Angiotensin II stimulates trafficking of NHE3, NaPi2, and associated proteins into the proximal tubule microvilli

American Journal of Physiology - Renal Physiology

Volumn 298, Issue 1, 2010, Pages

  Riquier Brison, Anne D M ^a   Leong, Patrick K K ^a   Pihakaski Maunsbach, Kaarina ^b   McDonough, Alicia A ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Captopril; Hypertension

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANGIOTENSIN II; CAPTOPRIL; CLATHRIN; EZRIN; MEGALIN; MICROSOMAL AMINOPEPTIDASE; MYOSIN VI; SODIUM CHLORIDE; SODIUM PHOSPHATE COTRANSPORTER 2; SODIUM PROTON EXCHANGE PROTEIN 3; CYTOSKELETON PROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; MYOSIN HEAVY CHAIN; SODIUM PROTON EXCHANGE PROTEIN; SODIUM-HYDROGEN EXCHANGER 3;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CELL MIGRATION; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM VESICLE; DENSITY GRADIENT; KIDNEY PROXIMAL TUBULE; MICROVILLUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; URINE VOLUME; ANIMAL; ANIMAL MODEL; BLOOD PRESSURE; DRUG EFFECT; GLOMERULUS FILTRATION RATE; MALE; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BLOOD PRESSURE; CAPTOPRIL; CLATHRIN; CYTOSKELETAL PROTEINS; GLOMERULAR FILTRATION RATE; KIDNEY TUBULES, PROXIMAL; LDL-RECEPTOR RELATED PROTEIN 2; MALE; MICROVILLI; MODELS, ANIMAL; MYOSIN HEAVY CHAINS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHLORIDE; SODIUM-HYDROGEN ANTIPORTER; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS, TYPE II;

EID: 74049118932     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00464.2009     Document Type: Article

References (47)

