Cellular immunology of sequential dengue virus infection and its role in disease pathogenesis

Current Topics in Microbiology and Immunology

Volumn 338, Issue 1, 2009, Pages 83-98

  Rothman, Alan L ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DENGUE VACCINE; GAMMA INTERFERON; GLUCOCORTICOID; HLA ANTIGEN; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 5; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; EPITOPE;

CELLULAR IMMUNITY; CYTOKINE PRODUCTION; DENGUE; DENGUE VIRUS; DISEASE ASSOCIATION; DISEASE MODEL; DISEASE SEVERITY; DRUG MEGADOSE; ENZYME LINKED IMMUNOSPOT ASSAY; FLOW CYTOMETRY; FUNDING; GENETIC DATABASE; HUMAN; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; IMMUNOSURVEILLANCE; NONHUMAN; POPULATION RESEARCH; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; RISK FACTOR; SECONDARY INFECTION; SHOCK; T LYMPHOCYTE; VACCINATION; ANIMAL; BIOSYNTHESIS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY;

ANIMALIA; DENGUE VIRUS;

ANIMALS; CYTOKINES; DENGUE; DISEASE MODELS, ANIMAL; EPITOPES, T-LYMPHOCYTE; HUMANS; IMMUNOLOGIC MEMORY; T-LYMPHOCYTES;

EID: 74049116296     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-02215-9-7     Document Type: Review

References (47)

