메뉴 건너뛰기




Volumn 33, Issue SUPPL. 1, 2009, Pages

Sickle cell disease at the dawn of the molecular era

Author keywords

Hemolytic anemia; Review; Sickle cell disease; Vasculopathy

Indexed keywords

APOLIPOPROTEIN A1; ARGININE; CELL ADHESION MOLECULE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; HEMOGLOBIN; HEMOGLOBIN F; INTERCELLULAR ADHESION MOLECULE 1; LACTATE DEHYDROGENASE; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE; PADGEM PROTEIN; VASCULAR CELL ADHESION MOLECULE 1;

EID: 73949134236     PISSN: 03630269     EISSN: 1532432X     Source Type: Journal    
DOI: 10.3109/03630260903347617     Document Type: Conference Paper
Times cited : (11)

References (94)
  • 1
    • 84928862267 scopus 로고
    • Peculiar elongated and sickle-shaped red blood corpuscules in a case of severe anemia
    • Herrick JB. Peculiar elongated and sickle-shaped red blood corpuscules in a case of severe anemia. Arch Int Med. 1910;6:517-521.
    • (1910) Arch Int Med. , vol.6 , pp. 517-521
    • Herrick, J.B.1
  • 2
    • 34147146124 scopus 로고
    • Abstract of discussion
    • Herrick JB. Abstract of discussion. J Am Med Assoc. 1924;83:16.
    • (1924) J Am Med Assoc. , vol.83 , pp. 16
    • Herrick, J.B.1
  • 3
    • 0006177989 scopus 로고
    • Further observations on sickle cell anemia
    • Sydenstricker VP. Further observations on sickle cell anemia. J Am Med Assoc. 1924;83:12-15.
    • (1924) J Am Med Assoc. , vol.83 , pp. 12-15
    • Sydenstricker, V.P.1
  • 5
    • 0000388374 scopus 로고
    • Studies on a case of sickle cell anemia
    • Scriver JR, Waugh TR. Studies on a case of sickle cell anemia. Can Med Assoc J. 1930;23:375-380.
    • (1930) Can Med Assoc J. , vol.23 , pp. 375-380
    • Scriver, J.R.1    Waugh, T.R.2
  • 6
    • 2342578493 scopus 로고
    • Molecular disease and evolution
    • Pauling L. Molecular disease and evolution. Bull N Y Acad Med. 1964;40:334-342.
    • (1964) Bull N y Acad Med. , vol.40 , pp. 334-342
    • Pauling, L.1
  • 8
    • 0000192487 scopus 로고
    • The inheritance of sickle cell anemia
    • Neel JV. The inheritance of sickle cell anemia. Science. 1949;110:64-66.
    • (1949) Science , vol.110 , pp. 64-66
    • Neel, J.V.1
  • 9
    • 0000343671 scopus 로고
    • The significance of the paucity of sickle cells in newborn Negro infants
    • Watson J, Stahman AW, Bilello FP. The significance of the paucity of sickle cells in newborn Negro infants. Am J Med Sci. 1948;215:419-423.
    • (1948) Am J Med Sci. , vol.215 , pp. 419-423
    • Watson, J.1    Stahman, A.W.2    Bilello, F.P.3
  • 10
    • 0001395034 scopus 로고
    • Abnormal human haemoglobins. I. the comparison of normal human and sickle-cell haemoglobins by fingerprinting
    • Ingram VM. Abnormal human haemoglobins. I. The comparison of normal human and sickle-cell haemoglobins by fingerprinting. Biochim Biophys Acta. 1958;28:539-545.
    • (1958) Biochim Biophys Acta. , Issue.28 , pp. 539-545
    • Ingram, V.M.1
  • 11
    • 10244252826 scopus 로고    scopus 로고
    • Polymerization and sickle cell disease: A molecular view
    • Ferrone FA. Polymerization and sickle cell disease: a molecular view. Microcirculation. 2004; 11:115-128.
    • (2004) Microcirculation , vol.11 , pp. 115-128
    • Ferrone, F.A.1
  • 12
    • 13844318521 scopus 로고    scopus 로고
    • Control of globin gene expression during development and erythroid differentiation
    • Stamatoyannopoulos G. Control of globin gene expression during development and erythroid differentiation. Exp Hematol. 2005;33:259-271.
    • (2005) Exp Hematol. , vol.33 , pp. 259-271
    • Stamatoyannopoulos, G.1
  • 13
    • 30444432407 scopus 로고    scopus 로고
    • Regulation of human fetal hemoglobin: New players, new complexities
    • Bank A. Regulation of human fetal hemoglobin: new players, new complexities. Blood. 2006;107:435-443.