1. Ardaillou R. Active fragments of angiotensin II: enzymatic pathways of synthesis and biological effects. Curr Opin Nephrol Hypertens 6: 28-34, 1997.
2. Arrondel C, Vodovar N, Knebelmann B, Grunfeld JP, Gubler MC, Antignac C, Heidet L. Expression of the nonmuscle myosin heavy chain IIA in the human kidney and screening for MYH9 mutations in Epstein and Fechtner syndromes. J Am Soc Nephrol 13: 65-74, 2002.
3. + exchanger isoform NHE3 in the proximal tubule. J Biol Chem 274: 17518-17524, 1999.
4. Braam B, Allen P, Benes E, Koomans HA, Navar LG, Hammond T. Human proximal tubular cell responses to angiotensin II analyzed using DNA microarray. Eur J Pharmacol 464: 87-94, 2003.
5. Brown D, Hirsch S, Gluck S. Localization of a proton-pumping ATPase in rat kidney. J Clin Invest 82: 2114-2126, 1988.
6. Cogan MG. Angiotensin II: a powerful controller of sodium transport in the early proximal tubule. Hypertension 15: 451-458, 1990.
7. Crowley SD, Gurley SB, Herrera MJ, Ruiz P, Griffiths R, Kumar AP, Kim HS, Smithies O, Le TH, Coffman TM. Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. Proc Natl Acad Sci USA 103: 17985-17990, 2006.
8. Donowitz M, Li X. Regulatory binding partners and complexes of NHE3. Physiol Rev 87: 825-872, 2007.
9. Du Cheyron D, Chalumeau C, Defontaine N, Klein C, Kellermann O, Paillard M, Poggioli J. Angiotensin II stimulates NHE3 activity by exocytic insertion of the transporter: role of PI 3-kinase. Kidney Int 64: 939-949, 2003.
10. - cotransport in the rabbit proximal tubule. Proc Natl Acad Sci USA 87: 7917-7920, 1990.
11. + exchanger isoform NHE3 in proximal tubule cells. Am J Physiol Cell Physiol 287: C1238-C1245, 2004.
12. Gurley SB, Parsons KK, Haase VH, Snouwaert JN, Koller BH, Thu HL, Coffman TC. Attenuated salt sensitivity in mice with tissue-specific deletion of AT1A angiotensin receptors from renal proximal tubule. Hypertension 50: e99, 2007.
13. Harris PJ, Navar LG, Ploth DW. Evidence for angiotensin-stimulated proximal tubular fluid reabsorption in normotensive and hypertensive rats: effect of acute administration of captopril. Clin Sci (Lond) 66: 541-544, 1984.
14. Kobori H, Nangaku M, Navar LG, Nishiyama A. The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev 59: 251-287, 2007.
15. + exchanger NHE3 at PKA consensus sites. Am J Physiol Renal Physiol 289: F249-F258, 2005.
16. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
17. Leong PK, Devillez A, Sandberg MB, Yang LE, Yip DK, Klein JB, McDonough AA. Effects of ACE inhibition on proximal tubule sodium transport. Am J Physiol Renal Physiol 290: F854-F863, 2006.
18. + transporter redistribution patterns. Am J Physiol Regul Integr Comp Physiol 287: R878-R885, 2004.
19. Leong PK, Zhang Y, Yang LE, Holstein-Rathlou NH, McDonough AA. Diuretic response to acute hypertension is blunted during angiotensin II clamp. Am J Physiol Regul Integr Comp Physiol 283: R837-R842, 2002.
20. Lorenz JN, Schultheis PJ, Traynor T, Shull GE, Schnermann J. Micropuncture analysis of single-nephron function in NHE3-deficient mice. Am J Physiol Renal Physiol 277: F447-F453, 1999.
21. Mahon MJ. Ezrin promotes functional expression and parathyroid hormonemediated regulation of the sodium-phosphate cotransporter 2a in LLC-PK1 cells. Am J Physiol Renal Physiol 294: F667-F675, 2008.
22. Maunsbach AB. The influence of different fixatives and fixation methods on the ultrastructure of rat kidney proximal tubule cells. I. Comparison of different perfusion fixation methods and of glutaraldehyde, formaldehyde and osmium tetroxide fixatives. J Ultrastruct Res 15: 242-282, 1966.
23. Mitchell KD, Braam B, Navar LG. Hypertensinogenic mechanisms mediated by renal actions of renin-angiotensin system. Hypertension 19: I18-I27, 1992.
24. Murer H, Hernando N, Forster L, Biber J. Molecular mechanisms in proximal tubular and small intestinal phosphate reabsorption (plenary lecture). Mol Membr Biol 18: 3-11, 2001.
25. +-ATPase in proton-secreting cells of the kidney and epididymis. Am J Physiol Cell Physiol 287: C149-C162, 2004.
26. + cotransporter (NCC) in response to a high-salt diet. Am J Physiol Renal Physiol 291: F503-F508, 2006.
27. + cotransporter to apical membrane. Am J Physiol Renal Physiol 293: F662-F669, 2007.
28. Sellers JR. Myosins: a diverse superfamily. Biochim Biophys Acta 1496: 3-22, 2000.
29. Shao W, Seth DM, Navar LG. Augmentation of endogenous intrarenal angiotensin II levels in Va15-ANG II-infused rats. Am J Physiol Renal Physiol 296: F1067-F1071, 2009.
30. Shenolikar S, Voltz JW, Minkoff CM, Wade JB, Weinman EJ. Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wasting. Proc Natl Acad Sci USA 99: 11470-11475, 2002.
31. Thomson SC, Deng A, Wead L, Richter K, Blantz RC, Vallon V. An unexpected role for angiotensin II in the link between dietary salt and proximal reabsorption. J Clin Invest 116: 1110-1116, 2006.
32. Traebert M, Roth J, Biber J, Murer H, Kaissling B. Internalization of proximal tubular type II Na-Pi cotransporter by PTH: immunogold electron microscopy. Am J Physiol Renal Physiol 278: F148-F154, 2000.
33. Turban S, Beutler KT, Morris RG, Masilamani S, Fenton RA, Knepper MA, Packer RK. Long-term regulation of proximal tubule acid-base transporter abundance by angiotensin II. Kidney Int 70: 660-668, 2006.
34. Voltz JW, Brush M, Sikes S, Steplock D, Weinman EJ, Shenolikar S. Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets. J Biol Chem 282: 33879-33887, 2007.
35. Weinman EJ, Boddeti A, Cunningham R, Akom M, Wang F, Wang Y, Liu J, Steplock D, Shenolikar S, Wade JB. NHERF-1 is required for renal adaptation to a low-phosphate diet. Am J Physiol Renal Physiol 285: F1225-F1232, 2003.
36. Weinman EJ, Cunningham R, Wade JB, Shenolikar S. The role of NHERF-1 in the regulation of renal proximal tubule sodium-hydrogen exchanger 3 and sodium-dependent phosphate cotransporter 2a. J Physiol 567: 27-32, 2005.
37. Weir MR, Dzau VJ. The renin-angiotensin-aldosterone system: a specific target for hypertension management. Am J Hypertens 12: 205S-213S, 1999.
38. Xu L, Dixit MP, Chen R, Dixit NM, Collins JF, Ghishan FK. Effects of angiotensin II on NaPi-IIa cotransporter expression and activity in rat renal cortex. Biochim Biophys Acta 1667: 114-121, 2004.
39. Yang L, Leong PK, Chen JO, Patel N, Hamm-Alvarez SF, McDonough AA. Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity. Am J Physiol Renal Physiol 282: F730-F740, 2002.
40. Yang LE, Leong PK, McDonough AA. Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance. Am J Physiol Renal Physiol 293: F1197-F1208, 2007.
41. + transporters during hypertension or PTH: NHE3 to base of microvilli vs. NaPi2 to endosomes. Am J Physiol Renal Physiol 287: F896-F906, 2004.
42. Yang LE, Maunsbach AB, Leong PK, McDonough AA. Redistribution of myosin VI from top to base of proximal tubule microvilli during acute hypertension. J Am Soc Nephrol 16: 2890-2896, 2005.
43. + transporters' subcellular distribution, abundance, and phosphorylation status. Am J Physiol Renal Physiol In press.
44. Zhang Y, Magyar CE, Norian JM, Holstein-Rathlou NH, Mircheff AK, McDonough AA. Reversible effects of acute hypertension on proximal tubule sodium transporters. Am J Physiol Cell Physiol 274: C1090-C1100, 1998.
45. Zhang Y, Mircheff AK, Hensley CB, Magyar CE, Warnock DG, Chambrey R, Yip KP, Marsh DJ, Holstein-Rathlou NH, McDonough AA. Rapid redistribution and inhibition of renal sodium transporters during acute pressure natriuresis. Am J Physiol Renal Fluid Electrolyte Physiol 270: F1004-F1014, 1996.
46. Zhang Y, Norian JM, Magyar CE, Holstein-Rathlou NH, Mircheff AK, McDonough AA. In vivo PTH provokes apical NHE3 and NaPi2 redistribution and Na-K-ATPase inhibition. Am J Physiol Renal Physiol 276: F711-F719, 1999.
47. Zhou Y, Boron WF. Role of endogenously secreted angiotensin II in the CO2-induced stimulation of HCO3 reabsorption by renal proximal tubules. Am J Physiol Renal Physiol 294: F245-F252, 2008.