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Volumn 81, Issue 6, 2009, Pages 1093-1098

Androgen receptor antagonism and an insulin sensitizer block the advancement of vaginal opening by high-fat diet in mice

Author keywords

Androgen receptor; Androgens; High fat diet; Hypothalamus; Insulin; Metabolism; Neuroendocrine; Puberty

Indexed keywords

ANDROGEN; FLUTAMIDE; METFORMIN; ANDROGEN RECEPTOR; ANTIANDROGEN; ANTIDIABETIC AGENT; FATTY ACID; INSULIN; TESTOSTERONE;

EID: 73949110359     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.109.079301     Document Type: Article
Times cited : (26)

References (67)
  • 1
    • 0027538106 scopus 로고
    • Gonadotropin-releasing hormone pulse generator activity during pubertal transition in girls: Pulsatile and diurnal patterns of circulating gonadotropins
    • Apter D, Butzow TL, Laughlin GA, Yen SS. Gonadotropin-releasing hormone pulse generator activity during pubertal transition in girls: pulsatile and diurnal patterns of circulating gonadotropins. J Clin Endocrinol Metab 1993; 76:940-949.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 940-949
    • Apter, D.1    Butzow, T.L.2    Laughlin, G.A.3    Yen, S.S.4
  • 2
    • 0024384372 scopus 로고
    • In vivo release of luteinizing hormone releasing hormone increases with puberty in the female rhesus monkey
    • Watanabe G, Terasawa E. In vivo release of luteinizing hormone releasing hormone increases with puberty in the female rhesus monkey. Endocrinology 1989; 125:92-99.
    • (1989) Endocrinology , vol.125 , pp. 92-99
    • Watanabe, G.1    Terasawa, E.2
  • 3
    • 0018672238 scopus 로고
    • Endocrine mechanisms governing transition into adulthood: A marked decrease in inhibitory feedback action of estradiol on tonic secretion of luteinizing hormone in the lamb during puberty
    • Foster DL, Ryan KD. Endocrine mechanisms governing transition into adulthood: a marked decrease in inhibitory feedback action of estradiol on tonic secretion of luteinizing hormone in the lamb during puberty. Endocrinology 1979; 105:896-904.
    • (1979) Endocrinology , vol.105 , pp. 896-904
    • Foster, D.L.1    Ryan, K.D.2
  • 4
    • 16544370834 scopus 로고    scopus 로고
    • The neural basis of puberty and adolescence
    • Sisk CL, Foster DL. The neural basis of puberty and adolescence. Nat Neurosci 2004; 10:1040-1047.
    • (2004) Nat Neurosci , vol.10 , pp. 1040-1047
    • Sisk, C.L.1    Foster, D.L.2
  • 5
    • 0019809702 scopus 로고
    • The maturation of estradiol-negative feedback in female rats: Evidence that the resetting of the hypothalamic "gonadostat" does not precede the first preovulatory surge of gonadotropins
    • Andrews WW, Advis JP, Ojeda SR. The maturation of estradiol-negative feedback in female rats: evidence that the resetting of the hypothalamic "gonadostat" does not precede the first preovulatory surge of gonadotropins. Endocrinology 1981; 109:2022-2031.
    • (1981) Endocrinology , vol.109 , pp. 2022-2031
    • Andrews, W.W.1    Advis, J.P.2    Ojeda, S.R.3
  • 9
    • 75449148131 scopus 로고
    • Body weight and food intake as initiating factors for puberty in the rat
    • Kennedy GC, Mitra J. Body weight and food intake as initiating factors for puberty in the rat. J Physiol 1963; 166:408-418.
    • (1963) J Physiol , vol.166 , pp. 408-418
    • Kennedy, G.C.1    Mitra, J.2
  • 10
    • 0016149002 scopus 로고
    • Menstrual cycles: Fatness as a determinant of minimum weight for height necessary for their maintenance or onset
    • Frisch RE, McArthur JW. Menstrual cycles: fatness as a determinant of minimum weight for height necessary for their maintenance or onset. Science 1974; 185:949-951.
    • (1974) Science , vol.185 , pp. 949-951
    • Frisch, R.E.1    McArthur, J.W.2
  • 11
    • 0026721095 scopus 로고
    • Metabolic fuels and reproduction in female mammals
    • Wade GN, Schneider JE. Metabolic fuels and reproduction in female mammals. Neurosci Biobehav Rev 1992; 16:235-272.
