Generation of formaldehyde by pharmaceutical excipients and its absorption by meglumine

Chemical and Pharmaceutical Bulletin

Volumn 57, Issue 10, 2009, Pages 1096-1099

  Fujita, Megumi ^a   Ueda, Tomohiko ^a   Handa, Tetsurou ^b  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Amine; Degradation; Excipient; Formaldehyde; Meglumine

Indexed keywords

AEROSIL; ALANINE; ARGININE; CEOLUS PH 101; EXCIPIENT; FORMALDEHYDE; HYDROXYPROPYLCELLULOSE; LACTOSE; MAGNESIUM STEARATE; MANNITOL; MEGLUMINE; MICROCRYSTALLINE CELLULOSE; PHARMATOSE 200M; PROLINE; SILICIC ACID; UNCLASSIFIED DRUG;

ABSORPTION; AQUEOUS SOLUTION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CYCLIZATION; DRUG DOSAGE FORM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE;

ABSORPTION; AMINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EXCIPIENTS; FORMALDEHYDE; MEGLUMINE;

EID: 70349682571     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.57.1096     Document Type: Article

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