    • (2006) Blood , vol.107 , pp. 435-443
    • Bank, A.1
  • 14
    • 0028291736 scopus 로고
    • Mortality in sickle cell disease. Life expectancy and risk factors for early death
    • Platt OS, Brambilla DJ, Rosse WF, et al. Mortality in sickle cell disease. Life expectancy and risk factors for early death. N Engl J Med. 1994;330:1639-1644.
    • (1994) N Engl J Med. , vol.330 , pp. 1639-1644
    • Platt, O.S.1    Brambilla, D.J.2    Rosse, W.F.3
  • 17
    • 0036908599 scopus 로고    scopus 로고
    • Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
    • Reiter CD, Wang X, Tanus-Santos JE, et al. Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med. 2002;8:1383-1389.
    • (2002) Nat Med. , vol.8 , pp. 1383-1389
    • Reiter, C.D.1    Wang, X.2    Tanus-Santos, J.E.3
  • 18
    • 33646231295 scopus 로고    scopus 로고
    • Cardiopulmonary complications of sickle cell disease: Role of nitric oxide and hemolytic anemia
    • Gladwin MT, Kato GJ. Cardiopulmonary complications of sickle cell disease: role of nitric oxide and hemolytic anemia. Hematology Am Soc Hematol Educ Program. 2005;51-57.
    • (2005) Hematology Am Soc Hematol Educ Program , pp. 51-57
    • Gladwin, M.T.1    Kato, G.J.2
  • 19
    • 0022021390 scopus 로고
    • Auto-oxidation and a membrane-associated 'Fenton reagent': A possible explanation for development of membrane lesions in sickle erythrocytes
    • Hebbel RP. Auto-oxidation and a membrane-associated 'Fenton reagent': a possible explanation for development of membrane lesions in sickle erythrocytes. Clin Haematol. 1985;14:129-140.
    • (1985) Clin Haematol. , vol.14 , pp. 129-140
    • Hebbel, R.P.1
  • 20
    • 23244453721 scopus 로고    scopus 로고
    • Plasma levels of asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase inhibitor, are elevated in sickle cell disease
    • Schnog JB, Teerlink T, van der Dijs FP, Duits AJ, Muskiet FA. Plasma levels of asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase inhibitor, are elevated in sickle cell disease. Ann Hematol. 2005;84:282-286.
    • (2005) Ann Hematol. , vol.84 , pp. 282-286
    • Schnog, J.B.1    Teerlink, T.2    Van Der Dijs, F.P.3    Duits, A.J.4    Muskiet, F.A.5
  • 21
    • 45749100959 scopus 로고    scopus 로고
    • Plasma concentrations of asymmetric dimethylarginine, an endogenous nitric oxide synthase inhibitor, are elevated in sickle cell patients but do not increase further during painful crisis
    • CURAMA Study Group
    • Landburg PP, Teerlink T, Muskiet FA, Duits AJ, Schnog JJ, CURAMA Study Group. Plasma concentrations of asymmetric dimethylarginine, an endogenous nitric oxide synthase inhibitor, are elevated in sickle cell patients but do not increase further during painful crisis. Am J Hematol. 2008;83:577-579.
    • (2008) Am J Hematol. , vol.83 , pp. 577-579
    • Landburg, P.P.1    Teerlink, T.2    Muskiet, F.A.3    Duits, A.J.4    Schnog, J.J.5
  • 22
    • 10744233940 scopus 로고    scopus 로고
    • Pulmonary hypertension as a risk factor for death in patients with sickle cell disease
    • Gladwin MT, Sachdev V, Jison ML, et al. Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med. 2004;350:886-895.
    • (2004) N Engl J Med. , vol.350 , pp. 886-895
    • Gladwin, M.T.1    Sachdev, V.2    Jison, M.L.3
  • 23
    • 14244257951 scopus 로고    scopus 로고
    • Pulmonary hypertension in sickle cell disease
    • Ataga KI, Sood N, De GG, et al. Pulmonary hypertension in sickle cell disease. Am J Med. 2004;117:665-669.
    • (2004) Am J Med. , vol.117 , pp. 665-669
    • Ataga, K.I.1    Sood, N.2
  • 24
    • 38349071895 scopus 로고    scopus 로고
    • Pulmonary hypertension associated with sickle cell disease: Clinical and laboratory endpoints and disease outcomes
    • De Castro LM, Jonassaint JC, Graham FL, Ashley-Koch A, Telen MJ. Pulmonary hypertension associated with sickle cell disease: clinical and laboratory endpoints and disease outcomes. Am J Hematol. 2008;83:19-25.
    • (2008) Am J Hematol. , vol.83 , pp. 19-25
    • De Castro, L.M.1    Jonassaint, J.C.2    Graham, F.L.3    Ashley-Koch, A.4    Telen, M.J.5
  • 25
    • 33744810662 scopus 로고    scopus 로고
    • Pulmonary hypertension in patients with sickle cell disease: A longitudinal study
    • Ataga KI, Moore CG, Jones S, et al. Pulmonary hypertension in patients with sickle cell disease: a longitudinal study. Br J Haematol. 2006;134:109-115.
