NMR-solution structures and affinities for the human somatostatin G-protein-coupled receptors hsst 1-5 of CF 3 derivatives of Sandostatin® (octreotide)

Helvetica Chimica Acta

Volumn 92, Issue 12, 2009, Pages 2577-2586

  Seebach, Dieter ^a   Widmer, Hans ^b   Capone, Stefania ^a   Ernst, Richard ^a   Bremi, Tobias ^a   Kieltsch, Iris ^c   Togni, Antonio ^c   Monna, Dominique ^b   Langenegger, Daniel ^b   Hoyer, Daniel ^b  

^a ETH ZURICH   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c LABORATORY OF INORGANIC CHEMISTRY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHAIN COMPOUNDS; CHAIN STRUCTURE; G PROTEIN COUPLED RECEPTORS; MACROCYCLES; NMR ANALYSIS; OCTREOTIDE; SOLUTION STRUCTURES; TIME-SCALES;

TIME MEASUREMENT;

NUCLEAR MAGNETIC RESONANCE;

G PROTEIN COUPLED RECEPTOR; OCTREOTIDE; SOMATOSTATIN RECEPTOR 1; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR 3; SOMATOSTATIN RECEPTOR 4; SOMATOSTATIN RECEPTOR 5;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBON NUCLEAR MAGNETIC RESONANCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; RECEPTOR AFFINITY; RELAXATION TIME;

EID: 74049115116     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200900279     Document Type: Article

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