Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: Crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide

Proteins: Structure, Function and Genetics

Volumn 29, Issue 1, 1997, Pages 113-125

  Van Den Elsen, Jean M H ^a,b   Herron, James N ^c   Hoogerhout, Peter ^d   Poolman, Jan T ^d   Boel, Edwin ^e   Logtenberg, Ton ^e   Wilting, Jaap ^f   Crommelin, Daan J A ^a   Kroon, Jan ^b   Gros, Piet ^b,f  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF UTAH   (United States)

^d NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^f UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Bactericidal antibody; Crystal structure; Neisseria meningitidis; Peptide fluorescein conjugate; PorA outer membrane protein

Indexed keywords

BACTERIUM ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT;

ANTIGEN RECOGNITION; ARTICLE; CRYSTAL STRUCTURE; IMMUNOGLOBULIN STRUCTURE; NEISSERIA MENINGITIDIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANTIBODIES, BACTERIAL; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, BACTERIAL; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; EPITOPES; FLUORESCEIN; FLUORESCEINS; IMMUNOGLOBULIN FAB FRAGMENTS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEISSERIA MENINGITIDIS; PEPTIDES; PORINS; PROTEIN BINDING; PROTEIN CONFORMATION;

BACTERIA (MICROORGANISMS); NEISSERIA MENINGITIDIS; STAPHYLOCOCCUS PHAGE 187;

EID: 0030931370     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(199709)29:1<113::AID-PROT9>3.0.CO;2-G     Document Type: Article

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