    • (2006) Br J Haematol. , vol.134 , pp. 109-115
    • Ataga, K.I.1    Moore, C.G.2    Jones, S.3
  • 26
    • 33846338501 scopus 로고    scopus 로고
    • Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease
    • Sachdev V, Machado RF, Shizukuda Y, et al. Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease. J Am Coll Cardiol. 2007;49:472-479.
    • (2007) J Am Coll Cardiol. , vol.49 , pp. 472-479
    • Sachdev, V.1    MacHado, R.F.2    Shizukuda, Y.3
  • 27
    • 33746040474 scopus 로고    scopus 로고
    • N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease
    • Machado RF, Anthi A, Steinberg MH, et al. N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease. J Am Med Assoc. 2006;296:310-318.
    • (2006) J Am Med Assoc. , vol.296 , pp. 310-318
    • MacHado, R.F.1    Anthi, A.2    Steinberg, M.H.3
  • 28
    • 57449112518 scopus 로고    scopus 로고
    • Evolution of novel small-molecule therapeutics targeting sickle cell vasculopathy
    • Kato GJ, Gladwin MT. Evolution of novel small-molecule therapeutics targeting sickle cell vasculopathy. J Am Med Assoc. 2008;300:2638-2646.
    • (2008) J Am Med Assoc. , vol.300 , pp. 2638-2646
    • Kato, G.J.1    Gladwin, M.T.2
  • 30
    • 0037101989 scopus 로고    scopus 로고
    • Sildenafil relieves priapism in patients with sickle cell disease
    • Bialecki ES, Bridges KR. Sildenafil relieves priapism in patients with sickle cell disease. Am J Med. 2002;113:252.
    • (2002) Am J Med. , vol.113 , pp. 252
    • Bialecki, E.S.1    Bridges, K.R.2
  • 31
    • 33646849221 scopus 로고    scopus 로고
    • Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism
    • Burnett AL, Bivalacqua TJ, Champion HC, Musicki B. Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism. Urology. 2006;67:1043-1048.
    • (2006) Urology , vol.67 , pp. 1043-1048
    • Burnett, A.L.1    Bivalacqua, T.J.2    Champion, H.C.3    Musicki, B.4
  • 32
    • 0031965089 scopus 로고    scopus 로고
    • Cerebrovascular accidents in sickle cell disease: Rates and risk factors
    • Ohene-Frempong K, Weiner SJ, Sleeper LA, et al. Cerebrovascular accidents in sickle cell disease: rates and risk factors. Blood. 1998;91:288-294.
    • (1998) Blood , vol.91 , pp. 288-294
    • Ohene-Frempong, K.1    Weiner, S.J.2    Sleeper, L.A.3
  • 33
    • 33745141905 scopus 로고    scopus 로고
    • Regular transfusion lowers plasma free hemoglobin in children with sickle-cell disease at risk for stroke
    • Lezcano NE, Odo N, Kutlar A, Brambilla D, Adams RJ. Regular transfusion lowers plasma free hemoglobin in children with sickle-cell disease at risk for stroke. Stroke. 2006;37:1424-1426.
    • (2006) Stroke , vol.37 , pp. 1424-1426
    • Lezcano, N.E.1    Odo, N.2    Kutlar, A.3    Brambilla, D.4    Adams, R.J.5
  • 34
    • 0032474692 scopus 로고    scopus 로고
    • Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography
    • Adams RJ, McKie VC, Hsu L, et al. Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography. N Engl J Med. 1998; 339:5-11.
    • (1998) N Engl J Med. , vol.339 , pp. 5-11
    • Adams, R.J.1    McKie, V.C.2    Hsu, L.3
  • 35
    • 0032989606 scopus 로고    scopus 로고
    • Silent cerebral infarcts in sickle cell anemia: A risk factor analysis. the cooperative study of sickle cell disease
    • Kinney TR, Sleeper LA, Wang WC, et al. Silent cerebral infarcts in sickle cell anemia: a risk factor analysis. The cooperative study of sickle cell disease. Pediatrics. 1999;103:640-645.
    • (1999) Pediatrics , vol.103 , pp. 640-645
    • Kinney, T.R.1    Sleeper, L.A.2    Wang, W.C.3
  • 36
    • 21444441271 scopus 로고    scopus 로고
    • Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension and mortality in sickle cell disease
    • Morris CR, Kato GJ, Poljakovic M, et al. Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension and mortality in sickle cell disease. J Am Med Assoc. 2005;294:81-90.
