Stabilization by meglumine of an amine compound degraded by formaldehyde in tablets

International Journal of Pharmaceutics

Volumn 386, Issue 1-2, 2010, Pages 195-200

  Fujita, Megumi ^a   Ueda, Tomohiko ^a   Iwata, Motokazu ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

Degradation; Formaldehyde; Meglumine; Stabilization; Tablet

Indexed keywords

[3 [[[(3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1H INDOL 7 YLOXY]ACETIC ACID; [[(3 CHLOROPHENYL) 2 HYDROXYETHYL]METHYL 1,2,3,4 TETRAHYDRO BETA CARBOLINE 8 YLOXY]ACETIC ACID; AD 9889; AJ 9677; AMINE; ANTIDIABETIC AGENT; CARBON; FORMALDEHYDE; MEGLUMINE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL INTERACTION; CHEMICAL REACTION; DEGRADATION; DRUG STABILITY; DRUG STORAGE; PRIORITY JOURNAL; TABLET FORMULATION;

ACETIC ACIDS; AMINES; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; DRUG STORAGE; EXCIPIENTS; FORMALDEHYDE; HYPOGLYCEMIC AGENTS; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; MEGLUMINE; TABLETS; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; TIME FACTORS;

EID: 74149093543     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.11.017     Document Type: Article

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