    • (1992) Neurosci Biobehav Rev , vol.16 , pp. 235-272
    • Wade, G.N.1    Schneider, J.E.2
  • 13
    • 0025821988 scopus 로고
    • Suppression of puberty in rats by exercise: Effects on hormone levels and reversal with GnRH infusion
    • Manning JM, Bronson FH. Suppression of puberty in rats by exercise: effects on hormone levels and reversal with GnRH infusion. Am J Physiol 1991; 260:R717-R723.
    • (1991) Am J Physiol , vol.260
    • Manning, J.M.1    Bronson, F.H.2
  • 14
    • 0021921216 scopus 로고
    • Effect of restricted nutrition on puberty in the lamb: Patterns of tonic luteinizing hormone (LH) secretion and competency of the LH surge system
    • Foster DL, Olster DH. Effect of restricted nutrition on puberty in the lamb: patterns of tonic luteinizing hormone (LH) secretion and competency of the LH surge system. Endocrinology 1985; 116:375-381.
    • (1985) Endocrinology , vol.116 , pp. 375-381
    • Foster, D.L.1    Olster, D.H.2
  • 16
    • 0017576655 scopus 로고
    • Carcass components at first estrus of rats on high-fat and low-fat diets: Body water, protein, and fat
    • Frisch RE, Hegsted DM, Yoshinaga K. Carcass components at first estrus of rats on high-fat and low-fat diets: body water, protein, and fat. Proc Natl Acad Sci U S A 1977; 74:379-383.
    • (1977) Proc Natl Acad Sci U S A , vol.74 , pp. 379-383
    • Frisch, R.E.1    Hegsted, D.M.2    Yoshinaga, K.3
  • 17
    • 59449088244 scopus 로고    scopus 로고
    • Thelarche, pubarche, and menarche attainment in children with normal and elevated body mass index
    • Rosenfield RL, Lipton RB, Drum ML. Thelarche, pubarche, and menarche attainment in children with normal and elevated body mass index. Pediatrics 2009; 123:84-88.
    • (2009) Pediatrics , vol.123 , pp. 84-88
    • Rosenfield, R.L.1    Lipton, R.B.2    Drum, M.L.3
  • 18
    • 0037870484 scopus 로고    scopus 로고
    • The androgenic sex hormone profile is an essential feature of metabolic syndrome in premenopausal women: A controlled community-based study
    • Korhonen S, Hippelainen M, Vanhala M, Heinonen S, Niskanen L. The androgenic sex hormone profile is an essential feature of metabolic syndrome in premenopausal women: a controlled community-based study. Fertil Steril 2003; 79:1327-1334.
    • (2003) Fertil Steril , vol.79 , pp. 1327-1334
    • Korhonen, S.1    Hippelainen, M.2    Vanhala, M.3    Heinonen, S.4    Niskanen, L.5
  • 19
    • 32544457993 scopus 로고    scopus 로고
    • Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance
    • Coviello AD, Legro RS, Dunaif A. Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance. J Clin Endocrinol Metab 2006; 91:492-497.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 492-497
    • Coviello, A.D.1    Legro, R.S.2    Dunaif, A.3
  • 20
    • 33746032630 scopus 로고    scopus 로고
    • Obesity and polycystic ovary syndrome
    • Barber TM. Obesity and polycystic ovary syndrome. Clin Endocrinol (Oxf) 2006; 65:137-145.
    • (2006) Clin Endocrinol (Oxf) , vol.65 , pp. 137-145
    • Barber, T.M.1
  • 21
    • 33645959858 scopus 로고    scopus 로고
    • Effect of steroid milieu on gonadotropin- releasing hormone-1 neuron firing pattern and luteinizing hormone levels in male mice
    • Pielecka J, Moenter SM. Effect of steroid milieu on gonadotropin- releasing hormone-1 neuron firing pattern and luteinizing hormone levels in male mice. Biol Reprod 2006; 74:931-937.
    • (2006) Biol Reprod , vol.74 , pp. 931-937
    • Pielecka, J.1    Moenter, S.M.2
  • 22
    • 32644440014 scopus 로고    scopus 로고
    • Androgens increase gonadotropin-releasing hormone neuron firing activity in females and interfere with progesterone negative feedback
    • Pielecka J, Quaynor SD, Moenter SM. Androgens increase gonadotropin-releasing hormone neuron firing activity in females and interfere with progesterone negative feedback. Endocrinology 2006; 147:1474-1479.