    • (2005) J Am Med Assoc. , vol.294 , pp. 81-90
    • Morris, C.R.1    Kato, G.J.2    Poljakovic, M.3
  • 37
    • 33644775612 scopus 로고    scopus 로고
    • Lactate dehydrogenase as a biomarker of hemolysisassociated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension and death in patients with sickle cell disease
    • Kato GJ, McGowan VR, Machado RF, et al. Lactate dehydrogenase as a biomarker of hemolysisassociated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension and death in patients with sickle cell disease. Blood. 2006;107:2279-2285.
    • (2006) Blood , vol.107 , pp. 2279-2285
    • Kato, G.J.1    McGowan, V.R.2    MacHado, R.F.3
  • 38
    • 33646271370 scopus 로고    scopus 로고
    • Sickel cell leg ulcers: Associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway
    • Nolan VG, Adewoye A, Baldwin C, et al. Sickel cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathway. Br J Haematol. 2006;133:570-578.
    • (2006) Br J Haematol. , vol.133 , pp. 570-578
    • Nolan, V.G.1    Adewoye, A.2    Baldwin, C.3
  • 39
    • 0035437137 scopus 로고    scopus 로고
    • Characterization of the phosphatidylserine-exposing subpopulation of sickle cells
    • de Jong K, Larkin SK, Styles LA, Bookchin RM, Kuypers FA. Characterization of the phosphatidylserine-exposing subpopulation of sickle cells. Blood. 2001;98:860-867.
    • (2001) Blood , vol.98 , pp. 860-867
    • De Jong, K.1    Larkin, S.K.2    Styles, L.A.3    Bookchin, R.M.4    Kuypers, F.A.5
  • 40
    • 0037902091 scopus 로고    scopus 로고
    • Phosphatidylserine externalization in sickle red blood cells: Associations with cell age, density, and hemoglobin F
    • Yasin Z, Witting S, Palascak MB, Joiner CH, Rucknagel DL, Franco RS. Phosphatidylserine externalization in sickle red blood cells: associations with cell age, density, and hemoglobin F. Blood. 2003; 102:365-370.
    • (2003) Blood , vol.102 , pp. 365-370
    • Yasin, Z.1    Witting, S.2    Palascak, M.B.3    Joiner, C.H.4    Rucknagel, D.L.5    Franco, R.S.6
  • 41
    • 0019440273 scopus 로고
    • Sickled erythrocytes accelerate clotting in vitro: An effect of abnormal membrane lipid asymmetry
    • Chiu D, Lubin B, Roelofsen B, van Deenen LL. Sickled erythrocytes accelerate clotting in vitro: an effect of abnormal membrane lipid asymmetry. Blood. 1981;58:398-401.
    • (1981) Blood , vol.58 , pp. 398-401
    • Chiu, D.1    Lubin, B.2    Roelofsen, B.3    Van Deenen, L.L.4
  • 42
    • 0036039730 scopus 로고    scopus 로고
    • Relationship between hypercoagulable state and erythrocyte phosphatidylserine exposure in splenectomized haemoglobin E/beta-thalassaemic patients
    • Atichartakarn V, Angchaisuksiri P, Aryurachai K, et al. Relationship between hypercoagulable state and erythrocyte phosphatidylserine exposure in splenectomized haemoglobin E/beta-thalassaemic patients. Br J Haematol. 2002;118:893-898.
    • (2002) Br J Haematol. , vol.118 , pp. 893-898
    • Atichartakarn, V.1    Angchaisuksiri, P.2    Aryurachai, K.3
  • 43
    • 0141680833 scopus 로고    scopus 로고
    • In vivo platelet activation and hyperaggregation in hemoglobin E/beta-thalassemia: A consequence of splenectomy
    • Atichartakarn V, Angchaisuksiri P, Aryurachai K, Chuncharunee S, Thakkinstian A. In vivo platelet activation and hyperaggregation in hemoglobin E/beta-thalassemia: a consequence of splenectomy. Int J Hematol. 2003;77:299-303.
    • (2003) Int J Hematol. , vol.77 , pp. 299-303
    • Atichartakarn, V.1    Angchaisuksiri, P.2    Aryurachai, K.3    Chuncharunee, S.4    Thakkinstian, A.5
  • 44
    • 0034970144 scopus 로고    scopus 로고
    • Recurrent thromboembolic disease following splenectomy for pyruvate kinase deficiency
    • Chou R, DeLoughery TG. Recurrent thromboembolic disease following splenectomy for pyruvate kinase deficiency. Am J Hematol. 2001;67:197-199.
    • (2001) Am J Hematol. , vol.67 , pp. 197-199
    • Chou, R.1    Deloughery, T.G.2
  • 45
    • 0031974567 scopus 로고    scopus 로고
    • Hereditary spherocytosis, thrombocytosis, and chronic pulmonary emboli: A case report and review of the literature
    • Hayag-Barin JE, Smith RE, Tucker FC Jr.. Hereditary spherocytosis, thrombocytosis, and chronic pulmonary emboli: a case report and review of the literature. Am J Hematol. 1998;57:82-84.
