Treatment practices in adults with chronic immune thrombocytopenia - A European perspective

European Journal of Haematology

Volumn 84, Issue 2, 2010, Pages 160-168

  Rodeghiero, Francesco ^a   Besalduch, Juan ^b   Michel, Marc ^c   Provan, Drew ^d   Grotzinger, Kelly ^e   Thompson, Gwilym ^f  

^a Department of Cellular Therapy and Haematology   (Italy)

^b HOSPITAL UNIVERSITARIO SON ESPASES   (Spain)

^c HENRI MONDOR HOSPITAL   (France)

^d QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^e GLAXOSMITHKLINE   (United States)

^f GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Chronic immune thrombocytopenia; Platelet count; Standard care; Treatment

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DANAZOL; DAPSONE; IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT; PREDNISOLONE; PREDNISONE; RITUXIMAB; TRANEXAMIC ACID; VINCRISTINE;

ARTICLE; BLEEDING; CHRONIC IMMUNE THROMBOCYTOPENIA; CLINICAL DECISION MAKING; CLINICAL PRACTICE; CUSHING SYNDROME; DIABETES MELLITUS; DIABETIC PATIENT; DRUG CHOICE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; EVIDENCE BASED MEDICINE; HIGH RISK PATIENT; HUMAN; HYPERTENSION; IMMUNE DEFICIENCY; KIDNEY FUNCTION; LOW DRUG DOSE; MEDICAL RECORD REVIEW; OSTEOPOROSIS; PHYSICIAN ATTITUDE; PRACTICE GUIDELINE; PREGNANT WOMAN; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SPLENECTOMY; SURGICAL RISK; THROMBOCYTE COUNT; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; TREATMENT DURATION; TREATMENT OUTCOME;

ADRENAL CORTEX HORMONES; ADULT; AGE OF ONSET; AGED; CHRONIC DISEASE; EUROPE; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; MALE; MIDDLE AGED; PLATELET COUNT; PRACTICE GUIDELINES AS TOPIC; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; RETROSPECTIVE STUDIES; SPLENECTOMY;

EID: 74049089002     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2009.01361.x     Document Type: Article

References (39)

