Cross-reactivity of antibodies against PorA after vaccination with a meningococcal B outer membrane vesicle vaccine

Infection and Immunity

Volumn 71, Issue 4, 2003, Pages 1650-1655

  Vermont, C L ^a,b   Van Dijken, H H ^a   Kuipers, A J ^a   Van Limpt, C J P ^a   Keijzers, W C M ^c   Van der Ende, A ^c   De Groot, R ^b   Van Alphen, L ^a   Van den Dobbelsteen, G P J M ^a  

^a NETHERLANDS VACCINE INSTITUTE   (Netherlands)

^b SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^c NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; CROSS REACTING ANTIBODY; HEXAMEN; MENINGOCOCCUS VACCINE; MONOMEN; PORIN; PORIN A; UNCLASSIFIED DRUG;

ANTIBODY RESPONSE; ARTICLE; BACTERIUM ISOLATE; CHILD; CLINICAL TRIAL; CROSS REACTION; DRUG RESPONSE; HUMAN; HUMAN TISSUE; IMMUNOGENICITY; NETHERLANDS; NONHUMAN; OUTER MEMBRANE; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; SERUM; SERUM BACTERICIDAL ACTIVITY; VACCINATION;

AMINO ACID SEQUENCE; ANTIBODIES, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; CHILD; CHILD, PRESCHOOL; CROSS REACTIONS; HUMANS; MENINGOCOCCAL INFECTIONS; MENINGOCOCCAL VACCINES; MOLECULAR SEQUENCE DATA; NEISSERIA MENINGITIDIS, SEROGROUP B; PORINS; SEQUENCE ANALYSIS, DNA; VACCINATION;

EID: 0037379540     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.4.1650-1655.2003     Document Type: Article

References (15)

1. Bart, A., J. Dankert, and A. van der Ende. 1999. Antigenic variation of the class I outer membrane protein in hyperendemic Neisseria meningitidis strains in The Netherlands. Infect. Immun. 67:3842-3846.
2. Cartwright, K., R. Morris, H. Rumke, A. Fox, R. Borrow, N. Begg, P. Richmond, and J. Poolman. 1999. Immunogenicity and reactogenicity in UK infants of a novel meningococcal vesicle vaccine containing multiple class 1 (PorA) outer membrane proteins. Vaccine 17:2612-2619.
3. de Kleijn, E. D., R. de Groot, J. Labadie, A. B. Lafeber, G. van den Dobbelsteen, L. van Alphen, H. van Dijken, B. Kuipers, G. W. van Omme, M. Wala, R. Juttmann, and H. C. Rumke. 2000.,Immunogenicity and safety of a hexavalent meningococcal outer-membrane-vesicle vaccine in children of 2-3 and 7-8 years of age. Vaccine 18:1456-1466.
4. de Kleijn, E. D., R. de Groot, A. B. Lafeber, J. Labadie, C. J. van Limpt, J. Visser, G. A. Berbers, L. van Alphen, and H. C. Rumke. 2001. Prevention of meningococcal serogroup B infections in children: a protein-based vaccine induces immunologic memory. J. Infect. Dis. 184:98-102.
5. de Kleijn, E. D., R. de Groot, A. B. Lafeber, J. Labadie, K. C. van Limpt, J. Visser, G. A. Berbers, L. van Alphen, and H. C. Rumke. 2000. Immunogenicity and safety of monovalent p1.7(h),4 meningococcal outer membrane vesicle vaccine in toddlers: comparison of two vaccination schedules and two vaccine formulations. Vaccine 19:1141-1148.
6. Kuipers, B., G. van den Dobbelsteen, E. Wedege, A. van Alphen. 2001. Serological characterization, p. 131-145. In A. J. Pollard and M. C. J. Maiden (ed.), Meningococcal disease: methods and protocols, vol. 67. Humana Press, Totowa, N.J.
7. Maiden, M. C., J. Russell, J. Suker, and I. M. Feavers. 1999. Neisseria meningitidis subtype nomenclature. Clin. Diagn. Lab. Immunol. 6:771-772.
8. Martin, S. L., R. Borrow, P. van der Ley, M. Dawson, A. J. Fox, and K. A. Cartwright. 2000. Effect of sequence variation in meningococcal PorA outer membrane protein on the effectiveness of a hexavalent PorA outer membrane vesicle vaccine. Vaccine 18:2476-2481.
9. Morley, S. L., M. J. Cole, C. A. Ison, M. A. Camaraza, F. Sotolongo, N. I. Cuevas, M. Carbonero, H. C. Campa, G. Sierra, and M. Levin. 2001. Immunogenicity of a serogroup B meningococcal vaccine against multiple Neisseria meningitidis strains in infants. Pediatr. Infect. Dis. J. 20:1054-1061.
10. Netherlands Reference Laboratory for Bacterial Meningitis. 2000. Bacterial meningitis in the Netherlands. Annual report. Netherlands Reference Laboratory for Bacterial Meningitis, Amsterdam, The Netherlands.
11. Peeters, C. C., H. C. Rumke, L. C. Sundermann, E. M. Rouppe van der Voort, J. Meulenbelt, M. Schuller, A. J. Kuipers, P. van der Ley, and J. T. Poolman. 1996. Phase I clinical trial with a hexavalent PorA containing meningococcal outer membrane vesicle vaccine. Vaccine 14:1009-1015.
12. Perkins, B. A., K. Jonsdottir, H. Briem, E. Griffiths, B. D. Plikaytis, E. A. Hoiby, E. Rosenqvist, J. Holst, H. Nokleby, F. Sotolongo, G. Sierra, H. C. Campa, G. M. Carlone, D. Williams, J. Dykes, D. Kapczynski, E. Tikhomirov, J. D. Wenger, and C. V. Broome. 1998. Immunogenicity of two efficacious outer membrane protein-based serogroup B meningococcal vaccines among young adults in Iceland. J. Infect. Dis. 177:683-691.
13. Rosenqvist, E., E. A. Hoiby, E. Wedege, B. Kusecek, and M. Achtman. 1993. The 5C protein of Neisseria meningitidis is highly immunogenic in humans and induces bactericidal antibodies. J. Infect. Dis. 167:1065-1073.
14. Tappero, J. W., R. Lagos, A. M. Ballesteros, B. Plikaytis, D. Williams, J. Dykes, L. L. Gheesling, G. M. Carlone, E. A. Hoiby, J. Holst, H. Nokleby, E. Rosenqvist, G. Sierra, C. Campa, F. Sotolongo, J. Vega, J. Garcia, P. Herrera, J. T. Poolman, and B. A. Perkins. 1999. Immunogenicity of 2 serogroup B outer-membrane protein meningococcal vaccines: a randomized controlled trial in Chile. JAMA 281:1520-1527.
15. van der Voort, E. R., P. van der Ley, J. van der Biezen, S. George, O. Tunnela, H. van Dijken, B. Kuipers, and J. Poolman. 1996. Specificity of human bactericidal antibodies against PorA P1.7,16 induced with a hexavalent meningococcal outer membrane vesicle vaccine. Infect. Immun. 64:2745-2751.