-
1
-
-
13844316734
-
Tyrosine kinase inhibitors and the dawn of molecular cancer therapeutics
-
Tibes R, Trent J, Kurzrock R. Tyrosine kinase inhibitors and the dawn of molecular cancer therapeutics. Ann Rev Pharamacol Toxicol 2005; 45:357-84.
-
(2005)
Ann Rev Pharamacol Toxicol
, vol.45
, pp. 357-384
-
-
Tibes, R.1
Trent, J.2
Kurzrock, R.3
-
2
-
-
0034722889
-
The EGF receptor family as targets for cancer therapy
-
Mendelsohn J, Baselga J. The EGF receptor family as targets for cancer therapy. Oncogene 2000; 19:6550-65.
-
(2000)
Oncogene
, vol.19
, pp. 6550-6565
-
-
Mendelsohn, J.1
Baselga, J.2
-
3
-
-
0030030072
-
ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: Implications for breast cancer
-
Karunagaran D, Tzahar E, Beerli RR, Chen X, Graus-Porta D, Ratzkin BJ, et al. ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer. EMBO J 1996; 15:254-64.
-
(1996)
EMBO J
, vol.15
, pp. 254-264
-
-
Karunagaran, D.1
Tzahar, E.2
Beerli, R.R.3
Chen, X.4
Graus-Porta, D.5
Ratzkin, B.J.6
-
4
-
-
0026174552
-
Characterization of an anti-p185HER2 monoclonal antibody that stimulates receptor function and inhibits tumor cell growth
-
Sarup JC, Johnson RM, King KL, Fendly BM, Lipari MT, Napier MA, et al. Characterization of an anti-p185HER2 monoclonal antibody that stimulates receptor function and inhibits tumor cell growth. Growth Regul 1991; 1:72-82.
-
(1991)
Growth Regul
, vol.1
, pp. 72-82
-
-
Sarup, J.C.1
Johnson, R.M.2
King, K.L.3
Fendly, B.M.4
Lipari, M.T.5
Napier, M.A.6
-
5
-
-
33846709211
-
Lapatinib: A dual inhibitor of EGFR and HER2 tyrosine kinase activity
-
Montemurro F, Balabrega G, Aglietta M. Lapatinib: a dual inhibitor of EGFR and HER2 tyrosine kinase activity. Expert Opin Biol Ther 2007; 2:257-68.
-
(2007)
Expert Opin Biol Ther
, vol.2
, pp. 257-268
-
-
Montemurro, F.1
Balabrega, G.2
Aglietta, M.3
-
6
-
-
33846202907
-
Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs
-
Ono M, Kuwano M. Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs. Clin. Cancer Res 2006; 12:7242-51.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 7242-7251
-
-
Ono, M.1
Kuwano, M.2
-
7
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, Tracy S, Greulich H, Gabriel S, et al. EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science 2004; 304:1497-500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
-
8
-
-
25144521731
-
Tracer development and hybrid imaging
-
Yang DJ, Kim EE. Tracer development and hybrid imaging. Eur J Med Mol Imaging 2005; 32:1001-2.
-
(2005)
Eur J Med Mol Imaging
, vol.32
, pp. 1001-1002
-
-
Yang, D.J.1
Kim, E.E.2
-
9
-
-
0021799571
-
Structure and localization of genes encoding aberrant and normal epidermal growth factor receptor RNAs from A431 human carcinoma cells
-
Merlino GT, Ishii S, Whang-Peng J, Knutsen T, Xu YH, Clark AJ, et al. Structure and localization of genes encoding aberrant and normal epidermal growth factor receptor RNAs from A431 human carcinoma cells. Mol Cell Biol 1985; 5:1722-34.
-
(1985)
Mol Cell Biol
, vol.5
, pp. 1722-1734
-
-
Merlino, G.T.1
Ishii, S.2
Whang-Peng, J.3
Knutsen, T.4
Xu, Y.H.5
Clark, A.J.6
-
10
-
-
33845381862
-
Tumor inhibitory effect of gefitinib (ZD1839, Iressa) and taxane combination therapy in EGFR overexpressing breast cancer cell lines (MCF7/ADR, MDA-MB-231)
-
Takabatake D, Fujita T, Shien T, Kawasaki K, Taira N, Yoshitomi S, et al. Tumor inhibitory effect of gefitinib (ZD1839, Iressa) and taxane combination therapy in EGFR overexpressing breast cancer cell lines (MCF7/ADR, MDA-MB-231). Int J Cancer 2007;120:181-8.