    • (2006) Endocrinology , vol.147 , pp. 1474-1479
    • Pielecka, J.1    Quaynor, S.D.2    Moenter, S.M.3
  • 23
    • 0031765313 scopus 로고    scopus 로고
    • Polycystic ovary syndrome: Evidence for reduced sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone
    • Pastor CL, Griffin-Korf ML, Aloi JA, Evans WS, Marshall JC. Polycystic ovary syndrome: evidence for reduced sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone. J Clin Endocrinol Metab 1998; 83:582-590.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 582-590
    • Pastor, C.L.1    Griffin-Korf, M.L.2    Aloi, J.A.3    Evans, W.S.4    Marshall, J.C.5
  • 24
    • 0034523425 scopus 로고    scopus 로고
    • Polycystic ovarian syndrome: Evidence mat flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone
    • Eagleson CA, Gingrich MB, Pastor CL, Arora TK, Burt CM, Evans WS, Marshall JC. Polycystic ovarian syndrome: evidence mat flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone. J Clin Endocrinol Metab 2000; 85:4047-4052.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4047-4052
    • Eagleson, C.A.1    Gingrich, M.B.2    Pastor, C.L.3    Arora, T.K.4    Burt, C.M.5    Evans, W.S.6    Marshall, J.C.7
  • 25
    • 0031790832 scopus 로고    scopus 로고
    • Insulin stimulates testosterone biosynthesis by human thecal cells from women with polycystic ovary syndrome by activating its own receptor and using inositolglycan mediators as the signal transduction system
    • Nestler JE, Jakubowicz DJ, Falcon de Vargas A, Brik C, Quintero N, Medina F. Insulin stimulates testosterone biosynthesis by human thecal cells from women with polycystic ovary syndrome by activating its own receptor and using inositolglycan mediators as the signal transduction system. J Clin Endocrinol Metab 1998; 83:2001-2005.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2001-2005
    • Nestler, J.E.1    Jakubowicz, D.J.2    Falcon de Vargas, A.3    Brik, C.4    Quintero, N.5    Medina, F.6
  • 26
    • 0022647650 scopus 로고
    • Insulin stimulates androgen accumulation in incubations of ovarian stroma obtained from women with hyperandrogenism
    • Barbieri RL, Makris A, Randall RW, Daniels G, Kistner RW, Ryan KJ. Insulin stimulates androgen accumulation in incubations of ovarian stroma obtained from women with hyperandrogenism. J Clin Endocrinol Metab 1986; 62:904-910.
    • (1986) J Clin Endocrinol Metab , vol.62 , pp. 904-910
    • Barbieri, R.L.1    Makris, A.2    Randall, R.W.3    Daniels, G.4    Kistner, R.W.5    Ryan, K.J.6
  • 28
    • 56049116225 scopus 로고    scopus 로고
    • Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and {beta}-cell mass to age-related insulin resistance in rats
    • Matveyenko AV, Veldhuis JD, Butler PC. Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and {beta}-cell mass to age-related insulin resistance in rats. Am J Physiol Endocrinol Metab 2008; 295:E832-E841.
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Matveyenko, A.V.1    Veldhuis, J.D.2    Butler, P.C.3
  • 29
    • 0035112245 scopus 로고    scopus 로고
    • Neurobiological mechanisms of the onset of puberty in primates
    • Terasawa E, Fernandez DL. Neurobiological mechanisms of the onset of puberty in primates. Endocr Rev 2001; 22:111-151.
    • (2001) Endocr Rev , vol.22 , pp. 111-151
    • Terasawa, E.1    Fernandez, D.L.2
  • 32
    • 0000834943 scopus 로고
    • Advancement of puberty in the female rat by estrogen
    • Ramirez VD, Sawyer CH. Advancement of puberty in the female rat by estrogen. Endocrinology 1965; 76:1158-1168.
