    • Cwynarski, K.1    Ainsworth, J.2    Cobbold, M.3
  • 10
    • 0033998352 scopus 로고    scopus 로고
    • Development of virus-specific CD4(+) T cells during primary cytomegalovirus infection
    • Rentenaar RJ, Gamadia LE, van DerHoek N, et al. Development of virus-specific CD4(+) T cells during primary cytomegalovirus infection. J Clin Invest. 2000;105:541-548.
    • (2000) J Clin Invest , vol.105 , pp. 541-548
    • Rentenaar, R.J.1    Gamadia, L.E.2    Van Derhoek, N.3
  • 11
    • 0030891988 scopus 로고    scopus 로고
    • + T cell frequencies by flow cytometry: Evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency
    • + T cell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency. J Clin Invest. 1997;99:1739-1750.
    • (1997) J Clin Invest , vol.99 , pp. 1739-1750
    • Waldrop, S.L.1    Pitcher, C.J.2    Peterson, D.M.3
  • 12
    • 0038353969 scopus 로고    scopus 로고
    • Ex vivo stimulation of cytomegalovirus (CMV)-specific T cells using CMV pp65-modified dendritic cells as stimulators
    • Carlsson B, Cheng WS, Totterman TH, et al. Ex vivo stimulation of cytomegalovirus (CMV)-specific T cells using CMV pp65-modified dendritic cells as stimulators. Br J Haematol. 2003;121:428-438.
    • (2003) Br J Haematol , vol.121 , pp. 428-438
    • Carlsson, B.1    Cheng, W.S.2    Totterman, T.H.3
  • 13
    • 20844437647 scopus 로고    scopus 로고
    • + T cells by a novel method using monocyte-derived HCMV-infected immature dendritic cells
    • + T cells by a novel method using monocyte-derived HCMV-infected immature dendritic cells. Eur J Immunol. 2005;35:1795-1804.
    • (2005) Eur J Immunol , vol.35 , pp. 1795-1804
    • Lozza, L.1    Lilleri, D.2    Percivalle, E.3
  • 14
    • 0038587735 scopus 로고    scopus 로고
    • Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells
    • Oelke M, Maus MV, Didiano D, et al. Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells. Nat Med. 2003;9: 619-624.
    • (2003) Nat Med , vol.9 , pp. 619-624
    • Oelke, M.1    Maus, M.V.2    Didiano, D.3
  • 15
    • 35448968937 scopus 로고    scopus 로고
    • Expansion of human cytomegalovirus-specific T lymphocytes from unfractionated peripheral blood mononuclear cells with artificial antigen-presenting cells
    • Paine A, Oelke M, Blasczyk R, et al. Expansion of human cytomegalovirus-specific T lymphocytes from unfractionated peripheral blood mononuclear cells with artificial antigen-presenting cells. Transfusion. 2007;47:2143-2152.
    • (2007) Transfusion , vol.47 , pp. 2143-2152
    • Paine, A.1    Oelke, M.2    Blasczyk, R.3
  • 16
    • 0035865520 scopus 로고    scopus 로고
    • Induction of cytomega-lovirus (CMV)-specific T-cell responses using dendritic cells pulsed with CMV antigen: A novel culture system free of live CMV virions
    • Peggs K, Verfuerth S, Mackinnon S. Induction of cytomega-lovirus (CMV)-specific T-cell responses using dendritic cells pulsed with CMV antigen: a novel culture system free of live CMV virions. Blood. 2001;97:994-1000.
    • (2001) Blood , vol.97 , pp. 994-1000
    • Peggs, K.1    Verfuerth, S.2    MacKinnon, S.3
  • 17
    • 0033230330 scopus 로고    scopus 로고
    • Simultaneous ex vivo expansion of cytomegalovirus and Epstein-Barr virus-specific cytotoxic T lymphocytes using B-lymphoblastoid cell lines expressing cytomegalovirus pp65
    • Sun Q, Pollok KE, Burton RL, et al. Simultaneous ex vivo expansion of cytomegalovirus and Epstein-Barr virus-specific cytotoxic T lymphocytes using B-lymphoblastoid cell lines expressing cytomegalovirus pp65. Blood. 1999;94:3242-3250.