1. Altman JD, Moss PA, Goulder PJ, Barouch DH, McHeyzer-Williams MG, Bell JI, McMichael AJ, Davis MM (1996) Phenotypic analysis of antigen-specific Tlymphocytes. Science 274:94-96
2. Askonas BA, Taylor PM, Esquivel F (1988) Cytotoxic T cells in influenza infection. Ann N Y Acad Sci 532:230-237 (Pubitemid 19017643)
3. Bashyam HS, Green S, Rothman AL (2006) Dengue virus-reactive CD8+ T cells display quantitative and qualitative differences in their response to variant epitopes of heterologous viral serotypes. J Immunol 176:2817-2824 (Pubitemid 43306941)
4. Beaumier CM, Mathew A, Bashyam HS, Rothman AL (2008) Cross-reactive memory CD8(+) T cells alter the immune response to heterologous secondary dengue virus infections in mice in a sequence-specific manner. J Infect Dis 197:608-617 (Pubitemid 351321540)
5. Catalina MD, Sullivan JL, Brody RM, LuzuriagaK(2002) Phenotypic and functional heterogeneity of EBV epitope-specific CD8+ T cells. J Immunol 168:4184-4191 (Pubitemid 34298427)
6. Chen L, Ewing D, Subramanian H, Block K, Rayner J, Alterson KD, Sedegah M, Hayes C, Porter K, Raviprakash K (2007) A heterologous DNA prime-Venezuelan equine encephalitis virus replicon particle boost dengue vaccine regimen affords complete protection from virus challenge in cynomolgus macaques. J Virol 81:11634-11639 (Pubitemid 47623795)
7. Dong T, Moran E, Vinh Chau N, Simmons C, Luhn K, Peng Y, Wills B, Phuong Dung N, Thi Thu Thao L, Hien TT, McMichael A, Farrar J, Rowland-Jones S (2007) High pro-inflammatory cytokine secretion and loss of high avidity cross-reactive cytotoxic T-cells during the course of secondary dengue virus infection. PLoS ONE 2:e1192 (Pubitemid 351663849)
8. Endy TP, Chunsuttiwat S, Nisalak A, Libraty DH, Green S, Rothman AL, Vaughn DW, Ennis FA (2002a) Epidemiology of inapparent and symptomatic acute dengue virus infection: a prospective study of primary school children in Kamphaeng Phet, Thailand. Am J Epidemiol 156:40-51 (Pubitemid 34680622)
9. Endy TP, Nisalak A, Chunsuttiwat S, Libraty DH, Green S, Rothman AL, Vaughn DW, Ennis FA (2002b) Spatial and temporal circulation of dengue virus serotypes: a prospective study of primary school children in Kamphaeng Phet, Thailand. Am J Epidemiol 156:52-59 (Pubitemid 34680623)
10. Gagnon SJ, Leporati A, Green S, Kalayanarooj S, Vaughn DW, Stephens HA, Suntayakorn S, Kurane I, Ennis FA, Rothman AL (2001) T cell receptor Vbeta gene usage in Thai children with dengue virus infection. Am J Trop Med Hyg 64:41-48 (Pubitemid 32550097)
11. Green S, Pichyangkul S, Vaughn DW, Kalayanarooj S, Nimmannitya S, Nisalak A, Kurane I, Rothman AL, Ennis FA (1999a) Early CD69 expression on peripheral blood lymphocytes from children with dengue hemorrhagic fever. J Infect Dis 180:1429-1435 (Pubitemid 29506442)
12. Green S, VaughnDW, Kalayanarooj S, Nimmannitya S, Suntayakorn S, Nisalak A, Lew R, Innis BL, Kurane I, Rothman AL, Ennis FA (1999b) Early immune activation in acute dengue is related to development of plasma leakage and disease severity. J Infect Dis 179:755-762 (Pubitemid 29159319)
13. Guy B,Nougarede N, Begue S, Sanchez V, Souag N, Carre M, Chambonneau L,MorrissonDN, Shaw D, Qiao M, Dumas R, Lang J, Forrat R (2008) Cell-mediated immunity induced by chimeric tetravalent dengue vaccine in naive or flavivirus-primed subjects. Vaccine 26:5712-5721
14. Gwinn W, Sun W, Innis BL, Caudill J, King AD (2003) Serotype-specific T(H)1 responses in recipients of two doses of candidate live-attenuated dengue virus vaccines. Am J Trop Med Hyg 69:39-47
15. Halstead SB (1989) Antibody, macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade. Rev Infect Dis 11:S830-S839
16. Hammond SN, Balmaseda A, Perez L, Tellez Y, Saborio SI, Mercado JC, Videa E, Rodriguez Y, Perez MA, Cuadra R, Solano S, Rocha J, Idiaquez W, Gonzalez A, Harris E (2005) Differences in dengue severity in infants, children, and adults in a 3-year hospital-based study in Nicaragua. Am J Trop Med Hyg 73:1063-1070 (Pubitemid 43038255)