    • (1998) Am J Hematol. , vol.57 , pp. 82-84
    • Hayag-Barin, J.E.1    Smith, R.E.2    Tucker Jr., F.C.3
  • 47
    • 0029872495 scopus 로고    scopus 로고
    • Thrombo-embolic disease after splenectomy for hereditary stomatocytosis
    • Stewart GW, Amess JA, Eber SW, et al. Thrombo-embolic disease after splenectomy for hereditary stomatocytosis. Br J Haematol. 1996;93:303-310.
    • (1996) Br J Haematol. , vol.93 , pp. 303-310
    • Stewart, G.W.1    Amess, J.A.2    Eber, S.W.3
  • 48
    • 0036493303 scopus 로고    scopus 로고
    • Role of erythrocyte phosphatidylserine in sickle red cell-endothelial adhesion
    • Setty BN, Kulkarni S, Stuart MJ. Role of erythrocyte phosphatidylserine in sickle red cell-endothelial adhesion. Blood. 2002;99:1564-1571.
    • (2002) Blood , vol.99 , pp. 1564-1571
    • Setty, B.N.1    Kulkarni, S.2    Stuart, M.J.3
  • 49
    • 0035761409 scopus 로고    scopus 로고
    • Thrombophilia in sickle cell disease: The red cell connection
    • Setty BN, Rao AK, Stuart MJ. Thrombophilia in sickle cell disease: the red cell connection. Blood. 2001;98:3228-3233.
    • (2001) Blood , vol.98 , pp. 3228-3233
    • Setty, B.N.1    Rao, A.K.2    Stuart, M.J.3
  • 50
    • 0035113766 scopus 로고    scopus 로고
    • Hemostatic alterations in sickle cell disease: Relationships to disease pathophysiology
    • Stuart MJ, Setty BN. Hemostatic alterations in sickle cell disease: relationships to disease pathophysiology. Pediatr Pathol Mol Med. 2001;20:27-46.
    • (2001) Pediatr Pathol Mol Med. , vol.20 , pp. 27-46
    • Stuart, M.J.1    Setty, B.N.2
  • 51
    • 5444273795 scopus 로고    scopus 로고
    • The role of phosphatidylserine in recognition and removal of erythrocytes
    • Kuypers FJ, de Jong K. The role of phosphatidylserine in recognition and removal of erythrocytes. Cell Mol Biol. 2004;50:147-158.
    • (2004) Cell Mol Biol. , vol.50 , pp. 147-158
    • Kuypers, F.J.1    De Jong, K.2
  • 52
    • 0020067938 scopus 로고
    • Haematological factors associated with avascular necrosis of the femoral head in homozygous sickle cell disease
    • Hawker H, Neilson H, Hayes RJ, Serjeant GR. Haematological factors associated with avascular necrosis of the femoral head in homozygous sickle cell disease. Br J Haematol. 1982;50:29-34.
    • (1982) Br J Haematol. , vol.50 , pp. 29-34
    • Hawker, H.1    Neilson, H.2    Hayes, R.J.3    Serjeant, G.R.4
  • 53
    • 0028234283 scopus 로고
    • The acute chest syndrome in sickle cell disease: Incidence and risk factors. the cooperative study of sickle cell disease
    • Castro O, Brambilla DJ, Thorington B, et al. The acute chest syndrome in sickle cell disease: incidence and risk factors. The cooperative study of sickle cell disease. Blood. 1994;84:643-649.
    • (1994) Blood , vol.84 , pp. 643-649
    • Castro, O.1    Brambilla, D.J.2    Thorington, B.3
  • 54
    • 0026605946 scopus 로고
    • Fetal haemoglobin and early manifestations of homozygous sickle cell disease
    • Bailey K, Morris JS, Thomas P, Serjeant GR. Fetal haemoglobin and early manifestations of homozygous sickle cell disease. Arch Dis Child. 1992;67:517-520.
    • (1992) Arch Dis Child. , vol.67 , pp. 517-520
    • Bailey, K.1    Morris, J.S.2    Thomas, P.3    Serjeant, G.R.4
  • 55
    • 20044367676 scopus 로고    scopus 로고
    • Predicting clinical severity in sickle cell anaemia
    • Steinberg MH. Predicting clinical severity in sickle cell anaemia. Br J Haematol. 2005;129: 465-481.
    • (2005) Br J Haematol. , vol.129 , pp. 465-481
    • Steinberg, M.H.1
  • 56
  • 58
    • 16844366938 scopus 로고    scopus 로고
    • Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia
    • Sebastiani P, Ramoni MF, Nolan V, Baldwin CT, Steinberg MH. Genetic dissection and prognostic modeling of overt stroke in sickle cell anemia. Nat Genet. 2005;37:435-440.
