Early immune activation in acute dengue illness is related to development of plasma leakage and disease severity

Journal of Infectious Diseases

Volumn 179, Issue 4, 1999, Pages 755-762

  Green, Sharone ^a   Vaughn, David W ^b   Kalayanarooj, Siripen ^d   Nimmannitya, Suchitra ^d   Suntayakorn, Saroj ^d   Nisalak, Ananda ^d   Lew, Robert ^d   Innis, Bruce L ^d   Kurane, Ichiro ^c   Rothman, Alan L ^d   Ennis, Francis A ^d  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; INTERLEUKIN 2 RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR;

ADOLESCENT; ARTICLE; CHILD; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENGUE; DISEASE CLASSIFICATION; DISEASE MARKER; DISEASE SEVERITY; HEMORRHAGIC FEVER; HUMAN; INTERFERON INDUCTION; INTERFERON PRODUCTION; MAJOR CLINICAL STUDY; PATHOGENESIS; PLEURA EFFUSION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ACUTE DISEASE; ADOLESCENT; ANTIGENS, CD; CHILD; CHILD, PRESCHOOL; CYTOKINES; DENGUE; HUMANS; INFANT; PROSPECTIVE STUDIES; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; SERUM ALBUMIN;

EID: 0032900451     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/314680     Document Type: Article

References (47)