    • (1965) Endocrinology , vol.76 , pp. 1158-1168
    • Ramirez, V.D.1    Sawyer, C.H.2
  • 34
    • 0018872795 scopus 로고
    • The first proestrus in the female rat: Circulating steroid levels preceding and accompanying the preovulatory LH surge
    • Andrews WW, Advis JP, Ojeda SR. The first proestrus in the female rat: circulating steroid levels preceding and accompanying the preovulatory LH surge. Proc Soc Exp Biol Med 1980; 163:305-309.
    • (1980) Proc Soc Exp Biol Med , vol.163 , pp. 305-309
    • Andrews, W.W.1    Advis, J.P.2    Ojeda, S.R.3
  • 35
    • 0030948117 scopus 로고    scopus 로고
    • Ontogeny of steroidogenic enzyme gene expression in ovarian theca-interstitial cells in the rat: Regulation by a paracrine theca-differentiating factor prior to achieving luteinizing hormone responsiveness
    • Gelety TJ, Magoffin DA. Ontogeny of steroidogenic enzyme gene expression in ovarian theca-interstitial cells in the rat: regulation by a paracrine theca-differentiating factor prior to achieving luteinizing hormone responsiveness. Biol Reprod 1997; 56:938-945.
    • (1997) Biol Reprod , vol.56 , pp. 938-945
    • Gelety, T.J.1    Magoffin, D.A.2
  • 36
    • 10944261252 scopus 로고    scopus 로고
    • GABAergic integration of progesterone and androgen feedback to gonadotropin-releasing hormone neurons
    • Sullivan SD, Moenter SM. GABAergic integration of progesterone and androgen feedback to gonadotropin-releasing hormone neurons. Biol Reprod 2005; 72:33-41.
    • (2005) Biol Reprod , vol.72 , pp. 33-41
    • Sullivan, S.D.1    Moenter, S.M.2
  • 37
    • 0032984797 scopus 로고    scopus 로고
    • Androgen modulation of luteinizing hormone secretion by female rat gonadotropes
    • Turgeon JL, Waring DW. Androgen modulation of luteinizing hormone secretion by female rat gonadotropes. Endocrinology 1999; 140:1767-1774.
    • (1999) Endocrinology , vol.140 , pp. 1767-1774
    • Turgeon, J.L.1    Waring, D.W.2
  • 38
    • 0029919567 scopus 로고    scopus 로고
    • Testosterone is required for gonadotropin-releasing hormone stimulation of luteinizing hormone-beta messenger ribonucleic acid expression in female rats
    • Yasin M, Dalkin AC, Haisenleder DJ, Marshall JC Testosterone is required for gonadotropin-releasing hormone stimulation of luteinizing hormone-beta messenger ribonucleic acid expression in female rats. Endocrinology 1996; 137:1265-1271.
    • (1996) Endocrinology , vol.137 , pp. 1265-1271
    • Yasin, M.1    Dalkin, A.C.2    Haisenleder, D.J.3    Marshall, J.C.4
  • 39
    • 0030047593 scopus 로고    scopus 로고
    • Nutrition, insulin, and polycystic ovary syndrome
    • Franks S, Robinson S, Willis DS. Nutrition, insulin, and polycystic ovary syndrome. Rev Reprod 1996; 1:47-53.