    • (2005) Nat Genet. , vol.37 , pp. 435-440
    • Sebastiani, P.1    Ramoni, M.F.2    Nolan, V.3    Baldwin, C.T.4    Steinberg, M.H.5
  • 60
    • 0020081165 scopus 로고
    • Concurrent sickle-cell anemia and alpha-thalassemia: Effect on severity of anemia
    • Embury SH, Dozy AM, Miller J, et al. Concurrent sickle-cell anemia and alpha-thalassemia: effect on severity of anemia. N Engl J Med. 1982;306:270-274.
    • (1982) N Engl J Med. , vol.306 , pp. 270-274
    • Embury, S.H.1    Dozy, A.M.2    Miller, J.3
  • 61
    • 0021254222 scopus 로고
    • Effects of thalassemia and microcytosis on the hematologic and vasoocclusive severity of sickle cell anemia
    • Steinberg MH, Rosenstock W, Coleman MB, et al. Effects of thalassemia and microcytosis on the hematologic and vasoocclusive severity of sickle cell anemia. Blood. 1984;63:1353-1360.
    • (1984) Blood , vol.63 , pp. 1353-1360
    • Steinberg, M.H.1    Rosenstock, W.2    Coleman, M.B.3
  • 62
    • 0024467330 scopus 로고
    • Leg ulcers in patients with sickle cell disease
    • Koshy M, Entsuah R, Koranda A, et al. Leg ulcers in patients with sickle cell disease. Blood. 1989; 74:1403-1408.
    • (1989) Blood , vol.74 , pp. 1403-1408
    • Koshy, M.1    Entsuah, R.2    Koranda, A.3
  • 63
    • 0020057099 scopus 로고
    • The interaction of alpha-thalassemia and homozygous sicklecell disease
    • Higgs DR, Aldridge BE, Lamb J, et al. The interaction of alpha-thalassemia and homozygous sicklecell disease. N Engl J Med. 1982;306:1441-1446.
    • (1982) N Engl J Med. , vol.306 , pp. 1441-1446
    • Higgs, D.R.1    Aldridge, B.E.2    Lamb, J.3
  • 64
    • 0028231790 scopus 로고
    • Alpha thalassemia and stroke risk in sickle cell anemia
    • Adams RJ, Kutlar A, McKie V, et al. Alpha thalassemia and stroke risk in sickle cell anemia. Am J Hematol. 1994;45:279-282.
    • (1994) Am J Hematol. , vol.45 , pp. 279-282
    • Adams, R.J.1    Kutlar, A.2    McKie, V.3
  • 65
    • 0042570486 scopus 로고    scopus 로고
    • Alpha thalassemia is associated with decreased risk of abnormal transcranial Doppler ultrasonography in children with sickle cell anemia
    • Hsu LL, Miller ST, Wright E, et al. Alpha thalassemia is associated with decreased risk of abnormal transcranial Doppler ultrasonography in children with sickle cell anemia. J Pediatr Hematol Oncol. 2003;25:622-628.
    • (2003) J Pediatr Hematol Oncol. , vol.25 , pp. 622-628
    • Hsu, L.L.1    Miller, S.T.2    Wright, E.3
  • 66
    • 0033857950 scopus 로고    scopus 로고
    • Acute clinical events in 299 homozygous sickle cell patients living in France
    • French study group on sickle cell disease
    • Neonato MG, Guilloud-Bataille M, Beauvais P, et al. Acute clinical events in 299 homozygous sickle cell patients living in France. French study group on sickle cell disease. Eur J Haematol. 2000;65: 155-164.
    • (2000) Eur J Haematol. , vol.65 , pp. 155-164
    • Neonato, M.G.1    Guilloud-Bataille, M.2    Beauvais, P.3
  • 67
    • 0029017748 scopus 로고
    • Clinical events in the first decade in a cohort of infants with sickle cell disease. Cooperative study of sickle cell disease
    • Gill FM, Sleeper LA, Weiner SJ, et al. Clinical events in the first decade in a cohort of infants with sickle cell disease. Cooperative study of sickle cell disease. Blood. 1995;86:776-783.
    • (1995) Blood , vol.86 , pp. 776-783
    • Gill, F.M.1    Sleeper, L.A.2    Weiner, S.J.3
  • 68
    • 0028810664 scopus 로고
    • Paradoxical increase of painful crises in sickle cell patients with alpha-thalassemia
    • Billett HH, Nagel RL, Fabry ME. Paradoxical increase of painful crises in sickle cell patients with alpha-thalassemia. Blood. 1995;86:4382.
    • (1995) Blood , vol.86 , pp. 4382
    • Billett, H.H.1    Nagel, R.L.2    Fabry, M.E.3
  • 69
    • 0022454177 scopus 로고
    • The percentage of dense red cells does not predict incidence of sickle cell painful crisis
    • Billett HH, Kim K, Fabry ME, Nagel RL. The percentage of dense red cells does not predict incidence of sickle cell painful crisis. Blood. 1986;68:301-303.