-
(2007)
Int J Cancer
, vol.120
, pp. 181-188
-
-
Takabatake, D.1
Fujita, T.2
Shien, T.3
Kawasaki, K.4
Taira, N.5
Yoshitomi, S.6
-
11
-
-
0036848833
-
Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (IRESSA)
-
Heimberger AB, Learn CA, Archer GE, McLendon RE, Chewning TA, Tuck FL, et al. Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (IRESSA). Clin Cancer Res 2002; 8:3496-502.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3496-3502
-
-
Heimberger, A.B.1
Learn, C.A.2
Archer, G.E.3
McLendon, R.E.4
Chewning, T.A.5
Tuck, F.L.6
-
12
-
-
0035892346
-
IRESSA), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the growth of EGFR-positive cancer cell lines with or without erbB2 overexpression
-
Anderson NG, Ahmad T, Chan K, Dobson R, Bundred NJ. ZD1839 (IRESSA), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the growth of EGFR-positive cancer cell lines with or without erbB2 overexpression. Int J Cancer 2001; 94:774-82.
-
(1839)
Int J Cancer 2001
, vol.94
, pp. 774-782
-
-
Anderson, N.G.1
Ahmad, T.2
Chan, K.3
Dobson, R.4
Bundred, N.Z.5
-
13
-
-
35648953299
-
-
Cragg MS, Kuroda J, Puthalakath H, Huang DCS, Strasser A. Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics. PLoS Medicine 2007; 4:1681-90.
-
Cragg MS, Kuroda J, Puthalakath H, Huang DCS, Strasser A. Gefitinib-induced killing of NSCLC cell lines expressing mutant EGFR requires BIM and can be enhanced by BH3 mimetics. PLoS Medicine 2007; 4:1681-90.
-
-
-
-
14
-
-
0029043888
-
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
-
Vermes I, Haanen C, Steffens-Nakken K, Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 1995; 184:39-51.
-
(1995)
J Immunol Methods
, vol.184
, pp. 39-51
-
-
Vermes, I.1
Haanen, C.2
Steffens-Nakken, K.3
Reutelingsperger, C.4
-
15
-
-
0001927481
-
Dimerization of an intermediate during the sodium in liquid ammonia reduction of 1-thiazolidine-4-caroxylic acid
-
Blondeau P, Berse C, Grave ID. Dimerization of an intermediate during the sodium in liquid ammonia reduction of 1-thiazolidine-4-caroxylic acid. Can J Chem 1967; 45:49-52.
-
(1967)
Can J Chem
, vol.45
, pp. 49-52
-
-
Blondeau, P.1
Berse, C.2
Grave, I.D.3
-
16
-
-
0027517519
-
First experience in healthy volunteers with Tc-99m-L-ethylenedicysteine, a new renal imaging agent
-
Van Nerom CG, Bormans GM, De Roo MJ, Verbruggen AM. First experience in healthy volunteers with Tc-99m-L-ethylenedicysteine, a new renal imaging agent. Eur J Nuc Med 1993; 20:738-46.
-
(1993)
Eur J Nuc Med
, vol.20
, pp. 738-746
-
-
Van Nerom, C.G.1
Bormans, G.M.2
De Roo, M.J.3
Verbruggen, A.M.4
-
17
-
-
0028170233
-
Usefulness of Tc-99m-N,N-ethylene-1- dicysteine complex for dynamic kidney investigations
-
Surma MJ, Wiewiora J, Liniecki J. Usefulness of Tc-99m-N,N-ethylene-1- dicysteine complex for dynamic kidney investigations. Nucl Med Commun 1994; 15:628-35.
-
(1994)
Nucl Med Commun
, vol.15
, pp. 628-635
-
-
Surma, M.J.1
Wiewiora, J.2
Liniecki, J.3
-
18
-
-
0032216520
-
99mTc-ethylenedicysteine-folate: A new tumor imaging agent. Synthesis, labeling and evaluation in animals
-
99mTc-ethylenedicysteine-folate: a new tumor imaging agent. Synthesis, labeling and evaluation in animals. Cancer Biother Radiopharm 1998; 13:427-35.
-
(1998)
Cancer Biother Radiopharm
, vol.13
, pp. 427-435
-
-
Ilgan, S.1
Yang, D.J.2
Higuchi, T.3
Zareneyrizi, F.4
Bayhan, H.5
Yu, D.6
-
21
-
-
20644463935
-
125I]iodo-2′-deoxyuridine in metastatic lung cancer: Radiopharmaceutical formulation affects targeting
-
125I]iodo-2′-deoxyuridine in metastatic lung cancer: radiopharmaceutical formulation affects targeting. J Nucl Med 2005; 46:800-6.
-
(2005)
J Nucl Med
, vol.46
, pp. 800-806
-
-
Semnani, E.S.1
Wang, K.2
Adelstein, S.J.3
Kassis, A.I.4
-
24
-
-
0022208545
-
Carbon-11 choline: Synthesis, purification and brain uptake inhibition by 2-dimethylaminoethanol
-
Rosen MA, Jones RM, Yano Y, Budinger TF. Carbon-11 choline: synthesis, purification and brain uptake inhibition by 2-dimethylaminoethanol. J Nucl Med 1985; 26:1424-8.