17. Hober D, Delannoy AS, Benyoucef S, De Groote D, Wattre P (1996) High levels of sTNFR p75 and TNF alpha in dengue-infected patients. Microbiol Immunol 40:569-573 (Pubitemid 26282110)
18. Hober D, Poli L, Roblin B, Gestas P, Chungue E, Granic G, Imbert P, Pecarere JL, Vergez-Pascal R, Wattre P, Maniez-Montreuil M (1993) Serum levels of tumor necrosis factor-a (TNF-a), interleukin-6 (IL-6), and interleukin-1b (IL-1b) in dengue-infected patients. Am J Trop Med Hyg 48:324-331 (Pubitemid 23115317)
19. Imrie A, Meeks J, Gurary A, Sukhbataar M, Kitsutani P, Effler P, Zhao Z (2007) Differential functional avidity of dengue virus-specific T-cell clones for variant peptides representing heterologous and previously encountered serotypes. J Virol 81:10081-10091 (Pubitemid 350067712)
20. Kalayanarooj S, Vaughn DW, Nimmannitya S, Green S, Suntayakorn S, Kunentrasai N, Viramitrachai W, Ratanachu-eke S, Kiatpolpoj S, Innis BL, Rothman AL, Nisalak A, Ennis FA (1997) Early clinical and laboratory indicators of acute dengue illness. J Infect Dis 176:313-321 (Pubitemid 27328752)
21. Koraka P, Benton S, van Amerongen G, Stittelaar KJ, Osterhaus AD (2007) Efficacy of a live attenuated tetravalent candidate dengue vaccine in naive and previously infected cynomolgus macaques. Vaccine 25:5409-5416 (Pubitemid 46977528)
22. Kurane I, Ennis FA (1992) Immunity and immunopathology in dengue virus infections. Sem Immunol 4:121-127
23. Kurane I, Innis BL, Nimmannitya S, Nisalak A, Meager A, Janus J, Ennis FA (1991) Activation of T lymphocytes in dengue virus infections. High levels of soluble interleukin 2 receptor, soluble CD4, soluble CD8, interleukin 2, and interferon-gamma in sera of children with dengue. J Clin Invest 88:1473-1480
24. Kurane I, Innis BL, Nisalak A, Hoke C, Nimmannitya S, Meager A, Ennis FA (1989a) Human T cell responses to dengue virus antigens. Proliferative responses and interferon gamma production. J Clin Invest 83:506-513 (Pubitemid 19061171)
25. Kurane I, Meager A, Ennis FA (1989b) Dengue virus-specific human T cell clones. Serotype crossreactive proliferation, interferon gamma production, and cytotoxic activity. J Exp Med 170:763-775 (Pubitemid 19226663)
26. Kurane I, Okamoto Y, Dai LC, Zeng LL, Brinton MA, Ennis FA (1995) Flavivirus-cross-reactive, HLA-DR15-restricted epitope on NS3 recognized by human CD4+ CD8-cytotoxic T lymphocyte clones. J Gen Virol 76:2243-2249
27. Lechner F, Wong DK, Dunbar PR, Chapman R, Chung RT, Dohrenwend P, Robbins G, Phillips R, Klenerman P, Walker BD (2000) Analysis of successful immune responses in persons infected with hepatitis C virus. J Exp Med 191:1499-1512 (Pubitemid 30257347)
28. Livingston PG, Kurane I, Dai LC, Okamoto Y, Lai CJ, Men R, Karaki S, Takiguchi M, Ennis FA (1995) Dengue virus-specific, HLA-B35-restricted, human CD8+ cytotoxic T lymphocyte (CTL) clones. Recognition of NS3 amino acids 500 to 508 by CTL clones of two different serotype specificities. J Immunol 154:1287-1295
29. Loke H, Bethell DB, Phuong CX, Dung M, Schneider J, White NJ, Day NP, Farrar J, Hill AV (2001) Strong HLA class I-restricted T cell responses in dengue hemorrhagic fever: a doubleedged sword? J Infect Dis 184:1369-1373 (Pubitemid 33108849)
30. Mangada MM, Endy TP, Nisalak A, Chunsuttiwat S, Vaughn DW, Libraty DH, Green S, Ennis FA, Rothman AL (2002) Dengue-specific T cell responses in peripheral blood mononuclear cells obtained prior to secondary dengue virus infections in Thai schoolchildren. J Infect Dis 185:1697-1703 (Pubitemid 34615461)
31. Mangada MM, Rothman AL (2005) Altered cytokine responses of dengue-specific CD4+ T cells to heterologous serotypes. J Immunol 175:2676-2683