1. Monath TP. Dengue: the risk to developed and developing countries. Proc Natl Acad Sci USA 1994;91:2395-400.
2. Halstead SB, Nimmannitya S, Cohen SN. Observations related to pathogenesis of dengue hemorrhagic fever. IV. Relation of disease severity to antibody response and virus recovered. Yale J Biol Med 1970;42:311-28.
3. Halstead SB, O'Rourke EJ. Dengue viruses and mononuclear phagocytes. I. Infection enhancement by non-neutralizing antibody. J Exp Med 1977;146:201-17.
4. Kurane I, Meager A, Ennis FA. Dengue virus specific human T cell clones. Serotype crossreactive proliferation, interferon-γ production, and cytotoxic activity. J Exp Med 1989;170:763-75.
5. + human cytotoxic T lymphocytes. J Virol 1989;63:5086-91.
6. + T-lymphocyte responses in a recipient of an experimental live-attenuated dengue virus type-1 vaccine: bulk culture proliferation, clonal analysis, and precursor frequency determination. J Virol 1993;67:5962-7.
7. + cytotoxic T-lymphocyte clones. J Virol 1996;70:141-7.
8. Kurane I, Ennis FA. Cytokines in dengue virus infections: role of cytokines in the pathogenesis of dengue hemorrhagic fever. Semin Virol 1994;5:443-8.
9. Krakauer T, LeDuc JW, Krakauer H. Serum levels of tumor necrosis factor-alpha, interleukin-1, and interleukin-6 in hemorrhagic fever with renal syndrome. Viral Immunol 1995;8:75-9.
10. + cytotoxic T lymphocytes to epitopes on Sin Nombre virus nucleocapsid protein isolated during acute illness. Virology 1997;238:380-90.
11. Griffin DE, Ward BJ, Esolen LM. Pathogenesis of measles virus infection: a hypothesis for altered immune responses. J Infect Dis 1994; 170(suppl): S24-31.
12. Kurane I. Innis BL, Nimmannitya S, et al. Activation of T lymphocytes in dengue virus infections. High levels of soluble interleukin 2 receptor, soluble CD4, soluble CD8, interleukin 2, and interferon-γ in sera of children with dengue. J Clin Invest 1991;88:1473-80.
13. Vitarana T, de Silva H, Withana N, Gunasekera C. Elevated tumour necrosis factor in dengue fever and dengue haemorrhagic fever. Ceylon Med J 1991;36:63-5.
14. Hober D, Poli L, Roblin B, et al. Serum levels of tumor necrosis factor-α (TNF-α). interleukin-6 (IL-6), and interleukin-1-β (IL-1-β) in dengue-infected patients. Am J Trop Med Hyg 1993;48:324-31.
15. Kuno G, Bailey RE. Cytokine responses to dengue infection among Puerto Rican patients. Mem Inst Oswaldo Cruz 1994;89:179-82.
16. Kalayanarooj S, Nimmannitya S, Lortholary O, Mencia-Heuta JM, Braque P. Immune mediators in dengue and dengue hemorrhagic fever patients. JAMA Southeast Asia 1994; 10(Suppl):400-2.
17. Hober D, Delannoy AS, Benyoucef S, De Groote D, Wattre P. High levels of sTNFR p75 and TNFα in dengue-infected patients. Microbiol Immunol 1996;40:569-73.
18. Bethell DB, Flobbe K, Phuong CXT, et al. Pathophysiologic and prognostic role of cytokines in dengue hemorrhagic fever. J Infect Dis 1998;177:778-82.
19. Kalayanarooj S, Vaughn DW, Nimmannitya S, et al. Early clinical and laboratory indicators of acute dengue illness. J Infect Dis 1997;176:313-21.
20. Dengue haemorrhagic fever: diagnosis, treatment and control Geneva: World Health Organization, 1986.
21. Innis BL, Nisalak A, Nimmannitya S, et al. An enzyme-linked immunosorbent assay to characterize dengue infections where dengue and Japanese encephalitis co-circulate. Am J Trop Med Hyg 1989;40:418-27.
22. Clarke DH, Casals J. Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. Am J Trop Med Hyg 1958;7:561-73.
23. Rosen L, Gubler DJ. The use of mosquitoes to detect and propagate dengue viruses. Am J Trop Med Hyg 1974;23:1153-60.
24. Rosen L. The use of toxorhynchites mosquitoes to detect and propagate dengue and other arboviruses. Am J Trop Med Hyg 1981;30:177-83.
25. Vaughn DW, Green S, Kalayanarooj S, et al. Dengue in the early febrile phase: viremia and antibody responses. J Infect Dis 1997;176:322-30.
26. SAS/STAT user's guide, version 6. 4th ed. Vols 1 and 2. Cary, NC: SAS Institute, 1994.
27. Armitage P. Statistical methods in medical research. New York: Wiley, 1971.
28. Sung SSJ. Bjorndahl JM, Wang CY, Kao HT, Fu SM. Production of tumor necrosis factor/cachectin by human T cell lines and peripheral blood T lymphocytes stimulated by phorbol myristate acetate and anti-CD3 antibody. J Exp Med 1988;167:937-53.
29. Trinchieri G, Perussia B. Immune interferon: a pleiotropic lymphokine with multiple effects. Immunol Today 1985;6:131-6.
30. Bemelmans MHA, Abramowicz D, Gouma DJ, Goldman M, Buurman WA. In vivo T cell activation by anti-CD3 monoclonal antibody induces soluble TNF receptor release in mice. J Immunol 1994;153:499-506.
31. Rubin LA, Kurman CC, Fritz ME, et al. Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro. J Immunol 1985;135:3172-7.
32. Fujimoto J, Levy S, Levy R. Spontaneous release of the leu-2 (T8) molecule from human T cells. J Exp Med 1983;158:752-66.
33. Tomkinson BE, Brown MC, Ip SH, Carrabis S, Sullivan JL. Soluble CD8 during T cell activation. J Immunol 1989;142:2230-6.
34. Kurane I, Innis BL, Nisalak A, et al. Human T cell responses to dengue virus antigens. Proliferative responses and interferon gamma production. J Clin Invest 1989,83:506-13.
35. Stolpen AH, Guinan EC, Fiers W, Pober JS. Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers. Am J Pathol 1986;123:16-24.
36. Burke-Gaffney A, Keenan AK. Modulation of human endothelial cell permeability by combinations of the cytokines interleukin-1 αlβ, tumor necrosis factor-α, and interferon-γ. Immunopharmacology 1993;25:1-9.
37. Pober JS. Cytokine-mediated activation of vascular endothelium. Am J Pathol 1988;133:426-33.
38. Aggarwal BB, Eessalu TE, Hass PE. Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon. Nature 1985;318:665-7.
39. Ruggiero V, Tavernier J, Fiers W, Baglioni C. Induction of the synthesis of tumor necrosis factor receptors by interferon-γ. J Immunol 1986;136: 2445-50.
40. Pandita R, Pocsik E, Aggarwal BB. Interferon-γ induces cell surface expression for both types of tumor necrosis factor receptors. FEBS Lett 1992;312:87-90.
41. Grau GE, Heremans H, Piguet PF, et al. Monoclonal antibody against interferon-γ can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor. Proc Natl Acad Sci USA 1989;86: 5572-4.
42. Heinzel FP. The role of IFN-γ in the pathology of experimental endotoxemia. J Immunol 1990;145:2920-4.
43. Waki S, Uehara S, Kanbe K, Ono K, Suzuki M, Nariuchi H. The role of T cells in pathogenesis and protective immunity to murine malaria. Immunology 1992;75:646-51.
44. Car BD, Eng VM, Schnyder B, et al. Interferon-γ receptor deficient mice are resistant to endotoxic shock. J Exp Med 1994;179:1437-44.
45. Morita K, Maemoto T, Honda S, et al. Rapid detection of virus genome from imported dengue fever and dengue hemorrhagic fever patients by direct polymerase chain reaction. J Med Virol 1994;44:54-8.
46. Seah CLK, Chow VTK, Tan HC, Chan YC. Rapid, single-step RT-PCR typing of dengue viruses using five NS3 gene primers. J Virol Methods 1995;51:193-200.
47. Sudiro TM, Ishiko H, Green S, et al. Rapid diagnosis of dengue viremia by reverse transcriptase polymerase chain reaction using 3′-noncoding region universal primers. Am J Trop Med Hyg 1997;56:424-9.