    • (1999) Blood , vol.94 , pp. 3242-3250
    • Sun, Q.1    Pollok, K.E.2    Burton, R.L.3
  • 18
    • 0026047830 scopus 로고
    • Fine specificity of cellular immune responses in humans to human cytomegalo-virus immediate-early 1 protein
    • Alp NJ, Allport TD, Van Zanten J, et al. Fine specificity of cellular immune responses in humans to human cytomegalo-virus immediate-early 1 protein. J Virol. 1991;65:4812-4820.
    • (1991) J Virol , vol.65 , pp. 4812-4820
    • Alp, N.J.1    Allport, T.D.2    Van Zanten, J.3
  • 19
    • 0023874251 scopus 로고
    • Human cytomegalovirus-specific cytotoxic T cells: Their precursor frequency and stage specificity
    • Borysiewicz LK, Graham S, Hickling JK, et al. Human cytomegalovirus- specific cytotoxic T cells: their precursor frequency and stage specificity. Eur J Immunol. 1988;18: 269-275.
    • (1988) Eur J Immunol , vol.18 , pp. 269-275
    • Borysiewicz, L.K.1    Graham, S.2    Hickling, J.K.3
  • 20
    • 0345373932 scopus 로고    scopus 로고
    • +-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers
    • +-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers. J Virol. 2003;77:5226-5240.
    • (2003) J Virol , vol.77 , pp. 5226-5240
    • Elkington, R.1    Walker, S.2    Crough, T.3
  • 21
    • 0442326328 scopus 로고    scopus 로고
    • + T cell responses in children with congenital or postnatal human cytomegalovirus infection
    • + T cell responses in children with congenital or postnatal human cytomegalovirus infection. J Immunol. 2004;172:2256-2264.
    • (2004) J Immunol , vol.172 , pp. 2256-2264
    • Gibson, L.1    Piccinini, G.2    Lilleri, D.3
  • 22
    • 0033873474 scopus 로고    scopus 로고
    • Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors
    • Gillespie GM, Wills MR, Appay V, et al. Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors. J Virol. 2000;74:8140-8150.
    • (2000) J Virol , vol.74 , pp. 8140-8150
    • Gillespie, G.M.1    Wills, M.R.2    Appay, V.3
  • 23
    • 0037097657 scopus 로고    scopus 로고
    • Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals
    • Kern F, Bunde T, Faulhaber N, et al. Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals. J Infect Dis. 2002;185:1709-1716.
    • (2002) J Infect Dis , vol.185 , pp. 1709-1716
    • Kern, F.1    Bunde, T.2    Faulhaber, N.3
  • 25
    • 0036604316 scopus 로고    scopus 로고
    • Identification of naive or antigen-experienced human CD8(+) T cells by expression of costimulation and chemokine receptors: Analysis of the human cytomegalovirus-specific CD8(+) T cell response
    • Wills MR, Okecha G, Weekes MP, et al. Identification of naive or antigen-experienced human CD8(+) T cells by expression of costimulation and chemokine receptors: analysis of the human cytomegalovirus-specific CD8(+) T cell response. J Immunol. 2002;168:5455-5464.
    • (2002) J Immunol , vol.168 , pp. 5455-5464
    • Wills, M.R.1    Okecha, G.2    Weekes, M.P.3
  • 26
    • 24344489044 scopus 로고    scopus 로고
    • + T cells dominate the memory compartments of exposed subjects
    • + T cells dominate the memory compartments of exposed subjects. J Exp Med. 2005;202:673-685.
    • (2005) J Exp Med , vol.202 , pp. 673-685
    • Sylwester, A.W.1    Mitchell, B.L.2    Edgar, J.B.3
  • 27
    • 0029847916 scopus 로고    scopus 로고
    • The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: Frequency, specificity, and T-cell receptor usage of pp65-specific CTL
    • Wills MR, Carmichael AJ, Mynard K, et al. The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL. J Virol. 1996;70:7569-7579.
    • (1996) J Virol , vol.70 , pp. 7569-7579
    • Wills, M.R.1    Carmichael, A.J.2    Mynard, K.3
  • 28
    • 1942489201 scopus 로고    scopus 로고
    • + T-cell lines for adoptive transfer into recipients of allogeneic stem cell transplants
    • + T-cell lines for adoptive transfer into recipients of allogeneic stem cell transplants. Blood. 2004;103:3565-3572.