32. Mathew A, Kurane I, Rothman AL, Zeng LL, Brinton MA, Ennis FA (1996) Dominant recognition by human CD8+ cytotoxic T lymphocytes of dengue virus nonstructural proteins NS3 and NS1.2a. J Clin Invest 98:1684-1694 (Pubitemid 26327880)
33. Mongkolsapaya J, Dejnirattisai W, Xu X, Vasanawathana S, Tangthawornchaikul N, Chairunsri A, Sawasdivorn S, Duangchinda T, Dong T, Rowland-Jones S, Yenchitsomanus P, McMichael A, Malasit P, Screaton G (2003) Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nature Med 9(7):921-927 (Pubitemid 36889936)
34. Mongkolsapaya J, Duangchinda T, Dejnirattisai W, Vasanawathana S, Avirutnan P, Jairungsri A, Khemnu N, Tangthawornchaikul N, Chotiyarnwong P, Sae-Jang K, Koch M, Jones Y, McMichael A, Xu X, Malasit P, Screaton G (2006) T cell responses in dengue hemorrhagic fever: are cross-reactive T cells suboptimal? J Immunol 176:3821-3829 (Pubitemid 43364031)
35. Murali-Krishna K, Altman JD, Suresh M, Sourdive DJ, Zajac AJ, Miller JD, Slansky J, Ahmed R (1998) Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity 8:177-187 (Pubitemid 28123745)
36. Panpanich R, Sornchai P, Kanjanaratanakorn K (2006) Corticosteroids for treating dengue shock syndrome. Cochrane Database Syst Rev 3:CD003488
37. Rabablert J, Dharakul T, Yoksan S, Bhamarapravati N (2000) Dengue virus specific T cell responses to live attenuated monovalent dengue-2 and tetravalent dengue vaccines. Asian Pac J Allergy Immunol 18:227-235 (Pubitemid 32249032)
38. Rothman AL, Kanesa-thasan N, West K, Janus J, Saluzzo J, Ennis FA (2001) Induction of T lymphocyte responses to dengue virus by a candidate tetravalent live attenuated dengue virus vaccine. Vaccine 19:4694-4699 (Pubitemid 32800752)
39. Simmons CP, Dong T, Chau NV, Dung NT, Chau TN, Thao-le TT, Hien TT, Rowland-Jones S, Farrar J (2005) Early T-cell responses to dengue virus epitopes in Vietnamese adults with secondary dengue virus infections. J Virol 79:5665-5675 (Pubitemid 40548235)
40. Stephens HA, Klaythong R, Sirikong M, Vaughn DW, Green S, Kalayanarooj S, Endy TP, Libraty DH, Nisalak A, Innis BL, Rothman AL, Ennis FA, Chandanayingyong D (2002) HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais. Tissue Antigens 60:309-318 (Pubitemid 36020803)
41. Tan LC, Gudgeon N, Annels NE, Hansasuta P, OCallaghan CA, Rowland-Jones S, McMichael AJ, Rickinson AB, Callan MF (1999) A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers. J Immunol 162:1827-1835 (Pubitemid 29307064)
42. Tassniyom S, Vasanawathana S, Chirawatkul A, Rojanasuphot S (1993) Failure of high-dose methylprednisolone in established dengue shock syndrome: a placebo-controlled, double-blind study. Pediatrics 92:111-115 (Pubitemid 23188877)
43. Vaughn DW, Green S, Kalayanarooj S, Innis BL, Nimmannitya S, Suntayakorn S, Rothman AL, Ennis FA, Nisalak A (1997) Dengue in the early febrile phase: viremia and antibody responses. J Infect Dis 176:322-330 (Pubitemid 27328753)
44. Wills BA, Oragui EE, Stephens AC, Daramola OA, Dung NM, Loan HT, Chau NV, Chambers M, Stepniewska K, Farrar JJ, Levin M (2002) Coagulation abnormalities in dengue hemorrhagic fever: serial investigations in 167 Vietnamese children with Dengue shock syndrome. Clin Infect Dis 35:277-285 (Pubitemid 34800275)
45. Zhou H, Deem MW (2006) Sculpting the immunological response to dengue fever by polytopic vaccination. Vaccine 24:2451-2459 (Pubitemid 43292511)
46. Zivna I, Green S, Vaughn DW, Kalayanarooj SH, Stephens AF, Chandanayingyong D, Nisalak A, Ennis FA, Rothman AL (2002) T cell responses to an HLA B*07-restricted epitope on the dengue NS3 protein correlate with disease severity. J Immunol 168:5959-5965 (Pubitemid 34556187)
47. Zivny J, DeFronzo M, Jarry W, Jameson J, Cruz J, Ennis FA, Rothman AL (1999) Partial agonist effect influences the CTL response to a heterologous dengue virus serotype. J Immunol 163:2754-2760 (Pubitemid 29399202)