Gene polymorphism of IFNG +874 T/A and TLR4 +896 A/G and recurrent infections and wheezing in toddlers with history of bronchiolitis

Pediatric Infectious Disease Journal

Volumn 28, Issue 12, 2009, Pages 1121-1123

  Nuolivirta, Kirsi ^a   Hurme, Mikko ^b   Halkosalo, Anne ^b   Koponen, Petri ^a   Korppi, Matti ^a   Vesikari, Timo ^b   Helminen, Merja ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b UNIVERSITY OF TAMPERE MEDICAL SCHOOL   (Finland)

Author keywords

Bronchiolitis; Cytokine polymorphism; Recurrent; TLR4

Indexed keywords

CORTICOSTEROID; CYTOKINE; TOLL LIKE RECEPTOR 4;

ALLELE; ARTICLE; BRONCHIOLITIS; CHILD; DISEASE PREDISPOSITION; DRUG USE; FEMALE; GENE; GENETIC POLYMORPHISM; HETEROZYGOTE; HUMAN; IFNG GENE; IL10 GENE; IL18 GENE; INFANT; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRESCHOOL CHILD; PRIORITY JOURNAL; RECURRENT INFECTION; TLR4 GENE; TYMPANOSTOMY TUBE; WHEEZING;

EID: 74049147386     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e3181af37ee     Document Type: Article

References (10)

1. Kotaniemi-Syrjanen A, Vainionpaä R, Reijonen T, et al. Rhinovirus-induced wheezing in infancy-the first sign on childhood asthma? J Allergy Clin Immunol. 2003;111:66-71.
2. Helminen M, Nuolivirta K, Virta M, etal. IL-10 gene polymorphism at-1082 A/G is associated with severe rhinovirus bronchiolitis in infants. Pediatr Pulmonol. 2008;43:391-395.
3. Mandelberg A, Tal G, Naugolny L, et al. Lipopolysaccharide hyporespon-siveness as a risk factor for intensive care unit hospitalization in infants with respiratory syncycitial virus bronchiolitis. Clin Exp Immunol. 2006;144: 48-52.
4. Kurt-Jones EA, Popova L, Kwinn L, et al. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol. 2000;1:398-401.
5. Pravica V, Perrey C, Stevens A, et al. A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production. Hum Immunol. 2000;61:863-866.
6. Asderakis A, Sankaran D, Dyer P, et al. Association of polymorphisms in the human interferon-gamma and interleukin-10 gene with acute and chronic kidney transplant outcome: the cytokine effect on transplantation. Transplantation. 2001;71:674-677.
7. Cabantous S, Poudiougou B, Traore A, et al. Evidence that interferon-gamma plays a protective role during cerebral malaria. J Infect Dis. 2005;192:854-860.
8. King JK, Yeh SH, Lin MW, et al. Genetic polymorphisms in interferon pathway and response to interferon treatment in hepatitis B patients: a pilot study. Hepatology. 2002;36:1416-1424.
9. Bowerfind WML, Fryer AD, Jacoby DB. Double-stranded RNA causes airway hyperreactivity and neuronal M2 muscarinic receptor dysfunction. J Appl Physiol. 2002;92:1417-1422.
10. Lorenz E, Mira JP, Frees KL, et al. Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch Intern Med. 2002;162:1028-1032