    • (1996) Rev Reprod , vol.1 , pp. 47-53
    • Franks, S.1    Robinson, S.2    Willis, D.S.3
  • 40
    • 30344448576 scopus 로고    scopus 로고
    • PCOS/Troglitazone Study Group. Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome
    • Ehrmann DA, Liljenquist DR, Kasza K, Azziz R, Legro RS, Ghazzi MN; PCOS/Troglitazone Study Group. Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2006; 91:48-53.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 48-53
    • Ehrmann, D.A.1    Liljenquist, D.R.2    Kasza, K.3    Azziz, R.4    Legro, R.S.5    Ghazzi, M.N.6
  • 43
    • 33646410148 scopus 로고    scopus 로고
    • The association of obesity and hyperandrogenemia during the pubertal transition in girls: Obesity as a potential factor in the genesis of postpubertal hyperandrogenism
    • McCartney CR, Prendergast KA, Chhabra S, Eagleson CA, Yoo R, Chang RJ, Foster CM, Marshall JC The association of obesity and hyperandrogenemia during the pubertal transition in girls: obesity as a potential factor in the genesis of postpubertal hyperandrogenism. J Clin Endocrinol Metab 2006; 91:1714-1722.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1714-1722
    • McCartney, C.R.1    Prendergast, K.A.2    Chhabra, S.3    Eagleson, C.A.4    Yoo, R.5    Chang, R.J.6    Foster, C.M.7    Marshall, J.C.8
  • 44
    • 58149400588 scopus 로고    scopus 로고
    • Maturation of luteinizing hormone (gonadotropin-releasing hormone) secretion across puberty: Evidence for altered regulation in obese peripubertal girls
    • McCartney CR, Prendergast KA, Blank SK, Helm KD, Chhabra S, Marshall JC Maturation of luteinizing hormone (gonadotropin-releasing hormone) secretion across puberty: evidence for altered regulation in obese peripubertal girls. J Clin Endocrinol Metab 2009; 94:56-66.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 56-66
    • McCartney, C.R.1    Prendergast, K.A.2    Blank, S.K.3    Helm, K.D.4    Chhabra, S.5    Marshall, J.C.6
  • 45
    • 18844383658 scopus 로고    scopus 로고
    • Progesterone inhibition of the hypothalamic gonadotropin-releasing hormone pulse generator evidence for varied effects in hyperandrogenemic adolescent girls
    • Chhabra S, McCartney CR, Yoo RY, Eagleson CA, Chang RJ, Marshall JC. Progesterone inhibition of the hypothalamic gonadotropin-releasing hormone pulse generator evidence for varied effects in hyperandrogenemic adolescent girls. J Clin Endocrinol Metab 2005; 90:2810-2815.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2810-2815
    • Chhabra, S.1    McCartney, C.R.2    Yoo, R.Y.3    Eagleson, C.A.4    Chang, R.J.5    Marshall, J.C.6
  • 46
    • 0028356926 scopus 로고
    • Accelerated 24-hour luteinizing hormone pulsatile activity in adolescent girls with ovarian hyperandrogenism: Relevance to the developmental phase of polycystic ovarian syndrome
    • Apter D, Butzow T, Laughlin GA, Yen SS. Accelerated 24-hour luteinizing hormone pulsatile activity in adolescent girls with ovarian hyperandrogenism: relevance to the developmental phase of polycystic ovarian syndrome. J Clin Endocrinol Metab 1994; 79:119-125.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 119-125
    • Apter, D.1    Butzow, T.2    Laughlin, G.A.3    Yen, S.S.4
  • 47
    • 0027411120 scopus 로고
    • Regulation of androgen production in cultured human thecal cells by insulin-like growth factor I and insulin
    • Bergh C, Carlsson B, Olsson JH, Selleskog U, Hillensjo T. Regulation of androgen production in cultured human thecal cells by insulin-like growth factor I and insulin. Fertil Steril 1993; 59:323-331.
    • (1993) Fertil Steril , vol.59 , pp. 323-331
    • Bergh, C.1    Carlsson, B.2    Olsson, J.H.3    Selleskog, U.4    Hillensjo, T.5
  • 51
    • 33744956288 scopus 로고    scopus 로고
    • Metformin therapy during puberty delays menarche, prolongs pubertal growth, and augments adult height: A randomized study in low-birth-weight girls with early-normal onset of puberty
    • Ibanez L, Valls C, Ong K, Dunger DB, de Zegher F. Metformin therapy during puberty delays menarche, prolongs pubertal growth, and augments adult height: a randomized study in low-birth-weight girls with early-normal onset of puberty. J Clin Endocrinol Metab 2006; 91:2068-2073.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 2068-2073
    • Ibanez, L.1    Valls, C.2    Ong, K.3    Dunger, D.B.4    de Zegher, F.5
  • 53
  • 54
    • 0034892698 scopus 로고    scopus 로고
    • Metformin directly inhibits androgen production in human thecal cells
    • Attia GR, Rainey WE, Carr BR. Metformin directly inhibits androgen production in human thecal cells. Fertil Steril 2001; 76:517-524.
    • (2001) Fertil Steril , vol.76 , pp. 517-524
    • Attia, G.R.1    Rainey, W.E.2    Carr, B.R.3
  • 56
    • 33744989674 scopus 로고    scopus 로고
    • Chronic leptin infusion advances, and immunoneutralization of leptin postpones pubertal onset in normally fed and feed restricted female rats
    • Zeinoaldini S, Swarts JJ, Van de Heijning BJ. Chronic leptin infusion advances, and immunoneutralization of leptin postpones pubertal onset in normally fed and feed restricted female rats. Peptides 2006; 27:1652-1658.
