Cytoprotective role of astaxanthin against glycated protein/iron chelate-induced toxicity in human umbilical vein endothelial cells

Phytotherapy Research

Volumn 24, Issue 1, 2010, Pages 54-59

  Nishigaki, Ikuo ^a   Rajendran, Peramaiyan ^a   Venugopal, Ramachandran ^a   Ekambaram, Gnapathy ^a   Sakthisekaran, Dhanapal ^b   Nishigaki, Yutaka ^c  

^a NPO International Laboratory of Biochemistry   (Japan)

^b UNIVERSITY OF MADRAS   (India)

^c TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Antioxidant enzymes; Astaxanthin; Glycated protein; HUVEC; Iron

Indexed keywords

ANTIOXIDANT; ASTAXANTHIN; GLUCOSE; GLYCOSYLATED PROTEIN; IRON CHELATE; LIPID PEROXIDE; REACTIVE OXYGEN METABOLITE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL CULTURE; CELL PROTECTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INCUBATION TIME; LIPID PEROXIDATION; UMBILICAL VEIN;

ANTIOXIDANTS; CELL LINE; ENDOTHELIAL CELLS; HUMANS; IRON CHELATING AGENTS; LIPID PEROXIDATION; LIPID PEROXIDES; OXIDATIVE STRESS; OXIDOREDUCTASES; REACTIVE OXYGEN SPECIES; UMBILICAL VEINS; XANTHOPHYLLS;

ALGAE; BOVINAE;

EID: 74249108897     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2867     Document Type: Article

References (50)

