메뉴 건너뛰기




Volumn 84, Issue 2, 2010, Pages 109-116

IGHV3-21 gene usage is associated with high TCL1 expression in chronic lymphocytic leukemia

Author keywords

Chronic lymphocytic leukemia; IGHV gene mutational status; IGHV3 21 gene usage; Prognosis; TCL1 expression

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; MESSENGER RNA; MUTANT PROTEIN; REGULATOR PROTEIN; T CELL LEUKEMIA LYMPHOMA PROTEIN 1; UNCLASSIFIED DRUG;

EID: 74049137481     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2009.01369.x     Document Type: Article
Times cited : (7)

References (28)
  • 1
    • 0033567968 scopus 로고    scopus 로고
    • Ig v gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle RN, Wasil T, Fais F, et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 1999 94 : 1840 1847.
    • (1999) Blood , vol.94 , pp. 1840-1847
    • Damle, R.N.1    Wasil, T.2    Fais, F.3
  • 2
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999 94 : 1848 1854.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 3
    • 0037103212 scopus 로고    scopus 로고
    • H mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia
    • Krober A, Seiler T, Benner A, Bullinger L, Bruckle E, Lichter P, Dohner H, Stilgenbauer S. V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia. Blood 2002 100 : 1410 1416. (Pubitemid 34864299)
    • (2002) Blood , vol.100 , Issue.4 , pp. 1410-1416
    • Krober, A.1    Seiler, T.2    Benner, A.3    Bullinger, L.4    Bruckle, E.5    Lichter, P.6    Dohner, H.7    Stilgenbauer, S.8
  • 4
    • 0037103257 scopus 로고    scopus 로고
    • Multivariate analysis of prognostic factors in CLL: Clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors
    • Oscier DG, Gardiner AC, Mould SJ, et al. Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors. Blood 2002 100 : 1177 1184.
    • (2002) Blood , vol.100 , pp. 1177-1184
    • Oscier, D.G.1    Gardiner, A.C.2    Mould, S.J.3
  • 5
    • 10744230550 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: Implicating recognition of a common antigen epitope
    • Tobin G, Thunberg U, Johnson A, et al. Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope. Blood 2003 101 : 4952 4957.
    • (2003) Blood , vol.101 , pp. 4952-4957
    • Tobin, G.1    Thunberg, U.2    Johnson, A.3
  • 6
    • 33645507226 scopus 로고    scopus 로고
    • Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status
    • Thorselius M, Krober A, Murray F, et al. Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status. Blood 2006 107 : 2889 2894.
    • (2006) Blood , vol.107 , pp. 2889-2894
    • Thorselius, M.1    Krober, A.2    Murray, F.3
  • 7
    • 46749099871 scopus 로고    scopus 로고
    • Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection
    • Ghia EM, Jain S, Widhopf GF II., et al. Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection. Blood 2008 111 : 5101 5108.
    • (2008) Blood , vol.111 , pp. 5101-5108
    • Ghia, E.M.1    Jain, S.2    Widhopf, II.G.F.3
  • 8
    • 13544275555 scopus 로고    scopus 로고
    • Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: The lesson of the IGHV3-21 gene
    • Ghia P, Stamatopoulos K, Belessi C, et al. Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: the lesson of the IGHV3-21 gene. Blood 2005 105 : 1678 1685.
    • (2005) Blood , vol.105 , pp. 1678-1685
    • Ghia, P.1    Stamatopoulos, K.2    Belessi, C.3
  • 9
    • 33846108722 scopus 로고    scopus 로고
    • Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations
    • Stamatopoulos K, Belessi C, Moreno C, et al. Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: pathogenetic implications and clinical correlations. Blood 2007 109 : 259 270.
    • (2007) Blood , vol.109 , pp. 259-270
    • Stamatopoulos, K.1    Belessi, C.2    Moreno, C.3
  • 12
    • 0033636528 scopus 로고    scopus 로고
    • The protooncogene TCL1 is an Akt kinase coactivator
    • Laine J, Kunstle G, Obata T, Sha M, Noguchi M. The protooncogene TCL1 is an Akt kinase coactivator. Mol Cell 2000 6 : 395 407.
    • (2000) Mol Cell , vol.6 , pp. 395-407
    • Laine, J.1    Kunstle, G.2    Obata, T.3    Sha, M.4    Noguchi, M.5
  • 13
    • 34347344996 scopus 로고    scopus 로고
    • TCL1 in B-cell tumors retains its normal b-cell pattern of regulation and is a marker of differentiation stage
    • Herling M, Patel KA, Hsi ED, Chang KC, Rassidakis GZ, Ford R, Jones D. TCL1 in B-cell tumors retains its normal b-cell pattern of regulation and is a marker of differentiation stage. Am J Surg Pathol 2007 31 : 1123 1129.
    • (2007) Am J Surg Pathol , vol.31 , pp. 1123-1129