    • (1986) Blood , vol.68 , pp. 301-303
    • Billett, H.H.1    Kim, K.2    Fabry, M.E.3    Nagel, R.L.4
  • 70
    • 0025973855 scopus 로고
    • Is the painful crisis of sickle-cell disease due to sickling?
    • Bailey S, Higgs DR, Morris J, Serjeant GR. Is the painful crisis of sickle-cell disease due to sickling? Lancet. 1991;337:735.
    • (1991) Lancet , vol.337 , pp. 735
    • Bailey, S.1    Higgs, D.R.2    Morris, J.3    Serjeant, G.R.4
  • 71
    • 0026076686 scopus 로고
    • Sickle cell disease as a cause of osteonecrosis of the femoral head
    • Milner PF, Kraus AP, Sebes JI, et al. Sickle cell disease as a cause of osteonecrosis of the femoral head. N Engl J Med. 1991;325:1476-1481.
    • (1991) N Engl J Med. , vol.325 , pp. 1476-1481
    • Milner, P.F.1    Kraus, A.P.2    Sebes, J.I.3
  • 72
    • 0024892053 scopus 로고
    • The prevalence of avascular necrosis in sickle cell anemia: Correlation with alpha-thalassemia
    • Ballas SK, Talacki CA, Rao VM, Steiner RM. The prevalence of avascular necrosis in sickle cell anemia: correlation with alpha-thalassemia. Hemoglobin. 1989;13:649-655.
    • (1989) Hemoglobin , vol.13 , pp. 649-655
    • Ballas, S.K.1    Talacki, C.A.2    Rao, V.M.3    Steiner, R.M.4
  • 73
    • 34147141453 scopus 로고    scopus 로고
    • Sickle cell disease: Old discoveries, new concepts, and future promise
    • Frenette PS, Atweh GF. Sickle cell disease: old discoveries, new concepts, and future promise. J Clin Invest. 2007;117:850-858.
    • (2007) J Clin Invest. , vol.117 , pp. 850-858
    • Frenette, P.S.1    Atweh, G.F.2
  • 74
    • 27244435213 scopus 로고    scopus 로고
    • Levels of soluble endothelium-derived adhesion molecules in patients with sickle cell disease are associated with pulmonary hypertension, organ dysfunction, and mortality
    • Kato GJ, Martyr S, Blackwelder WC, et al. Levels of soluble endothelium-derived adhesion molecules in patients with sickle cell disease are associated with pulmonary hypertension, organ dysfunction, and mortality. Br J Haematol. 2005;130:943-953.
    • (2005) Br J Haematol. , vol.130 , pp. 943-953
    • Kato, G.J.1    Martyr, S.2    Blackwelder, W.C.3
  • 75
    • 45749141769 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension and left-sided heart disease in sickle cell disease: Clinical characteristics and association with soluble adhesion molecule expression
    • Klings ES, Anton Bland D, Rosenman D, et al. Pulmonary arterial hypertension and left-sided heart disease in sickle cell disease: clinical characteristics and association with soluble adhesion molecule expression. Am J Hematol. 2008;83:547-553.
    • (2008) Am J Hematol. , vol.83 , pp. 547-553
    • Klings, E.S.1    Anton Bland, D.2    Rosenman, D.3
  • 77
    • 15944398355 scopus 로고    scopus 로고
    • The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: A novel mechanism of human disease
    • Rother RP, Bell L, Hillmen P, Gladwin MT. The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease. J Am Med Assoc. 2005;293: 1653-1662.
    • (2005) J Am Med Assoc. , vol.293 , pp. 1653-1662
    • Rother, R.P.1    Bell, L.2    Hillmen, P.3    Gladwin, M.T.4
  • 78
    • 0015216974 scopus 로고
    • The binding of hemoglobin to haptoglobin and its relation to subunit dissociation of hemoglobin
    • Nagel RL, Gibson QH. The binding of hemoglobin to haptoglobin and its relation to subunit dissociation of hemoglobin. J Biol Chem. 1971;246:69-73.
    • (1971) J Biol Chem. , vol.246 , pp. 69-73
    • Nagel, R.L.1    Gibson, Q.H.2
  • 79
    • 0035843134 scopus 로고    scopus 로고
    • Identification of the haemoglobin scavenger receptor
    • Kristiansen M, Graversen JH, Jacobsen C, et al. Identification of the haemoglobin scavenger receptor. Nature. 2001;409:198-201.
    • (2001) Nature , vol.409 , pp. 198-201
    • Kristiansen, M.1    Graversen, J.H.2    Jacobsen, C.3
  • 80
    • 4243550127 scopus 로고    scopus 로고
    • Heme oxygenase/carbon monoxide signaling pathways: Regulation and functional significance
    • Ryter SW, Otterbein LE, Morse D, Choi AM. Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance. Mol Cell Biochem. 2002;234-235:249-263.
