Novel benzofuran derivatives with dual 5-HT1A receptor and serotonin transporter affinity

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 3, 2010, Pages 824-827

  Venkatesan, Aranapakam M ^a   Dos Santos, O ^a   Ellingboe, John ^a   Evrard, Deborah A ^b   Harrison, Boyd L ^b   Smith, Deborah L ^b   Scerni, Rosemary ^b   Hornby, Geoffrey A ^b   Schechter, Lee E ^b   Andree, Terrence H ^b  

^a WYETH RESEARCH   (United States)

^b PFIZER INC   (United States)

Author keywords

5HT 1A; Benzofuran; SSRI

Indexed keywords

ALKYL GROUP; BENZOFURAN DERIVATIVE; PYRIDINE DERIVATIVE; SEROTONIN 1A RECEPTOR; SEROTONIN TRANSPORTER; BENZOFURAN; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; NONHUMAN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; ANIMAL; CHEMISTRY; CHO CELL LINE; COMPARATIVE STUDY; CRICETULUS; HAMSTER; HUMAN; METABOLISM; PHYSIOLOGY;

ANIMALS; BENZOFURANS; CHO CELLS; CRICETINAE; CRICETULUS; HUMANS; PROTEIN BINDING; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 74049151635     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.093     Document Type: Article

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