    • Herling, M.1    Patel, K.A.2    Hsi, E.D.3    Chang, K.C.4    Rassidakis, G.Z.5    Ford, R.6    Jones, D.7
  • 14
    • 18244384760 scopus 로고    scopus 로고
    • Expression of TCL1 in hematologic disorders
    • Roos J, Hennig I, Schwaller J, et al. Expression of TCL1 in hematologic disorders. Pathobiology 2001 69 : 59 66.
    • (2001) Pathobiology , vol.69 , pp. 59-66
    • Roos, J.1    Hennig, I.2    Schwaller, J.3
  • 15
    • 31444446831 scopus 로고    scopus 로고
    • TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state
    • Herling M, Patel KA, Khalili J, Schlette E, Kobayashi R, Medeiros LJ, Jones D. TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state. Leukemia 2006 20 : 280 285.
    • (2006) Leukemia , vol.20 , pp. 280-285
    • Herling, M.1    Patel, K.A.2    Khalili, J.3    Schlette, E.4    Kobayashi, R.5    Medeiros, L.J.6    Jones, D.7
  • 16
    • 35748953775 scopus 로고    scopus 로고
    • Expression of TCL-1 as a potential prognostic factor for treatment outcome in B-cell chronic lymphocytic leukemia
    • Browning RL, Geyer SM, Johnson AJ, et al. Expression of TCL-1 as a potential prognostic factor for treatment outcome in B-cell chronic lymphocytic leukemia. Leuk Res 2007 31 : 1737 1740.
    • (2007) Leuk Res , vol.31 , pp. 1737-1740
    • Browning, R.L.1    Geyer, S.M.2    Johnson, A.J.3
  • 17
    • 74049142946 scopus 로고    scopus 로고
    • High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia
    • Epub ahead of print X.J.*Albesiano E.*Zanesi N.*Yancopoulos S.*Sawyer A.*Romano E.*Petlickovski A.*Efremov D.G.*Croce C.M.*Chiorazzi N.
    • Herling M, Patel KA, Weit N, Lilienthal N, Hallek M, Keating MJ, Jones D. High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia. Blood 2009 Epub ahead of print XJ, Albesiano E, Zanesi N, Yancopoulos S, Sawyer A, Romano E, Petlickovski A, Efremov DG, Croce CM, Chiorazzi N. B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2006 103 : 11713 11718.
    • (2009) Blood , vol.103 , pp. 11713-11718
    • Herling, M.1    Patel, K.A.2    Weit, N.3    Lilienthal, N.4    Hallek, M.5    Keating, M.J.6    Jones, D.7
  • 18
    • 59149093632 scopus 로고    scopus 로고
    • TCL1A expression delineates biological and clinical variability in B-cell lymphoma
    • Aggarwal M, Villuendas R, Gomez G, et al. TCL1A expression delineates biological and clinical variability in B-cell lymphoma. Mod Pathol 2009 22 : 206 215.
    • (2009) Mod Pathol , vol.22 , pp. 206-215
    • Aggarwal, M.1    Villuendas, R.2    Gomez, G.3
  • 20
    • 0032887466 scopus 로고    scopus 로고
    • Clonal rearrangements in childhood and adult precursor B acute lymphoblastic leukemia: A comparative polymerase chain reaction study using multiple sets of primers
    • Li AH, Rosenquist R, Forestier E, Holmberg D, Lindh J, Lofvenberg E, Roos G. Clonal rearrangements in childhood and adult precursor B acute lymphoblastic leukemia: a comparative polymerase chain reaction study using multiple sets of primers. Eur J Haematol 1999 63 : 211 218.
    • (1999) Eur J Haematol , vol.63 , pp. 211-218
    • Li, A.H.1    Rosenquist, R.2    Forestier, E.3    Holmberg, D.4    Lindh, J.5    Lofvenberg, E.6    Roos, G.7
  • 21
    • 3242876679 scopus 로고    scopus 로고
    • IMGT/V-QUEST, an integrated software program for immunoglobulin and T cell receptor V-J and V-D-J rearrangement analysis
    • (Web Server issue)
    • Giudicelli V, Chaume D, Lefranc MP. IMGT/V-QUEST, an integrated software program for immunoglobulin and T cell receptor V-J and V-D-J rearrangement analysis. Nucleic Acids Res 2004 32 (Web Server issue) : W435 40.
    • (2004) Nucleic Acids Res , vol.32 , pp. 435-40
    • Giudicelli, V.1    Chaume, D.2    Lefranc, M.P.3
  • 24
    • 33846190181 scopus 로고    scopus 로고
    • Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181
    • Pekarsky Y, Santanam U, Cimmino A, et al. Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res 2006 66 : 11590 11593.
    • (2006) Cancer Res , vol.66 , pp. 11590-11593
    • Pekarsky, Y.1    Santanam, U.2    Cimmino, A.3
  • 27
    • 39649124274 scopus 로고    scopus 로고
    • The TCL1 oncoprotein inhibits activation-induced cell death by impairing PKCtheta and ERK pathways
    • Despouy G, Joiner M, Le Toriellec E, Weil R, Stern MH. The TCL1 oncoprotein inhibits activation-induced cell death by impairing PKCtheta and ERK pathways. Blood 2007 110 : 4406 4416.
    • (2007) Blood , vol.110 , pp. 4406-4416
    • Despouy, G.1    Joiner, M.2    Le Toriellec, E.3    Weil, R.4    Stern, M.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.