    • (2004) Blood , vol.103 , pp. 3565-3572
    • Rauser, G.1    Einsele, H.2    Sinzger, C.3
  • 29
    • 0033570373 scopus 로고    scopus 로고
    • Identification of three HLA-A*0201-restricted cytotoxic T cell epitopes in the cytomegalovirus protein pp65 that are conserved between eight strains of the virus
    • Solache A, Morgan CL, Dodi AI, et al. Identification of three HLA-A*0201-restricted cytotoxic T cell epitopes in the cytomegalovirus protein pp65 that are conserved between eight strains of the virus. J Immunol. 1999;163:5512-5518.
    • (1999) J Immunol , vol.163 , pp. 5512-5518
    • Solache, A.1    Morgan, C.L.2    Dodi, A.I.3
  • 30
    • 0035825604 scopus 로고    scopus 로고
    • Site-directed mutation in a conserved kinase domain of human cytomega-lovirus-pp65 with preservation of cytotoxic T lymphocyte targeting
    • Yao ZQ, Gallez-Hawkins G, Lomeli NA, et al. Site-directed mutation in a conserved kinase domain of human cytomega-lovirus-pp65 with preservation of cytotoxic T lymphocyte targeting. Vaccine. 2001;19:1628-1635.
    • (2001) Vaccine , vol.19 , pp. 1628-1635
    • Yao, Z.Q.1    Gallez-Hawkins, G.2    Lomeli, N.A.3
  • 31
    • 0032824127 scopus 로고    scopus 로고
    • Cloning of the human cytomegalovirus (HCMV) genome as an infectious bacterial artificial chromosome in Escherichia coli: A new approach for construction of HCMV mutants
    • Borst EM, Hahn G, Koszinowski UH, et al. Cloning of the human cytomegalovirus (HCMV) genome as an infectious bacterial artificial chromosome in Escherichia coli: a new approach for construction of HCMV mutants. J Virol. 1999; 73:8320-8329.
    • (1999) J Virol , vol.73 , pp. 8320-8329
    • Borst, E.M.1    Hahn, G.2    Koszinowski, U.H.3
  • 32
    • 44849094161 scopus 로고    scopus 로고
    • Rapid detection of JMH antibodies with recombinant Sema7A (CD108) protein and the particle gel immunoassay
    • Seltsam A, Agaylan A, Grueger D, et al. Rapid detection of JMH antibodies with recombinant Sema7A (CD108) protein and the particle gel immunoassay. Transfusion. 2008;48: 1151-1155.
    • (2008) Transfusion , vol.48 , pp. 1151-1155
    • Seltsam, A.1    Agaylan, A.2    Grueger, D.3
  • 33
    • 0037093102 scopus 로고    scopus 로고
    • Sensitive detection of human cytomegalovirus peptide-specific cytotoxic T-lympho-cyte responses by interferon-gamma-enzyme-linked immuno-spot assay and flow cytometry in healthy individuals and in patients after allogeneic stem cell transplantation
    • Hebart H, Daginik S, Stevanovic S, et al. Sensitive detection of human cytomegalovirus peptide-specific cytotoxic T-lympho-cyte responses by interferon-gamma-enzyme-linked immuno-spot assay and flow cytometry in healthy individuals and in patients after allogeneic stem cell transplantation. Blood. 2002;99:3830-3837.
    • (2002) Blood , vol.99 , pp. 3830-3837
    • Hebart, H.1    Daginik, S.2    Stevanovic, S.3
  • 34
    • 0346670260 scopus 로고    scopus 로고
    • Effector cell mediated cytotoxicity measured by intracellular Granzyme B release in HIV infected subjects
    • Mahajan SD, Aalinkeel R, Schwartz SA, et al. Effector cell mediated cytotoxicity measured by intracellular Granzyme B release in HIV infected subjects. Biol Proced Online. 2003; 5:182-188.
    • (2003) Biol Proced Online , vol.5 , pp. 182-188
    • Mahajan, S.D.1    Aalinkeel, R.2    Schwartz, S.A.3
  • 35
    • 33746496186 scopus 로고    scopus 로고
    • Tetanus toxoid provides efficient T-cell help for the induction of HA-1(H) cytotoxic T cells
    • Eiz-Vesper B, Horn PA, Daubert C, et al. Tetanus toxoid provides efficient T-cell help for the induction of HA-1(H) cytotoxic T cells. Transfusion. 2006;46:1210-1220.