1. McMillan R, Durette C. Long-term outcomes in adults with chronic ITP after splenectomy failure. Blood 2004 104 : 956 960.
2. Cines DB, Bussel JB, McMillan RB, Zehnder JL. Congenital and acquired thrombocytopenia. Hematology Am Soc Hematol Educ Program 2004 390 406.
3. Cines DB, Blanchette VS. Immune Thrombocytopenia Purpura. N Engl J Med 2002 346 : 995 1008.
4. Fogarty PF, Segal JB. The epidemiology of immune thrombocytopenic purpura. Curr Opin Hematol 2007 14 : 515 519.
5. George JN. Management of patients with refractory immune thrombocytopenic purpura. J Thromb Haemost 2006 4 : 1664 1672.
6. Rodeghiero F, Stasi R, Gernsheimer T, et al. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenia purpura (ITP) of adults and children: report from an International working party. Blood 2009 113 : 2386 2393.
7. Godeau B, Provan D, Bussel J. Immune thrombocytopenic purpura in adults. Curr Opin Hematol 2007 14 : 535 556.
8. Arnold DM, Kelton JG. Current options for the treatment of idiopathic thrombocytopenic purpura. Semin Hematol 2007 4 (Suppl. 5 S12 23.
9. Cines DB, Bussel JB. How I treat idiopathic thrombocytopenic purpura (ITP). Blood 2005 106 : 2244 2251.
10. George JN, Woolf SH, Raskob GE, et al. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood 1996 88 : 3 40.
11. Rodeghiero F. Idiopathic thrombocytopenic purpura: an old disease revisited in the era of evidence-based medicine. Haematologica 2003 88 : 1081 1087.
12. British Committee for Standards in Haematology, General Haematology Task Force. Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy. Br J Haematol. 2003 120 : 574 596.
13. Stasi R, Provan D. Management of immune thrombocytopenic purpura in adults. Mayo Clin Proc 2004 79 : 504 522.
14. Stasi R, Stipa E, Masi M, et al. Long-term observation of 208 adults with chronic idiopathic thrombocytopenic purpura. Am J Med 1995 98 : 436 442.
15. Godeau B, Chevret S, Varet B, et al. Intravenous immunoglobulin or high-dose methylprednisolone, with or without oral prednisone, for adults with untreated severe autoimmune thrombocytopenic purpura: a randomised, multicentre trial. Lancet 2002 359 : 23 9.
16. George JN, el-Harake MA, Raskob GE. Chronic idiopathic thrombocytopenic purpura. N Engl J Med 1994 331 : 1207 1211.
17. Ben-Yehuda D, Gillis S, Eldor A. Clinical and therapeutic experience in 712 Israeli patients with idiopathic thrombocytopenic purpura. Acta Haematol 1994 91 : 1 6.
18. Blanchette V, Freedman J, Garvey B. Management of chronic immune thrombocytopenic purpura in children and adults. Semin Hematol 1998 35 : 36 51. (Pubitemid 28136666)
19. Bromberg ME. Immune Thrombocytopenic Purpura- The changing therapeutic landscape. N Engl J Med 2006 355 : 1643 1645.
20. Schwartz J, Leber MD, Gillis S, Giunta A, Eldor A, Bussel JB. Long term follow-up after splenectomy perofrmed for immune thrrombocytopenic purpura (ITP). Am J Hematol 2003 72 : 94 8.
21. Kojouri K, Vesely SK, Terrell DR, George JN. Splenectomy for adult patients with idiopathic thrombocytopenic purpura: a systematic review to assess long-term platelet count responses, prediction of response, and surgical complications. Blood 2004 104 : 2623 2634.
22. Vesely SK, Perdue JJ, Rizvi MA, Terrell DR, George JN. Management of adult patients with persistent idiopathic thrombocytopenic purpura following splenectomy: a systematic review. Ann Intern Med 2004 140 : 112 120.
23. Adler M, Ziglio E, eds. Gazing into the Oracle: The Delphi Method and its Application to Social Policy and Public Health. London : Jessica Kingsley Publishers, 1996.
24. Feudjo-Tepie MA, Robinson NJ, Bennett D. Prevalence of diagnosed chronic immune thrombocytopenia purpura in the US: analysis of a large US claims database: a rebuttal. J Thromb Haemost 2008 6 : 711 712.
25. Feudjo-Tepie MA, Le Roux G, Beach KJ, Bennett D, Robinson NJ. Comorbidities of Idiopathic Thrombocytopenic Purpura: A Population-Based Study. Adv Hematol 2009 doi :.
26. International Diabetes Federation. The human, social and economic impact of diabetes; 2009: http://www.idf.org/home/index.cfm?node=264. Accessed 5th April 2009.
27. Wolf-Maier K, Cooper RS, Banegas JR, et al. Hypertension Prevalence and Blood Pressure Levels in 6 European Countries, Canada, and the United States. JAMA 2003 289 : 2363 2369.
28. Rahman A, Isenberg DA. Systemic lupus erythematosus. N Engl J Med 2008 358 : 929 939.
29. Gernsheimer T. Epidemiology and pathophysiology of immune thrombocytopenic purpura. Eur J Haematol 2008 69 (Suppl 3 8.
30. Stevens W, Koene H, Zwaginga JJ, Vreugdenhil G. Chronic idiopathic thrombocytopenic purpura: present strategy, guidelines and new insights. Neth J Med 2006 64 : 356 363.
31. Bussel JB, Kuter DJ, Pullarkat V, Lyons RM, Guo M, Nichol JL. Safety and efficacy of long-term treatment with romiplostim in thrombocytopenic patients with chronic ITP. Blood 2009 113 : 2161 2171.
32. Rodeghiero F, Ruggeri M. Is splenectomy still the gold standard for the treatment of chronic ITP? Am J Hematol 2008 83 : 91 6.
33. Rodeghiero F. First-line therapies for immune thrombocytopenic purpura: re- evaluating the need to treat. Eur J Haematol 2008 69 : 19 26.
34. Johansson E, Engervall P, Landgren O, Grimfors G, Widel S, Rezai S, Björkholm M. Response to splenectomy is durable after a certain point in time in adult patients with chronic immune thrombocytopenic purpura. Eur J Haematol 2006 77 : 61 6.
35. Portielje JE, Westendorp RG, Kluin-Nelemans HC, Brand A. Morbidity and mortality in adults with idiopathic thrombocytopenic purpura. Blood 2001 97 : 2549 2554.
36. McMillan R, Wang L, Tomer A, Nichol J, Pistillo J. Suppression of in vitro megakaryocyte production by antiplatelet autoantibodies from adult patients with chronic ITP. Blood 2004 103 : 1364 1369.
37. Kuter DJ. New thrombopoietic growth factors. Blood 2007 109 : 4607 4616.
38. Godeau B, Bierling P. Treatment of idiopathic thrombocytopenic purpura in adults. Presse Med 2008 37 : 1292 1928.
39. Bussel JB, Provan D, Shamsi T, et al. Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomised, double-blind, placebo-controlled trial. Lancet 2009 373 : 641 648.