    • (2002) Mol Cell Biochem. , vol.234-235 , pp. 249-263
    • Ryter, S.W.1    Otterbein, L.E.2    Morse, D.3    Choi, A.M.4
  • 82
    • 0034071424 scopus 로고    scopus 로고
    • Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway
    • Otterbein LE, Bach FH, Alam J, et al. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med. 2000;6:422-428.
    • (2000) Nat Med. , vol.6 , pp. 422-428
    • Otterbein, L.E.1    Bach, F.H.2    Alam, J.3
  • 83
    • 0035895080 scopus 로고    scopus 로고
    • Structure-function analysis of the antioxidant properties of haptoglobin
    • Melamed-Frank M, Lache O, Enav BI, et al. Structure-function analysis of the antioxidant properties of haptoglobin. Blood. 2001;98:3693-3698.
    • (2001) Blood , vol.98 , pp. 3693-3698
    • Melamed-Frank, M.1    Lache, O.2    Enav, B.I.3
  • 84
    • 33644841363 scopus 로고    scopus 로고
    • Leukocyte adhesion and the pathophysiology of sickle cell disease
    • Okpala I. Leukocyte adhesion and the pathophysiology of sickle cell disease. Curr Opin Hematol. 2006;13:40-44.
    • (2006) Curr Opin Hematol. , vol.13 , pp. 40-44
    • Okpala, I.1
  • 85
    • 10244278094 scopus 로고    scopus 로고
    • Sickle cell vasoocclusion: Heterotypic, multicellular aggregations driven by leukocyte adhesion
    • Frenette PS. Sickle cell vasoocclusion: heterotypic, multicellular aggregations driven by leukocyte adhesion. Microcirculation. 2004;11:167-177.
    • (2004) Microcirculation , vol.11 , pp. 167-177
    • Frenette, P.S.1
  • 86
    • 0027526219 scopus 로고
    • The damaging potential of leukocyte activation in the microcirculation
    • Schmid-Schonbein GW. The damaging potential of leukocyte activation in the microcirculation. Angiology. 1993;44:45-56.
    • (1993) Angiology , vol.44 , pp. 45-56
    • Schmid-Schonbein, G.W.1
  • 87
    • 0023241610 scopus 로고
    • Leukocyte-endothelium adhesion: Microhemodynamics in mesentery of the cat
    • House SD, Lipowsky HH. Leukocyte-endothelium adhesion: microhemodynamics in mesentery of the cat. Microvasc Res. 1987;34:363-379.
    • (1987) Microvasc Res. , vol.34 , pp. 363-379
    • House, S.D.1    Lipowsky, H.H.2
  • 89
    • 0030030905 scopus 로고    scopus 로고
    • Susceptibility to infection and altered hematopoiesis in mice deficient in both P-and E-selectins
    • Frenette PS, Mayadas TN, Rayburn H, Hynes RO, Wagner DD. Susceptibility to infection and altered hematopoiesis in mice deficient in both P-and E-selectins. Cell. 1996;84:563-574.
    • (1996) Cell , vol.84 , pp. 563-574
    • Frenette, P.S.1    Mayadas, T.N.2    Rayburn, H.3    Hynes, R.O.4    Wagner, D.D.5
  • 90
    • 0029998910 scopus 로고    scopus 로고
    • Sickle erythrocytes adhere to polymorphonuclear neutrophils and activate the neutrophil respiratory burst
    • Hofstra TC, Kalra VK, Meiselman HJ, Coates TD. Sickle erythrocytes adhere to polymorphonuclear neutrophils and activate the neutrophil respiratory burst. Blood. 1996;87:4440-4447.
    • (1996) Blood , vol.87 , pp. 4440-4447
    • Hofstra, T.C.1    Kalra, V.K.2    Meiselman, H.J.3    Coates, T.D.4
  • 91
    • 33847675756 scopus 로고    scopus 로고
    • Imaging receptor microdomains on leukocyte subsets in live mice
    • Chiang EY, Hidalgo A, Chang J, Frenette PS. Imaging receptor microdomains on leukocyte subsets in live mice. Nat Methods. 2007;4:219-222.
    • (2007) Nat Methods , vol.4 , pp. 219-222
    • Chiang, E.Y.1    Hidalgo, A.2    Chang, J.3    Frenette, P.S.4
  • 93
    • 0034642592 scopus 로고    scopus 로고
    • Prediction of adverse outcomes in children with sickle cell disease
    • Miller ST, Sleeper LA, Pegelow CH, et al. Prediction of adverse outcomes in children with sickle cell disease. N Engl J Med. 2000;342:83-89.
    • (2000) N Engl J Med. , vol.342 , pp. 83-89
    • Miller, S.T.1    Sleeper, L.A.2    Pegelow, C.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.