-
(1985)
J Nucl Med
, vol.26
, pp. 1424-1428
-
-
Rosen, M.A.1
Jones, R.M.2
Yano, Y.3
Budinger, T.F.4
-
25
-
-
0003074186
-
Technetium-99m HYNIC-annexin V: A potential radiopharmaceutical for the in-vivo detection of apoptosis
-
Ohtsuki K, Akashi K, Aoka Y, Blankenberg FG, Kopiwoda S, Tait JF, et al. Technetium-99m HYNIC-annexin V: a potential radiopharmaceutical for the in-vivo detection of apoptosis. Eur J Nucl Med 1999; 26:1251-8.
-
(1999)
Eur J Nucl Med
, vol.26
, pp. 1251-1258
-
-
Ohtsuki, K.1
Akashi, K.2
Aoka, Y.3
Blankenberg, F.G.4
Kopiwoda, S.5
Tait, J.F.6
-
26
-
-
0026891522
-
Cyclotrons and positron emission tomography radiopharmaceuticals for clinical imaging
-
Saha GB, MacIntyre WJ, Go RT. Cyclotrons and positron emission tomography radiopharmaceuticals for clinical imaging. Semin Nucl Med 1992; 22:150-61.
-
(1992)
Semin Nucl Med
, vol.22
, pp. 150-161
-
-
Saha, G.B.1
MacIntyre, W.J.2
Go, R.T.3
-
28
-
-
0027517519
-
First experience in healthy volunteers with technetium-99m L,L-ethylenedicysteine, a new renal imaging agent
-
Van Nerom CG, Bormans GM, De Roo MJ, Verbruggen AM. First experience in healthy volunteers with technetium-99m L,L-ethylenedicysteine, a new renal imaging agent. Eur J Nucl Med 1993; 20:738-46.
-
(1993)
Eur J Nucl Med
, vol.20
, pp. 738-746
-
-
Van Nerom, C.G.1
Bormans, G.M.2
De Roo, M.J.3
Verbruggen, A.M.4
-
29
-
-
0034005489
-
Kinetic characterization of CMD-A2-Gd-DOTA as an intravascular contrast agent for myocardial perfusion measurement with MRI
-
Canet EP, Casalic C, Desenfant A, An MY, Corot C, Obadia JF, et al. Kinetic characterization of CMD-A2-Gd-DOTA as an intravascular contrast agent for myocardial perfusion measurement with MRI. Magn Reson Med 2000; 43:403-9.
-
(2000)
Magn Reson Med
, vol.43
, pp. 403-409
-
-
Canet, E.P.1
Casalic, C.2
Desenfant, A.3
An, M.Y.4
Corot, C.5
Obadia, J.F.6
-
30
-
-
0028314625
-
Functional evaluation of normal and ischemic kidney by means of gadolinium-DOTA enhanced TurboFLASH MR imaging: A preliminary comparison with 99Tc-MAG3 dynamic scintigraphy
-
Laissy JP, Faraggi M, Lebtahi R, Soyer P, Brillet G, Méry JP, et al. Functional evaluation of normal and ischemic kidney by means of gadolinium-DOTA enhanced TurboFLASH MR imaging: a preliminary comparison with 99Tc-MAG3 dynamic scintigraphy. Magn Reson Imaging 1994; 12:413-9.
-
(1994)
Magn Reson Imaging
, vol.12
, pp. 413-419
-
-
Laissy, J.P.1
Faraggi, M.2
Lebtahi, R.3
Soyer, P.4
Brillet, G.5
Méry, J.P.6
-
31
-
-
0032127361
-
Technetium-99m methoxyisobutylisonitrile chest imaging of small cell lung carcinoma: Relation to patient prognosis and chemotherapy response - a preliminary report
-
Kao CH, ChangLai SP, Chieng PU, Yen TC. Technetium-99m methoxyisobutylisonitrile chest imaging of small cell lung carcinoma: relation to patient prognosis and chemotherapy response - a preliminary report. Cancer 1998; 83:64-8.
-
(1998)
Cancer
, vol.83
, pp. 64-68
-
-
Kao, C.H.1
ChangLai, S.P.2
Chieng, P.U.3
Yen, T.C.4
-
32
-
-
0041383911
-
Using Tc-99m DMSA renal cortex scan to detect renal damage in women with type 2 diabetes
-
Wu HC, Chang CH, Lai MM, Lin CC, Lee CC, Kao A. Using Tc-99m DMSA renal cortex scan to detect renal damage in women with type 2 diabetes. J Diabetes Complications 2003;17:297-300.
