Is splenectomy still the gold standard for the treatment of chronic ITP?

American Journal of Hematology

Volumn 83, Issue 2, 2008, Pages 91-

  Rodeghiero, Francesco ^a   Ruggeri, Marco ^a  

^a SAN BORTOLO HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; ELTROMBOPAG; REMIPLISTIM; STEROID; THROMBOPOIETIN; THROMBOPOIETIN RECEPTOR;

BLEEDING; DRUG INDICATION; DRUG MEGADOSE; DRUG RESEARCH; EDITORIAL; GOLD STANDARD; HEADACHE; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; PRIORITY JOURNAL; SIDE EFFECT; SPLENECTOMY; TREATMENT INDICATION;

HUMANS; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; SPLENECTOMY; TREATMENT OUTCOME;

EID: 38349128561     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.21109     Document Type: Editorial

References (5)

1. Kojouri K, Vesely SK, Terrel DR, et al. Splenectomy for adult patients with idiopathic thrombocytopenic Purpura: A systematic review to assess long-term platelet count response, prediction of response and surgical complications. Blood 2004;104:2623-2634.
2. Mazzucconi MG, Fazi P, Bernasconi S, et al. Therapy with high-dose dexamethasone (HD-DXM) in previously untreated patients affected by idiopathic thrombocytopenic purpura: A GIMEMA experience. Blood 2007;109:1401-1407.
3. Bussel JB, Kuter DJ, George JN, et al. AMG 531, a thrombopoiesis - Stimulating protein, for chronic ITP. N Engl J Med 2006;355:1672-1681.
4. Jenkins JM, Williams D, Dneg Y, et al. Phase 1 clinical study of eltrombopag, an oral, nonpeptide thrombopoietin receptor agonist. Blood 2007;109:4739-4741.
5. Kuter DJ. New thropombopoietic growth factors. Blood 2007;109:4607-4616.