    • (2006) Peptides , vol.27 , pp. 1652-1658
    • Zeinoaldini, S.1    Swarts, J.J.2    Van de Heijning, B.J.3
  • 57
    • 0031051499 scopus 로고    scopus 로고
    • Leptin treatment reduces the sterility of genetically obese ob/ob males
    • Mounzih K, Lu R, Chehab FF. Leptin treatment reduces the sterility of genetically obese ob/ob males. Endocrinology 1997; 138:1190-1193.
    • (1997) Endocrinology , vol.138 , pp. 1190-1193
    • Mounzih, K.1    Lu, R.2    Chehab, F.F.3
  • 58
    • 0034751338 scopus 로고    scopus 로고
    • Puberty in female mice is not associated with increases in either body fat or leptin
    • Branson FH. Puberty in female mice is not associated with increases in either body fat or leptin. Endocrinology 2001; 142:4758-4761.
    • (2001) Endocrinology , vol.142 , pp. 4758-4761
    • Branson, F.H.1
  • 61
    • 4644289298 scopus 로고    scopus 로고
    • Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide
    • Navarro VM, Castellano JM, Fernandez-Fernandez R, Barreiro ML, Roa J, Sanchez-Criado JE, Aguilar E, Dieguez C, Pinilla L, Tena-Sempere M. Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide. Endocrinology 2004; 145:4565-4574.
    • (2004) Endocrinology , vol.145 , pp. 4565-4574
    • Navarro, V.M.1    Castellano, J.M.2    Fernandez-Fernandez, R.3    Barreiro, M.L.4    Roa, J.5    Sanchez-Criado, J.E.6    Aguilar, E.7    Dieguez, C.8    Pinilla, L.9    Tena-Sempere, M.10
  • 62
    • 41549121999 scopus 로고    scopus 로고
    • Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol
    • Pielecka-Fortuna J, Chu Z, Moenter SM. Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol. Endocrinology 2008; 149:1979-1986.
    • (2008) Endocrinology , vol.149 , pp. 1979-1986
    • Pielecka-Fortuna, J.1    Chu, Z.2    Moenter, S.M.3
  • 65
    • 0024324195 scopus 로고
    • Availability of metabolic fuels controls estrous cyclicity of Syrian hamsters
    • Schneider JE, Wade GN. Availability of metabolic fuels controls estrous cyclicity of Syrian hamsters. Science 1989; 244:1326-1328.
    • (1989) Science , vol.244 , pp. 1326-1328
    • Schneider, J.E.1    Wade, G.N.2
  • 66
    • 0025292438 scopus 로고
    • Insulin-induced hypoglycemia stimulates corticotropin-releasing factor and arginine vasopressin secretion into hypophysial portal blood of conscious, unrestrained rams
    • Caraty A, Grino M, Locatelli A, Guillaume V, Boudouresque F, ConteDevolx B, Oliver C. Insulin-induced hypoglycemia stimulates corticotropin-releasing factor and arginine vasopressin secretion into hypophysial portal blood of conscious, unrestrained rams. J Clin Invest 1990; 85:1716-1721.
    • (1990) J Clin Invest , vol.85 , pp. 1716-1721
    • Caraty, A.1    Grino, M.2    Locatelli, A.3    Guillaume, V.4    Boudouresque, F.5    ConteDevolx, B.6    Oliver, C.7
  • 67
    • 0029996242 scopus 로고    scopus 로고
    • The insulin hypoglycemia-induced inhibition of gonadotropin-releasing hormone pulse generator activity in the rhesus monkey: Roles of vasopressin and corticotropin-releasing factor
    • Chen MD, Ordog T, O'Byrne KT, Goldsmith JR, Connaughton MA, Knobil E. The insulin hypoglycemia-induced inhibition of gonadotropin-releasing hormone pulse generator activity in the rhesus monkey: roles of vasopressin and corticotropin-releasing factor. Endocrinology 1996; 137:2012-2021.
    • (1996) Endocrinology , vol.137 , pp. 2012-2021
    • Chen, M.D.1    Ordog, T.2    O'Byrne, K.T.3    Goldsmith, J.R.4    Connaughton, M.A.5    Knobil, E.6


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