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Volumn 70, Issue 4, 2006, Pages 1003-1005

Enhanced hypoglycemic activity following intratracheal administration of insulin microcrystal suspension with injection adjuvant

Author keywords

Adjuvant; Instillation; Insulin; Lung; Microcrystal

Indexed keywords

BIOMATERIALS; BLOOD; GLUCOSE; GLYCEROL; HORMONES; ZINC;

EID: 33646138244     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.70.1003     Document Type: Article
Times cited : (8)

References (15)
  • 1
    • 0032240027 scopus 로고    scopus 로고
    • The lung as an alternative route of delivery for insulin in controlling postprandial glucose levels in patients with diabetes
    • Laube, B. L., Benedict, G. W., and Dobs, A. S., The lung as an alternative route of delivery for insulin in controlling postprandial glucose levels in patients with diabetes. Chest, 114, 1734-1739 (1998).
    • (1998) Chest , vol.114 , pp. 1734-1739
    • Laube, B.L.1    Benedict, G.W.2    Dobs, A.S.3
  • 3
    • 0035888373 scopus 로고    scopus 로고
    • Insulin therapies: Past, present and future
    • Pillai, O., and Panchagnula, R., Insulin therapies: past, present and future. Drug Discov. Today, 6, 1056-1061 (2001).
    • (2001) Drug Discov. Today , vol.6 , pp. 1056-1061
    • Pillai, O.1    Panchagnula, R.2
  • 4
    • 0027398639 scopus 로고
    • Pulmonary delivery of free and liposomal insulin
    • Liu, F. Y., Shao, Z., Kildsig, D. O., and Mitra, A. K., Pulmonary delivery of free and liposomal insulin. Pharm. Res., 10, 228-232 (1993).
    • (1993) Pharm. Res. , vol.10 , pp. 228-232
    • Liu, F.Y.1    Shao, Z.2    Kildsig, D.O.3    Mitra, A.K.4
  • 6
    • 33646126180 scopus 로고    scopus 로고
    • Korea Patent 0327597 (Feb. 23, 2002)
    • Kwon, J. H., and Kim, C. W., Korea Patent 0327597 (Feb. 23, 2002).
    • Kwon, J.H.1    Kim, C.W.2
  • 7
    • 1242263812 scopus 로고    scopus 로고
    • A novel insulin microcrystal preparation using a seed zone method
    • Kwon, J. H., and Kim, C. W., A novel insulin microcrystal preparation using a seed zone method. J. Crystal Growth, 263, 536-543 (2004).
    • (2004) J. Crystal Growth , vol.263 , pp. 536-543
    • Kwon, J.H.1    Kim, C.W.2
  • 8
    • 2442672006 scopus 로고    scopus 로고
    • Insulin microcrystal suspension as a long-acting formulation for pulmonary delivery
    • Kwon, J. H., Lee, B. H., Lee, J. J., and Kim, C. W., Insulin microcrystal suspension as a long-acting formulation for pulmonary delivery. Eur. J. Pharm. Sci., 22, 107-116 (2004).
    • (2004) Eur. J. Pharm. Sci. , vol.22 , pp. 107-116
    • Kwon, J.H.1    Lee, B.H.2    Lee, J.J.3    Kim, C.W.4
  • 10
    • 0019488704 scopus 로고
    • Effect of surfactants on the nasal absorption of insulin in rats
    • Hirai, S., Yashiki, T., and Mima, H., Effect of surfactants on the nasal absorption of insulin in rats. Int. J. Pharm., 9, 165-172 (1981).
    • (1981) Int. J. Pharm. , vol.9 , pp. 165-172
    • Hirai, S.1    Yashiki, T.2    Mima, H.3
  • 11
    • 0021767171 scopus 로고
    • Landmark perspective: Protamine insulin: Hagedorn's pioneering contribution to drug delivery in the management of diabetes
    • Felig, P., Landmark perspective: protamine insulin: Hagedorn's pioneering contribution to drug delivery in the management of diabetes. J. Am. Med. Assoc., 251, 393-396 (1984).
    • (1984) J. Am. Med. Assoc. , vol.251 , pp. 393-396
    • Felig, P.1
  • 12
    • 0036302005 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3beta by bivalent zinc ions: Insight into the insulin-mimetic action of zinc
    • Ilouz, R., Kaidanovich, O., Gurwitz, D., and Eldar-Finkelman, H., Inhibition of glycogen synthase kinase-3beta by bivalent zinc ions: insight into the insulin-mimetic action of zinc. Biochem. Biophys. Res. Commun., 295, 102-106 (2002).
    • (2002) Biochem. Biophys. Res. Commun. , vol.295 , pp. 102-106
    • Ilouz, R.1    Kaidanovich, O.2    Gurwitz, D.3    Eldar-Finkelman, H.4
  • 13
    • 2142812452 scopus 로고    scopus 로고
    • Insulinomimetic zinc(II) complexes with natural production: In vitro evaluation and blood glucose lowering effect in KK-Ay mice with type 2 diabetes mellitus
    • Kojima, Y., Yoshikawa, Y., Ueda, E., Ueda, R., Yamamoto, S., Kumekawa, K., Yanagihara, N., and Sakurai, H., Insulinomimetic zinc(II) complexes with natural production: in vitro evaluation and blood glucose lowering effect in KK-Ay mice with type 2 diabetes mellitus. Chem. Pharm. Bull., 51, 1006-1008 (2003).
    • (2003) Chem. Pharm. Bull. , vol.51 , pp. 1006-1008
    • Kojima, Y.1    Yoshikawa, Y.2    Ueda, E.3    Ueda, R.4    Yamamoto, S.5    Kumekawa, K.6    Yanagihara, N.7    Sakurai, H.8
  • 14
    • 0022977047 scopus 로고
    • Neutral insulin solutions physically stabilized by addition of Zn2+
    • Brange, J., Havelund, S., Hommel, E., Sorensen, E., and Kuhl, C., Neutral insulin solutions physically stabilized by addition of Zn2+. Diabet. Med., 3, 532-536 (1986).
    • (1986) Diabet. Med. , vol.3 , pp. 532-536
    • Brange, J.1    Havelund, S.2    Hommel, E.3    Sorensen, E.4    Kuhl, C.5
  • 15
    • 0345271837 scopus 로고
    • Insulin crystals: Chemical and biological studies on insulin crystals and insulin zinc suspensions
    • Schlichtkrull, J., Insulin crystals: chemical and biological studies on insulin crystals and insulin zinc suspensions. Acta Chem. Scand., 10, 1459 (1961).
    • (1961) Acta Chem. Scand. , vol.10 , pp. 1459
    • Schlichtkrull, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.