Detection of c-KIT and PDGFRA gene mutations in gastrointestinal stromal tumors: Comparison of DHPLC and DNA sequencing methods using a single population-based cohort

American Journal of Clinical Pathology

Volumn 133, Issue 1, 2010, Pages 149-155

  Battochio, Angeline ^a   Mohammed, Shamayel ^a   Winthrop, Debra ^a   Lefresne, Shilo ^a   Mulder, Karen ^a   Chu, Quincy ^a   O'Hara, Carolyn ^b   Lai, Raymond ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b DynaLIFE Dx   (Canada)

Author keywords

c KIT; Denaturing high pressure liquid chromatography; DNA sequencing; Gastrointestinal stromal tumor; Gene mutations; GIST; PDGFRA

Indexed keywords

PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; STEM CELL FACTOR RECEPTOR;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DNA SEQUENCE; EXON; FEMALE; GASTROINTESTINAL STROMAL TUMOR; GENE DELETION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; POINT MUTATION; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; BIOPSY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COHORT STUDIES; DNA MUTATIONAL ANALYSIS; EXONS; FEMALE; GASTROINTESTINAL STROMAL TUMORS; HUMANS; MALE; MIDDLE AGED; MUTATION; NUCLEIC ACID DENATURATION; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; YOUNG ADULT;

EID: 73949137372     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/AJCP1FNW7RGZFTYU     Document Type: Article

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