-
(2003)
J Diabetes Complications
, vol.17
, pp. 297-300
-
-
Wu, H.C.1
Chang, C.H.2
Lai, M.M.3
Lin, C.C.4
Lee, C.C.5
Kao, A.6
-
33
-
-
0001927481
-
Dimerization of an intermediate during the sodium in liquid ammonia reduction of L-thiazolidine-4-carboxylic acid
-
Blondeau P, Berse C, Gravel D. Dimerization of an intermediate during the sodium in liquid ammonia reduction of L-thiazolidine-4-carboxylic acid. Can J Chem 1967; 45:49-52.
-
(1967)
Can J Chem
, vol.45
, pp. 49-52
-
-
Blondeau, P.1
Berse, C.2
Gravel, D.3
-
34
-
-
0000031505
-
The action of formaldehyde upon cysteine
-
Ratner S, Clarke HT. The action of formaldehyde upon cysteine. J Am Chem Soc 1937; 59:200-6.
-
(1937)
J Am Chem Soc
, vol.59
, pp. 200-206
-
-
Ratner, S.1
Clarke, H.T.2
-
35
-
-
24044512334
-
99mTc-EC-guanine: Synthesis, biodistribution and tumor imaging in animals
-
99mTc-EC-guanine: synthesis, biodistribution and tumor imaging in animals. Pharmaceutical Research 2005; 22:1471-9.
-
(2005)
Pharmaceutical Research
, vol.22
, pp. 1471-1479
-
-
Yang, D.J.1
Ozaki, K.2
Oh, C.S.3
Azhdarinia, A.4
Yang, T.5
Ito, M.6
-
40
-
-
59649083434
-
Labeling internalizing anti-epidermal growth factor receptor variant III monoclonal antibody with (177)Lu: In vitro comparison of acyclic and macrocyclic ligands
-
Hens M, Vaidyanathan G, Welsh P, Zalutsky MR. Labeling internalizing anti-epidermal growth factor receptor variant III monoclonal antibody with (177)Lu: in vitro comparison of acyclic and macrocyclic ligands. Nucl Med Biol 2009; 36:117-28.
-
(2009)
Nucl Med Biol
, vol.36
, pp. 117-128
-
-
Hens, M.1
Vaidyanathan, G.2
Welsh, P.3
Zalutsky, M.R.4
-
44
-
-
33846185483
-
-
Gong J, Yang D, Kohanim S, Humphreys R, Broemeling L, Kurzrock R. Novel in vivo imaging shows upregulation of death receptors by paclitaxel and correlates with enhanced antitumor effects of receptor agonist antibodies. Mol Cancer Ther 2006; 5:2991-3000.
-
Gong J, Yang D, Kohanim S, Humphreys R, Broemeling L, Kurzrock R. Novel in vivo imaging shows upregulation of death receptors by paclitaxel and correlates with enhanced antitumor effects of receptor agonist antibodies. Mol Cancer Ther 2006; 5:2991-3000.
-
-
-
-
45
-
-
0037109014
-
ZD1839 (Iressa): An orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy
-
Wakeling AE, Guy SP, Woodburn JR, Ashton SE, Curry BJ, Barker AJ, et al. ZD1839 (Iressa): An orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Res 2002; 62:5749-54.
-
(2002)
Cancer Res
, vol.62
, pp. 5749-5754
-
-
Wakeling, A.E.1
Guy, S.P.2
Woodburn, J.R.3
Ashton, S.E.4
Curry, B.J.5
Barker, A.J.6
-
46
-
-
33845724757
-
Resistance to gefitinib
-
Uramoto H, Sugio K, Oyama T, Sugaya M, Hanagiri T, Yasumoto K. Resistance to gefitinib. Int J Clin Oncol 2006; 11:487-91.
-
(2006)
Int J Clin Oncol
, vol.11
, pp. 487-491
-
-
Uramoto, H.1
Sugio, K.2
Oyama, T.3
Sugaya, M.4
Hanagiri, T.5
Yasumoto, K.6
-
47
-
-
2342471392
-
Activating mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al. Activating mutations in lung cancer: correlation with clinical response to gefitinib therapy. N Engl J Med 2004; 350:2129-39.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
-
49
-
-
25444439808
-
Combined radioimmunotherpy and chemotherapy of breast tumor with Y-90-labeled anti-HER2 and anti-CEA antibodies with taxol
-
Crow DM, Williams L, Colcher D, Wong JY, Raubitschek A, Shively JE. Combined radioimmunotherpy and chemotherapy of breast tumor with Y-90-labeled anti-HER2 and anti-CEA antibodies with taxol. Bioconjugate Chem 2005; 16:1117-25.
-
(2005)
Bioconjugate Chem
, vol.16
, pp. 1117-1125
-
-
Crow, D.M.1
Williams, L.2
Colcher, D.3
Wong, J.Y.4
Raubitschek, A.5
Shively, J.E.6
|