1. Ahmed N. 2005 Advanced glycation endproducts - role in pathology of diabetic complications. Diabetes Res Clin Pract 67: 3-21.
2. American Diabetic Association: Guidelines. 2005. Standards of medical care in diabetes. Diabetes Care 28: S4-S36.
3. Augusti PR. Conterato GMM, Somacal S, Sobieski R, Spohr PR, Torres JV. 2008. Effect of astaxanthin on kidney function impairment and oxidative stress induced by mercuric chloride in rats. Food Chem Toxicol 46: 212-219.
4. 2+-loaded liposomes: scavenging oxyradicals or changing membrane permeability. Biochem Biophys Res Commun 288: 225-232.
5. Bernstein PS, Khachik F, Carvalho LS, Muir GJ, Zhao DY, Katz NB. 2001. Identification and quantification of carotenoids and their metabolites in the tissues of the human eye. Exp Eye Res 72: 215-223.
6. Bonnefont-Rousselot D. 2002. Glucose and reactive oxygen species. Curr Opin Clin Nutr Metab Care 5: 561-568.
7. Brownlee M. 2001. Biochemistry and molecular cell biology of diabetic complications. Nature 414: 813-820.
8. Chew BP, Park JS, Wong MW, Wong TS. 1999. A comparison of the anticancer activities of dietary beta-carotene, canthaxanthin and astaxanthin in mice in vivo. Anticancer Res 19: 1849-1853.
9. Elgawish A, Glomb M, Friedlander M, Monnier VM. 1996. Involvement of hydrogen peroxide in collagen cross-linking by high glucose in vitro and in vivo. J Biol Chem 271: 12964-12971.
10. Ghazi H, Ushio S, Hirozo G, Kinzo Mo, Hiroshi W. 2006. Astaxanthin, a carotenoid with potential in human health and nutrition. J Nat Prod 69: 443-449.
11. Gong GQ, Liu TZ, Li LW. 2001. Antioxidative activity of crocetin in vitro. J China Pharm Univ 32: 306-309.
12. Goto S, Kogure K, Abe K et al. 2001. Efficient radical trapping at the surface and inside the phospholipid membrane is responsible for highly potent antiperoxidative activity of the carotenoid astaxanthin. Biochim Biophys Acta 1512: 251-258.
13. Guillermo Z, Fortuño A, Díez J. 2006. Oxidative stress and atherosclerosis in early chronic kidney disease. Nephrol Dial Transplant 21: 2686-2690.
14. Halliwell B. 2005. Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Aging 18: 685-716.
15. Halliwell B, Gutteridge JMC. 1999. Free Radicals in Biology and Medicine. Oxford University Press: New York, 936.
16. Halliwell B, Whiteman M. 2004. Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean. Br J Pharmacol 142: 231-255.
17. Heistad DD. 2005. Oxidative stress and vascular disease. Arterioscler Thromb Vasc Biol 26: 689-695.
18. Hunt JV, Bottoms MA, Mitchinson MJ. 1993. Oxidative alterations in the experimental glycation model of diabetes mellitus are due to protein-glucose adduct oxidation. Biochem J 291: 529-535.
19. Ikuo Nishigaki, Dmitrovskii AA, Water M, Kunio Yagi. 1994. Suppressive Effect of Astaxathin on lipid peroxidation induced in rats. J Clin Biochem Nutr 16: 161-164.
20. Isabella Dalle-D, Rossi R, Colombo R, Giustarini D, Milzani A. 2006. Biomarkers of oxidative damage in human disease. Clin Chem 52: 601-623.
21. Jagetia GG, Reddy TK, Venkatesha VA, Rajendra K. 2004. Influence of naringin on ferric iron induced oxidative damage in vitro. Clin Chim Acta 347: 189-197.
22. Kim J, Choi S, Choi S, Kim H, Chang H. 2005a. Suppressive effect of astaxanthin isolated from the Xanthophyllomyces dendrorhous mutant on ethanol-induced gastric mucosal injury in rats. Biosci Biotechnol Biochem 69: 1300-1305.
23. Kim J, Kim Y, Song G, Park J, Chang H. 2005b. Protective effect of astaxanthin on naproxen-induced gastric antral ulceration in rats. Eur J Pharmacol 514: 53-59.
24. Kurashige M, Okimasu E, Inoue M, Utsumi K. 1990. Inhibition of oxidative injury of biological membranes by astaxanthin. Physiol Chem Phys Med 22: 27-38.
25. Liu SX, Hou FF, Guo ZJ et al. 2006. Advanced oxidation protein products accelerate atherosclerosis through promoting oxidative stress and inflammation. Arterioscler Thromb Vasc Biol 26: 1156-1162.
26. Liu WS, Wu JY. 2006. Hydrogen peroxide-induced astaxanthin biosynthesis and catalase activity in Xanthophyllomyces dendrorhous. Appl Microbiol Cell Phys 73: 663-668.
27. Lowry OH, Rosebrough NT, Farr AL, Randall RT. 1971. Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275.
28. Lyons N, O'Brien N. 2002. Modulatory effects of an algal extract containing astaxanthin on UVA-irradiated cells in culture. J Dermatol Sci 30: 73-84.
29. Maritim AC, Sanders RA, Watkins JB. 2003. Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol 17: 24-38.
30. Naguib YMA. 2000. Antioxidant activity of astaxanthin and related carotenoids. J Agric Food Chem 48: 1150-1154.
31. Nishigaki I, Tanimoto A, Sasaguri Y, Yagi K. 1998. Glycated protein-iron chelate increases lipid peroxide level in cultured aortic endothelial and smooth muscle cells . Biochem Mol Int 45: 519-526.
32. Oya T, Osawa T, Kawakishi S. 1997. Spice constituents scavenging free radicals and inhibiting pentosidine formation in a model system. Biosci Biotechnol Biochem 61: 263-266.
33. Pannala AS, Rice-Evans C, Sampson J, Singh S. 1998. Interaction of peroxynitrite with carotenoids and tocopherols within low density lipoprotein. FEBS Lett 423: 297-301.
34. Ruderman NB, Williamson JR, Brownlee M. 1992. Glucose and diabetic vascular disease. FASEB J 6: 2905-2914.
35. Schroeder WA, Johnson EA. 1993. Antioxidant role of carotenoids in Phaffia rhodozyma. J Gen Microbiol 139: 907-912.
36. Schroeder WA, Johnson EA. 1995. Singlet oxygen and peroxyl radicals regulate carotenoid biosynthesis in Phaffia rhodozyma. J Biol Chem 270: 18374-18379.
37. Seval Y, Ahmet A, Engin S, Izzet K, Songul O. 2006. Protective effect of lycopene on adriamycin-induced cardiotoxicity and nephrotoxicity. Toxicology 218: 164-171.
38. Sies H. 1991. Oxidative Stress: Oxidants and Antioxidants. Academic Press: New York.
39. Stahl W, Sies H. 2003. Antioxidant activity of carotenoids. Mol Aspects Med 24: 345-351.
40. Stephens JW, Gable DR, Hurel SJ, Miller GJ, Cooper JA, Humphries SE. 2006. Increased plasma markers of oxidative stress are associated with coronary heart disease in males with diabetes mellitus and with 10-year risk in a prospective sample of males. Clin Chem 52: 446-452.
41. Takagi Y, Kashiwagi A, Tanaka Y, Asahina T, Kikkawa R, Shigeta Y. 1995. Significance of fructose-induced protein oxidation and formation of advanced glycation end products. J Diabetes Complicat 9: 87-91.
42. Uchiyama K, Naito Y, Hasegawa G, Nakamura N, Takahashi J, Yoshikawa T. 2002. Astaxanthin protects beta-cells against glucose toxicity in diabetic db/db mice. Redox Rep 7: 290-293.
43. Ulicna O, Vancova O, Bozek P et al. 2006. Rooibos tea (Aspalathus linearis) partially prevents oxidative stress in streptozotocininduced diabetic rats. Physiol Res 55: 157-164.
44. Vlassara H, Palace MR. 2002. Diabetes and advanced glycation endproducts. J Intern Med 251: 87-101.
45. Wieruszwysocka B, Wysocki H, Byks H, Zozulinska D, Wykretowicz A, Kazierczak M. 1995. Metabolic control quality and free radical activity in diabetic patients. Diabetes Res Clin Pract 27: 193-197.
46. Wolff SP. 1993. Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the etiology of diabetes mellitus and complications. Br Med Bull 49: 642-652.
47. Wu CH, Yen GC. 2005. Inhibitory effect of naturally occurring flavonoids on the formation of advanced glycation endproducts. J Agric Food Chem 253: 3167-3173.
48. Wu T, Liao J, Hou W, Huang F, Maher TJ, Hu C. 2006. Astaxanthin protects against oxidative stress and calcium-induced porcine lens protein degradation. J Agric Food Chem 54: 2418-2423.
49. Yagi K, Ohtsuks K, Ohishi N. 1985. Lipid peroxidation caused by chiform-ferric chelate in cultured neural retinal cells. Experientia 441: 1561-1563.
50. Yim HS, Kang SO, Hah YC, Chock PB, Yim MB. 1995. Free radicals generated during the glycation reaction of amino acids by methylglyoxal. A model study of protein-cross-linked free radicals. J Biol Chem 270: 28228-28233.