Human insulin microcrystals with lactose carriers for pulmonary delivery

Bioscience, Biotechnology and Biochemistry

Volumn 73, Issue 12, 2009, Pages 2576-2582

  Lim, Se Hwan ^a   Park, Hye Won ^a   Shin, Chang Hoon ^a   Kwon, Jai Hyun ^a   Kim, Chan Wha ^a  

^a Korea University   (South Korea)

Author keywords

Insulin; Lactate carriers; Microcrystal; Pulmonary delivery

Indexed keywords

BLOOD GLUCOSE CONCENTRATION; BLOOD GLUCOSE LEVEL; DOSAGE FORMS; DRY POWDERS; GLUCOSE LEVEL; HIGH MOLECULAR WEIGHT PROTEIN; INTRATRACHEAL; MICROCRYSTAL POWDER; MONO-DISPERSED; PARTICLE DIAMETERS; PREPARATION PROCESS; PULMONARY DELIVERY; RELATED COMPOUNDS; SPRAGUE-DAWLEY RATS;

BIOCHEMISTRY; BLOOD; GLUCOSE; MICROCRYSTALS; PHOTOGRAPHIC EMULSIONS; ZINC POWDER METALLURGY;

INSULIN;

DRUG CARRIER; INSULIN; LACTOSE;

ANIMAL; ARTICLE; BLOOD; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ADMINISTRATION ROUTE; GLUCOSE BLOOD LEVEL; HUMAN; HYPOGLYCEMIA; LUNG; MALE; METABOLISM; PARTICLE SIZE; RAT; SPRAGUE DAWLEY RAT; TRACHEA;

ANIMALS; BLOOD GLUCOSE; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG ADMINISTRATION ROUTES; DRUG CARRIERS; HUMANS; HYPOGLYCEMIA; INSULIN; LACTOSE; LUNG; MALE; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; TRACHEA;

RATTUS;

EID: 74349109735     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.80206     Document Type: Article

References (37)

1. Park SH, Kwon JH, Lim SH, Park HW, and Kim CW, Int. J. Pharm., 339, 205-212 (2007).
2. Lee HK, Kwon JH, Park SH, and Kim CW, Biosci. Biotechnol. Bio Chem., 70, 1003-1005 (2006).
3. Agu RU, Ugwoke MI, Armand M, Kinget R, and Verbeke N, Respir. Res., 2, 198-209 (2001).
4. Weibel ER, Bull. Eur. Physiopathol. Respir., 15, 999-1013 (1979).
5. Kwon JH and Kim CW, J. Cryst. Growth, 263, 536-543 (2004).
6. Kwon JH, Lee BH, Lee JJ, and Kim CW, Eur. J. Pharm. Sci., 22, 107-116 (2004).
7. Patton JS and Platz RM, Adv. Drug Deliv. Rev., 8, 179-196 (1992).
8. Patton JS, Trinchero P, and Platz RM, J. Control. Release, 28, 79-85 (1994).
9. Niven RW, Crit. Rev. Ther. Drug Carrier Syst., 12, 151-231 (1995).
10. Laube BL, Benedict GW, and Dobs AS, Chest, 114, 1734-1739 (1998).
11. Cefalu WT, Gelfand RA, and Koirides IA, Diabetes, 47 (Suppl. abstract), A61 (1998).
12. Skyler JS, Gelfand RA, and Kourides IA, Diabetes, 47 (Suppl. abstract), A61 (1998).
13. Choi SH, Kwon JH, and Kim CW, Biosci. Biotechnol. Bio Chem., 68, 749-752 (2004).
14. Hoffman AS, Stayton PS, Press O, Murthy N, Lackey CA, Cheung C, Black F, Campbell J, Fausto N, Kyriakides TR, and Bornstein P, Biotechnol. Bioprocess Eng., 6, 205-212 (2001).
15. Yeo Y, Baek N, and Park K, Biotechnol. Bioprocess Eng., 6, 213-230 (2001).
16. Patton JS, Bukar J, and Nagarajan S, Adv. Drug Deliv. Rev., 35, 235-247 (1999).
17. Sanchez A, Villamayor B, Guo Y, Mclver J, and Alonso MJ, Int. J. Pharm., 185, 255-266 (1999).
18. Rosa GD, Lommelli R, La Rotonda MI, Miro A, and Quaglia F, J. Control. Release, 69, 283-295 (2000).
19. Shekunov BY and York P, J. Cryst. Growth, 211, 122-136 (2000).
20. Newhouse MT and Corkery KJ, Respir. Care Clin. N. Am., 7, 261-275 (2001).
21. Johnson KA, Adv. Drug Deliv. Rev., 26, 3-15 (1997).
22. Yu Z, Roger TL, Hu J, Johnston KP, and Williams ROIII, Eur. J. Pharm. Bio Pharm., 54, 221-228 (2002).
23. Gonda I, J. Pharm. Sci., 89, 940-945 (2000).
24. Borgstrom L and Newman S, Int. J. Pharm., 97, 47-53 (1993).
25. Malcolmson RJ and Embleton JK, Pharm. Sci. Tech. Today, 1, 394-398 (1998).
26. de Boer AH, Hagedoorn P, Gjaltema D, Goede J, and Frijlink HW, Int. J. Pharm., 260, 187-200 (2003).
27. Podczeck F, Int. J. Pharm., 160, 119-130 (1998).
28. Larhrib H, Zeng XM, Martin GP, Marriott C, and Pritchard J, Int. J. Pharm., 191, 1-14 (1999).
29. Zeng XM, Martin GP, Marriott C, and Pritchard J, J. Pharm. Pharmacol., 52, 1211-1221 (2000).
30. Lankinen T, Patent, WO 99/34778 (1999).
31. Enna SJ and Schanker LS, Am. J. Physiol., 222, 409-414 (1972).
32. Brain JD, Knudson DE, Sorokin SP, and Davis MA, Environ. Res., 11, 13-33 (1976).
33. Hirai S, Yashiki T, and Mima H, Int. J. Pharm., 9, 165-172 (1981).
34. Verdonck E, Schaap K, and Thomas LC, Int. J. Pharm., 192, 3-20 (1999).
35. Gibson M, HIS Health Group, Englewood (2001).
36. Edman P, Bjork E, and Ryden L, J. Control. Release, 21, 165-172 (1992).
37. Lee WA, Narog GA, Patapoff TW, and Wang YJ, J. Pharm. Sci., 80, 725-729 (1991).