NMR dynamics and antibody recognition of the meningococcal lipidated outer membrane protein LP2086 in micellar solution

Biochimica et Biophysica Acta - Biomembranes

Volumn 1798, Issue 2, 2010, Pages 87-93

  Mascioni, Alessandro ^a   Moy, Franklin J ^a   McNeil, Lisa K ^b   Murphy, Ellen ^b   Bentley, Breagh E ^b   Camarda, Rosaria ^b   Dilts, Deborah A ^b   Fink, Pamela S ^b   Gusarova, Viktoria ^b   Hoiseth, Susan K ^b   Malakian, Karl ^a   Mininni, Terri ^b   Novikova, Elena ^b   Lin, Shuo ^b   Sigethy, Scott ^b   Zlotnick, Gary W ^b   Tsao, Désirée H H ^a  

^a PFIZER INC   (United States)

^b WYETH RESEARCH   (United States)

Author keywords

Detergent micelle; Dynamics; Factor H binding protein; Lipoprotein; LP2086; Membrane topology; Neisseria meningitidis; NMR spectroscopy; Outer membrane protein; Structure

Indexed keywords

FACTOR H BINDING PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; OUTER MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; BINDING KINETICS; CONTROLLED STUDY; MICELLE; MOLECULAR DYNAMICS; NEISSERIA MENINGITIDIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; HUMANS; LIPOPOLYSACCHARIDES; MICE; MICELLES; MODELS, MOLECULAR; NEISSERIA MENINGITIDIS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, TERTIARY;

BACTERIA (MICROORGANISMS); NEISSERIA MENINGITIDIS;

EID: 74249119955     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2009.09.021     Document Type: Article

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