Population pharmacokinetics and pharmacodynamics of cinaciguat, a soluble guanylate cyclase activator, in patients with acute decompensated heart failure

Clinical Pharmacokinetics

Volumn 49, Issue 2, 2010, Pages 119-129

  Frey, Reiner ^a   Mueck, Wolfgang ^a  

^a BAYER PHARMA AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 [[4 CARBOXYBUTYL[2 [(4 PHENETHYLBENZYL)OXY]PHENETHYL]AMINO]METHYL]BENZOIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIURETIC AGENT; RAMIPRIL;

ACUTE HEART FAILURE; ADULT; AGEISM; ARTICLE; BODY WEIGHT; COMPARTMENT MODEL; COMPUTER PROGRAM; DIASTOLIC BLOOD PRESSURE; DISTRIBUTION VOLUME; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE TITRATION; FEMALE; HEART OUTPUT; HEART RIGHT ATRIUM PRESSURE; HEART STROKE VOLUME; HEMODYNAMICS; HUMAN; KIDNEY FUNCTION; LUNG ARTERY PRESSURE; LUNG VASCULAR RESISTANCE; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PREDICTION; PRIORITY JOURNAL; PULMONARY ARTERY OCCLUSION PRESSURE; SYSTEMIC VASCULAR RESISTANCE; SYSTOLIC BLOOD PRESSURE; TREATMENT DURATION;

ACUTE DISEASE; AGED; BENZOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GUANYLATE CYCLASE; HEART FAILURE; HEMODYNAMICS; HUMANS; MALE; NONLINEAR DYNAMICS; VASODILATOR AGENTS;

EID: 74249113027     PISSN: 03125963     EISSN: 11791926     Source Type: Journal    
DOI: 10.2165/11317590-000000000-00000     Document Type: Article

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