메뉴 건너뛰기




Volumn 57, Issue 8, 2009, Pages 870-873

Pharmacologic therapies on the horizon for acute lung injury/acute respiratory distress syndrome

Author keywords

Activated protein C; ALI ARDS; Permeability; Sphingosine 1 phosphate; Statins

Indexed keywords

ACTIVATED PROTEIN C; ENDOTHELIAL PROTEIN C RECEPTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MYOSIN LIGHT CHAIN KINASE; RAC PROTEIN; RHO FACTOR; RHO KINASE; SIMVASTATIN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR;

EID: 74249109059     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: 10.2310/JIM.0b013e3181c04681     Document Type: Conference Paper
Times cited : (7)

References (22)
  • 1
    • 0037393019 scopus 로고    scopus 로고
    • Epidemiology of acute lung injury
    • Rubenfeld GD. Epidemiology of acute lung injury. Crit Care Med. 2003;31:S276-S284.
    • (2003) Crit Care Med. , vol.31
    • Rubenfeld, G.D.1
  • 2
    • 0025323679 scopus 로고
    • Lung edema caused by high peak inspiratory pressures in dogs. Role of increased microvascular filtration pressure and permeability
    • Parker JC, Hernandez LA, Longenecker GL, et al. Lung edema caused by high peak inspiratory pressures in dogs. Role of increased microvascular filtration pressure and permeability. Am Rev Respir Dis. 1990;142:321-328.
    • (1990) Am Rev Respir Dis. , vol.142 , pp. 321-328
    • Parker, J.C.1    Hernandez, L.A.2    Longenecker, G.L.3
  • 3
    • 0016282065 scopus 로고
    • Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures. Protection by positive end-expiratory pressure
    • Webb HH, Tierney DF. Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures. Protection by positive end-expiratory pressure. Am Rev Respir Dis. 1974;110:556-565.
    • (1974) Am Rev Respir Dis. , vol.110 , pp. 556-565
    • Webb, H.H.1    Tierney, D.F.2
  • 4
    • 0025034324 scopus 로고
    • Lung overexpansion increases pulmonary microvascular protein permeability in young lambs
    • Carlton DP, Cummings JJ, Scheerer RG, et al. Lung overexpansion increases pulmonary microvascular protein permeability in young lambs. J Appl Physiol. 1990;69:577-583.
    • (1990) J Appl Physiol. , vol.69 , pp. 577-583
    • Carlton, D.P.1    Cummings, J.J.2    Scheerer, R.G.3
  • 5
    • 0023937536 scopus 로고
    • High inflation pressure pulmonary edema. Respective effects of high airway pressure, high tidal volume, and positive end-expiratory pressure
    • Dreyfuss D, Soler P, Basset G, et al. High inflation pressure pulmonary edema. Respective effects of high airway pressure, high tidal volume, and positive end-expiratory pressure. Am Rev Respir Dis. 1988;137: 1159-1164.
    • (1988) Am Rev Respir Dis. , vol.137 , pp. 1159-1164
    • Dreyfuss, D.1    Soler, P.2    Basset, G.3
  • 6
    • 0033675578 scopus 로고    scopus 로고
    • Inhibitors of myosin light chain kinase and phosphodiesterase reduce ventilator-induced lung injury
    • Parker JC. Inhibitors of myosin light chain kinase and phosphodiesterase reduce ventilator-induced lung injury. J Appl Physiol. 2000;89:2241-2248.
    • (2000) J Appl Physiol. , vol.89 , pp. 2241-2248
    • Parker, J.C.1
  • 7
    • 0029805917 scopus 로고    scopus 로고
    • Protein phosphatase 2A in stretch-induced endothelial cell proliferation
    • Murata K, Mills I, Sumpio BE. Protein phosphatase 2A in stretch-induced endothelial cell proliferation. J Cell Biochem. 1996;63:311-319.
    • (1996) J Cell Biochem. , vol.63 , pp. 311-319
    • Murata, K.1    Mills, I.2    Sumpio, B.E.3
  • 8
    • 0343893748 scopus 로고    scopus 로고
    • Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome
    • The Acute Respiratory Distress Syndrome Network
    • The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med. 2000;342:1301-1308.
    • (2000) N Engl J Med. , vol.342 , pp. 1301-1308
  • 9
    • 0034807581 scopus 로고    scopus 로고
    • Cytoskeletal regulation of pulmonary vascular permeability
    • Dudek SM, Garcia JG. Cytoskeletal regulation of pulmonary vascular permeability. J Appl Physiol. 2001;91:1487-1500.
    • (2001) J Appl Physiol. , vol.91 , pp. 1487-1500
    • Dudek, S.M.1    Garcia, J.G.2
  • 10
    • 0037636489 scopus 로고    scopus 로고
    • Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products
    • Schaphorst KL, Chiang E, Jacobs KN, et al. Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products. Am J Physiol Lung Cell Mol Physiol. 2003;285:L258-L267.
    • (2003) Am J Physiol Lung Cell Mol Physiol. , vol.285
    • Schaphorst, K.L.1    Chiang, E.2    Jacobs, K.N.3
  • 11
    • 2642580994 scopus 로고    scopus 로고
    • Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: Roles for cortactin and myosin light chain kinase
    • Dudek SM, Jacobson JR, Chiang ET, et al. Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: Roles for cortactin and myosin light chain kinase. J Biol Chem. 2004;279: 24692-24700.
    • (2004) J Biol Chem. , vol.279 , pp. 24692-24700
    • Dudek, S.M.1    Jacobson, J.R.2    Chiang, E.T.3
  • 13
    • 7044241285 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury
    • McVerry BJ, Peng X, Hassoun PM, et al. Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury. Am J Respir Crit Care Med. 2004;170:987-993.
    • (2004) Am J Respir Crit Care Med. , vol.170 , pp. 987-993
    • McVerry, B.J.1    Peng, X.2    Hassoun, P.M.3
  • 14
    • 0035826096 scopus 로고    scopus 로고
    • Efficacy and safety of recombinant human activated protein C for severe sepsis
    • Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001;344:699-709.
    • (2001) N Engl J Med. , vol.344 , pp. 699-709
    • Bernard, G.R.1    Vincent, J.L.2    Laterre, P.F.3
  • 15
    • 20444443508 scopus 로고    scopus 로고
    • Activated protein C mediates novel lung endothelial barrier enhancement: Role ofsphingosine 1-phosphate receptor transactivation
    • Finigan JH, Dudek SM, Singleton PA, et al. Activated protein C mediates novel lung endothelial barrier enhancement: role ofsphingosine 1-phosphate receptor transactivation. J Biol Chem. 2005;280:17286-17293.
    • (2005) J Biol Chem. , vol.280 , pp. 17286-17293
    • Finigan, J.H.1    Dudek, S.M.2    Singleton, P.A.3
  • 16
    • 2342640996 scopus 로고    scopus 로고
    • Cytoskeletal activation and altered gene expression in endothelial barrier regulation by simvastatin
    • Jacobson JR, Dudek SM, Birukov KG, et al. Cytoskeletal activation and altered gene expression in endothelial barrier regulation by simvastatin. Am J Respir Cell Mol Biol. 2004;30:662-670.
    • (2004) Am J Respir Cell Mol Biol. , vol.30 , pp. 662-670
    • Jacobson, J.R.1    Dudek, S.M.2    Birukov, K.G.3
  • 17
    • 26644442350 scopus 로고    scopus 로고
    • Mechanisms of statin-mediated inhibition of small G-protein function
    • Cordle A, Koenigsknecht-Talboo J, Wilkinson B, et al. Mechanisms of statin-mediated inhibition of small G-protein function. J Biol Chem. 2005;280:34202-34209.
    • (2005) J Biol Chem. , vol.280 , pp. 34202-34209
    • Cordle, A.1    Koenigsknecht-Talboo, J.2    Wilkinson, B.3
  • 18
    • 56149098127 scopus 로고    scopus 로고
    • Endothelial barrier protection by simvastatin: Rho GTPase regulation and NADPH oxidase inhibition
    • ChenW, Pendyala S, Natarajan V, et al. Endothelial barrier protection by simvastatin: Rho GTPase regulation and NADPH oxidase inhibition. Am J Physiol Lung Cell Mol Physiol. 2008;295:L575-L583.
    • (2008) Am J Physiol Lung Cell Mol Physiol. , vol.295
    • Chen, W.1    Pendyala, S.2    Natarajan, V.3
  • 19
    • 0033826581 scopus 로고    scopus 로고
    • The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals
    • Kureishi Y, Luo Z, Shiojima I, et al. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat Med. 2000;6:1004-1010.
    • (2000) Nat Med. , vol.6 , pp. 1004-1010
    • Kureishi, Y.1    Luo, Z.2    Shiojima, I.3
  • 20
    • 0037178736 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors interfere with angiogenesis by inhibiting the geranylgeranylation of RhoA
    • Park HJ, Kong D, Iruela-Arispe L, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors interfere with angiogenesis by inhibiting the geranylgeranylation of RhoA. Circ Res. 2002;91:143-150.
    • (2002) Circ Res. , vol.91 , pp. 143-150
    • Park, H.J.1    Kong, D.2    Iruela-Arispe, L.3
  • 21
    • 0345687500 scopus 로고    scopus 로고
    • Positional control of cell fate through joint integrin/receptor protein kinase signaling
    • Giancotti FG, Tarone G. Positional control of cell fate through joint integrin/receptor protein kinase signaling. Annu Rev Cell Dev Biol. 2003;19:173-206.
    • (2003) Annu Rev Cell Dev Biol. , vol.19 , pp. 173-206
    • Giancotti, F.G.1    Tarone, G.2
  • 22
    • 18844394239 scopus 로고    scopus 로고
    • Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury
    • Jacobson JR, Barnard JW, Grigoryev DN, et al. Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury. Am J Physiol Lung Cell Mol Physiol. 2005;288:L1026-L1032.
    • (2005) Am J Physiol Lung Cell Mol Physiol. , vol.288
    • Jacobson, J.R.1    Barnard, J.W.2    Grigoryev, D.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.