    • (2006) Transfusion , vol.46 , pp. 1210-1220
    • Eiz-Vesper, B.1    Horn, P.A.2    Daubert, C.3
  • 36
    • 0023833207 scopus 로고
    • Human immune responses to major human cytomegalovirus glycoprotein complexes
    • Liu YN, Kari B, Gehrz RC. Human immune responses to major human cytomegalovirus glycoprotein complexes. J Virol. 1988;62:1066-1070.
    • (1988) J Virol , vol.62 , pp. 1066-1070
    • Liu, Y.N.1    Kari, B.2    Gehrz, R.C.3
  • 37
    • 44649153892 scopus 로고    scopus 로고
    • SYFPEITHI: Database for searching and T-cell epitope prediction
    • Schuler MM, Nastke MD, Stevanovikc S. SYFPEITHI: database for searching and T-cell epitope prediction. Methods Mol Biol. 2007;409:75-93.
    • (2007) Methods Mol Biol , vol.409 , pp. 75-93
    • Schuler, M.M.1    Nastke, M.D.2    Stevanovikc, S.3
  • 38
    • 40349084166 scopus 로고    scopus 로고
    • Prediction of epitopes in hemagglutinin and neuraminidase proteins of influenza A virus H5N1 strain: A clue for diagnostic and vaccine development
    • Somvanshi P, Singh V, Seth PK. Prediction of epitopes in hemagglutinin and neuraminidase proteins of influenza A virus H5N1 strain: a clue for diagnostic and vaccine development. Omics. 2008;12:61-69.
    • (2008) Omics , vol.12 , pp. 61-69
    • Somvanshi, P.1    Singh, V.2    Seth, P.K.3
  • 39
    • 34548711911 scopus 로고    scopus 로고
    • Synthetic multi-epitope peptides identified in silico induce protective immunity against multiple influenza serotypes
    • Stoloff GA, Caparros-Wanderley W. Synthetic multi-epitope peptides identified in silico induce protective immunity against multiple influenza serotypes. Eur J Immunol. 2007;37:2441-2449.
    • (2007) Eur J Immunol , vol.37 , pp. 2441-2449
    • Stoloff, G.A.1    Caparros-Wanderley, W.2
  • 40
    • 2442705373 scopus 로고    scopus 로고
    • Random screening of proteins for HLA-A*0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A*0201
    • Pelte C, Cherepnev G, Wang Y, et al. Random screening of proteins for HLA-A*0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A*0201. J Immunol. 2004;172:6783-6789.
    • (2004) J Immunol , vol.172 , pp. 6783-6789
    • Pelte, C.1    Cherepnev, G.2    Wang, Y.3
  • 41
    • 37349101246 scopus 로고    scopus 로고
    • Identification of hexon-specific CD4 and CD8 T-cell epitopes for vaccine and immunotherapy
    • Leen AM, Christin A, Khalil M, et al. Identification of hexon-specific CD4 and CD8 T-cell epitopes for vaccine and immunotherapy. J Virol. 2008;82:546-554.
    • (2008) J Virol , vol.82 , pp. 546-554
    • Leen, A.M.1    Christin, A.2    Khalil, M.3
  • 42
    • 0035437185 scopus 로고    scopus 로고
    • Differentiation of cytomegalovirus-specific CD8(+) T cells in healthy and immunosuppressed virus carriers
    • Gamadia LE, Rentenaar RJ, Baars PA, et al. Differentiation of cytomegalovirus-specific CD8(+) T cells in healthy and immunosuppressed virus carriers. Blood. 2001;98:754-761.
    • (2001) Blood , vol.98 , pp. 754-761
    • Gamadia, L.E.1    Rentenaar, R.J.2    Baars, P.A.3
  • 43
    • 0031881026 scopus 로고    scopus 로고
    • + T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1
    • + T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1. Nat Med. 1998; 4:953-956.
    • (1998) Nat Med , vol.4 , pp. 953-956
    • Komanduri, K.V.1    Viswanathan, M.N.2    Wieder, E.D.3


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