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Volumn 67, Issue 10, 2009, Pages 992-1000

Synthesis of trifluoromethyl-containing pyridines and their applications to biologically active molecules

Author keywords

Applications; Biologically active molecules; Heteroaromatic compounds; Pyridines; Synthesis; Trifluoromethyl group

Indexed keywords

BIOLOGICALLY ACTIVE COMPOUNDS; BIOLOGICALLY ACTIVE MOLECULES; DRUG CANDIDATES; HETEROAROMATIC COMPOUNDS; NATURAL PRODUCTS; ORGANIC MATERIALS; PHYSICOCHEMICAL PROPERTY; SYNTHESIS; TRIFLUOROMETHYL; TRIFLUOROMETHYL GROUP;

EID: 73949133827     PISSN: 00379980     EISSN: None     Source Type: Journal    
DOI: 10.5059/yukigoseikyokaishi.67.992     Document Type: Article
Times cited : (17)

References (78)
  • 3
    • 73949147557 scopus 로고    scopus 로고
    • P. Lindberg, A. Branstrbm, B
    • (c) P. Lindberg, A. Branstrbm, B.
  • 8
    • 73949141181 scopus 로고    scopus 로고
    • Biologically Active Organofluorine Compounds ed. by N. Ishikawa, CMC, Tokyo, 1990;
    • (a) "Biologically Active Organofluorine Compounds" ed. by N. Ishikawa, CMC, Tokyo, 1990;
  • 9
    • 73949113605 scopus 로고    scopus 로고
    • Fluorine in Organic Chemistry ed. by R. D. Chambers, Blackwell Publishing, Oxford, UK (2004)
    • (b) "Fluorine in Organic Chemistry" ed. by R. D. Chambers, Blackwell Publishing, Oxford, UK (2004)
  • 11
    • 13444266910 scopus 로고    scopus 로고
    • Celecoxib: T. D. Penning, J. J. Talley, S. R. Bertenshaw, J. S. Carter, P. W. Collins, S. Docter, M. J. Graneto, L. F. Lee, J. W. Malecha, J. M. Miyashiro, R. S. Rogers, D. J. Rogier, S. S. Yu, G. D. Anderson, C. M. Koboldt, W. E. Perkins, K. Seibert, A. W. Veen- huizen, Y. Y. Zhang, P. C. Isakson, J. Med. Chem., 40, 1347 (1997);
    • Celecoxib: T. D. Penning, J. J. Talley, S. R. Bertenshaw, J. S. Carter, P. W. Collins, S. Docter, M. J. Graneto, L. F. Lee, J. W. Malecha, J. M. Miyashiro, R. S. Rogers, D. J. Rogier, S. S. Yu, G. D. Anderson, C. M. Koboldt, W. E. Perkins, K. Seibert, A. W. Veen- huizen, Y. Y. Zhang, P. C. Isakson, J. Med. Chem., 40, 1347 (1997);
  • 12
    • 34250202592 scopus 로고    scopus 로고
    • TRPVl-antagonists: (a) L. A. Roberts, M. Connor, Recent Patents on CNS Drug Discovery, 1, 65 (2006); Ob) S. R. Fletcher, E. Mclver, S. Lewis, F. Burkamp, C. Leech, G. Mason, S. Boyce, D. Morrison, G. Richards, K. Sutton, A. B. Jones, Bioorg. Med. Chem. Lett., 16, 2872 (2006) and references therein; 11-ß-HSD-1 inhibitors: B. Sorensen, J. Rohde, J. Wang, S. Fung, K. Monzon, W. Chiou, L. Pan, X. Deng, D. Stolarik, E. U. Frevert, P. Jacobson, J. T. Link, Bioorg. Med. Chem. Lett., 16, 5958 (2006) and references therein
    • TRPVl-antagonists: (a) L. A. Roberts, M. Connor, Recent Patents on CNS Drug Discovery, 1, 65 (2006); Ob) S. R. Fletcher, E. Mclver, S. Lewis, F. Burkamp, C. Leech, G. Mason, S. Boyce, D. Morrison, G. Richards, K. Sutton, A. B. Jones, Bioorg. Med. Chem. Lett., 16, 2872 (2006) and references therein; 11-ß-HSD-1 inhibitors: B. Sorensen, J. Rohde, J. Wang, S. Fung, K. Monzon, W. Chiou, L. Pan, X. Deng, D. Stolarik, E. U. Frevert, P. Jacobson, J. T. Link, Bioorg. Med. Chem. Lett., 16, 5958 (2006) and references therein
  • 13
    • 84949805957 scopus 로고    scopus 로고
    • Fluorine in Organic Chemistry ed. by R. D. Chambers, Wiley, New York, 1973;
    • (a) "Fluorine in Organic Chemistry" ed. by R. D. Chambers, Wiley, New York, 1973;
  • 15
    • 73949151285 scopus 로고    scopus 로고
    • Biomedical Frontiers of Fluorine Chemistry eds. by I. Ojima, J. R. McCarthy, J. T. Welch, American Chemical Society, Washington DC, 1996
    • (c) "Biomedical Frontiers of Fluorine Chemistry" eds. by I. Ojima, J. R. McCarthy, J. T. Welch, American Chemical Society, Washington DC, 1996
  • 17
    • 73949147005 scopus 로고    scopus 로고
    • J. H. Simons, C. J. Lewis, J. Am. Chem. Soc., 60, 92 (1938);(c) W. R. Hasek, W. C. Smith, V. A. Engelhardt, ibid., 82, 543 (I960);
    • (b) J. H. Simons, C. J. Lewis, J. Am. Chem. Soc., 60, 92 (1938);(c) W. R. Hasek, W. C. Smith, V. A. Engelhardt, ibid., 82, 543 (I960);
  • 23
    • 73949142573 scopus 로고    scopus 로고
    • 32, 246 (1990); (e) L. D. Shustov, L. N. Nikolenko, T. M. Senchenkova, Zh. Obshch. Khim., 53, 103 (1983)
    • (d) 32, 246 (1990); (e) L. D. Shustov, L. N. Nikolenko, T. M. Senchenkova, Zh. Obshch. Khim., 53, 103 (1983)
  • 40
    • 73949150082 scopus 로고    scopus 로고
    • CF3-CH3PyH, CH3Py ⇄ 4-CF3-CH3Py, CH3PyH+ 2-CF 3-CH3PyH, CH3py ⇄ 2-CF 3-CH3Py, CH3PyH+ 4-CF 3CH3Py δH°, 13.2 kcal/mol; 2-CF 3CH3Py δ H°, 16.0 kcal/mol PM 3 2-CF3
    • 3
  • 45
    • 73949132583 scopus 로고    scopus 로고
    • 2008-214281
    • (c) 2008-214281
  • 61
    • 33748661487 scopus 로고    scopus 로고
    • M. Schlosser, Angew. Chem. Int. Ed., 45, 5432 (2006); (b) K. Uneyama, Organofluorine Chemistry, Blackwell Publishing, Oxford, UK (2006)
    • (a) M. Schlosser, Angew. Chem. Int. Ed., 45, 5432 (2006); (b) K. Uneyama, "Organofluorine Chemistry", Blackwell Publishing, Oxford, UK (2006)
  • 76
    • 30944441071 scopus 로고    scopus 로고
    • C. Brule, J.-P. Bouillon, E. Nicola!, C. Portella, Synthesis, 2006, 103;
    • (o) C. Brule, J.-P. Bouillon, E. Nicola!, C. Portella, Synthesis, 2006, 103;


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.