Management and outcome of steroid-resistant nephrotic syndrome in children

Iranian Journal of Kidney Diseases

Volumn 3, Issue 4, 2009, Pages 210-217

  Otukesh, Hasan ^a   Otukesh, Salman ^a   Mojtahedzadeh, Mona ^a   Hoseini, Rozita ^a   Fereshtehnejad, Seyed Mohammad ^a   Fard, Azam Riahi ^b   Sadigh, Nader ^a   Behzadi, Ashkan Heshmatzade ^a   Javadi, Ramila ^a   Hooman, Nakissa ^a   Mehrazma, Mitra ^b  

^a IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Child; Nephrotic syndrome; Steroids; Survival

Indexed keywords

AZATHIOPRINE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE;

ARTICLE; CHILD; CLINICAL FEATURE; CORTICOSTEROID THERAPY; DISEASE COURSE; DRUG RESPONSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HEMATURIA; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; IRAN; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; NEPHROTIC SYNDROME; ONSET AGE; PRESCHOOL CHILD; STEROID RESISTANT NEPHROTIC SYNDROME; SURVIVAL TIME; TREATMENT OUTCOME;

AGE FACTORS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DRUG RESISTANCE; FEMALE; GLUCOCORTICOIDS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; IRAN; KIDNEY FAILURE, CHRONIC; MALE; NEPHROTIC SYNDROME; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 73949157064     PISSN: 17358582     EISSN: 17358604     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. McKinney PA, Feltbower RG, Brocklebank JT, Fitzpatrick MM. Time trends and ethnic patterns of childhood nephrotic syndrome in Yorkshire, UK. Pediatr Nephrol. 2001;16:1040-4.
2. Wong W. Idiopathic nephrotic syndrome in New Zealand children, demographic, clinical features, initial management and outcome after twelve-month followup: results of a three-year national surveillance study. J Paediatr Child Health. 2007;43:337-41.
3. [No author listed]. The primary nephrotic syndrome in children. Identification of patients with minimal change nephrotic syndrome from initial response to prednisone. A report of the International Study of Kidney Disease in Children. J Pediatr. 1981;98:561-4.
4. Tarshish P, Tobin JN, Bernstein J, Edelmann CM, Jr. Prognostic significance of the early course of minimal change nephrotic syndrome: report of the International Study of Kidney Disease in Children. J Am Soc Nephrol. 1997;8:769-76.
5. Niaudet P. Steroid resistant idiopathic nephrotic syndrome in children. In: Textbook of pediatric nephrology. 15th ed. Philadelphia: WB Saunders; 2004. p. 558-73.
6. Ingulli E, Tejani A. Racial differences in the incidence and renal outcome of idiopathic focal segmental glomerulosclerosis in children. Pediatr Nephrol. 1991;5:393-7.
7. Bonilla-Felix M, Parra C, Dajani T, et al. Changing patterns in the histopathology of idiopathic nephrotic syndrome in children. Kidney Int. 1999;55:1885-90.
8. [No author listed]. Childhood nephrotic syndrome associated with diffuse mesangial hypercellularity. A report of the Southwest Pediatric Nephrology Study Group. Kidney Int. 1983;24:87-94.
9. Niaudet P. Treatment of childhood steroid-resistant idiopathic nephrosis with a combination of cyclosporine and prednisone. French Society of Pediatric Nephrology. J Pediatr. 1994;125:981-6.
10. Pena A, Bravo J, Melgosa M, et al. Steroid-resistant nephrotic syndrome: long-term evolution after sequential therapy. Pediatr Nephrol. 2007;22:1875-80.
11. Abrantes MM, Cardoso LS, Lima EM, et al. Clinical course of 110 children and adolescents with primary focal segmental glomerulosclerosis. Pediatr Nephrol. 2006;21:482-9.
12. Tarshish P, Tobin JN, Bernstein J, Edelmann CM, Jr. Cyclophosphamide does not benefit patients with focal segmental glomerulosclerosis. A report of the International Study of Kidney Disease in Children. Pediatr Nephrol. 1996;10:590-3.
13. Geary DF, Farine M, Thorner P, Baumal R. Response to cyclophosphamide in steroid-resistant focal segmental glomerulosclerosis: a reappraisal. Clin Nephrol. 1984;22:109-13.
14. Hodson EM, Craig JC. Therapies for steroid-resistant nephrotic syndrome. Pediatr Nephrol. 2008;23:1391-4.
15. Plank C, Kalb V, Hinkes B, Hildebrandt F, Gefeller O, Rascher W. Cyclosporin A is superior to cyclophosphamide in children with steroid-resistant nephrotic syndrome-a randomized controlled multicentre trial by the Arbeitsgemeinschaft fur Padiatrische Nephrologie. Pediatr Nephrol. 2008;23:1483-93.
16. Phadke K, Ballal S, Maiya V. Cyclosporine experience in nephrotic syndrome. Indian Pediatr. 1998;35:111-6.
17. Iyengar A, Karthik S, Kumar A, Biswas S, Phadke K. Cyclosporine in steroid dependent and resistant childhood nephrotic syndrome. Indian Pediatr. 2006;43:14-9.
18. Bayazit AK, Noyan A, Cengiz N, Anarat A. Mycophenolate mofetil in children with multidrug-resistant nephrotic syndrome. Clin Nephrol. 2004;61:25-9.
19. Cattran DC, Wang MM, Appel G, Matalon A, Briggs W. Mycophenolate mofetil in the treatment of focal segmental glomerulosclerosis. Clin Nephrol. 2004;62:405-11.
20. Cattran DC, Rao P. Long-term outcome in children and adults with classic focal segmental glomerulosclerosis. Am J Kidney Dis. 1998;32:72-9.