Improved triglyceride transesterification by circular permuted Candida antarctica lipase B

Biotechnology and Bioengineering

Volumn 105, Issue 1, 2010, Pages 44-50

  Yu, Ying ^a   Lutz, Stefan ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

Biodiesel; Candida antarctica lipase B; Circular permutation; Enzyme engineering; Transesterification

Indexed keywords

1-BUTANOL; ACYL ACCEPTOR; CANDIDA ANTARCTICA LIPASE B; CATALYTIC ACTIVITY; CATALYTIC CYCLES; CIRCULAR PERMUTATION; DIFFERENT SUBSTRATES; ENZYME ENGINEERING; ETHYL ACETATES; INTERESTERIFICATION; POTENTIAL APPLICATIONS; RATE DETERMINING STEP; WILD TYPES;

BIODIESEL; ENZYMES; ESTERS; ISOMERS; TRANSESTERIFICATION;

LIPASES;

ACETIC ACID ETHYL ESTER; ALCOHOL; BUTANOL; CP283 ENZYME; ESTER; FUNGAL ENZYME; LIPASE B; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VEGETABLE OIL;

ARTICLE; CANDIDA ANTARCTICA; CATALYSIS; CONTROLLED STUDY; ENZYME SUBSTRATE; INTERESTERIFICATION; KINETICS; NONHUMAN; TRANSESTERIFICATION;

CANDIDA; CATALYSIS; ENZYMES, IMMOBILIZED; ESTERIFICATION; KINETICS; LIPASE; MOLECULAR STRUCTURE; TRIGLYCERIDES;

CANDIDA ANTARCTICA;

EID: 73949098126     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22471     Document Type: Article

References (16)

1. Akoh CC, Chang SW, Lee GC, Shaw JF. 2007. Enzymatic approach to biodiesel production. J Agric Food Chem 55(22):8995-9005.
2. Berglund P. 2001. Controlling lipase enantioselectivity for organic synthesis. Biomol Eng 18(1):13-22.
3. Bornscheuer UT, Kazlauskas RJ. 2006. Hydrolases in organic synthesis: Regio- and stereoselective biotransformations. Weinheim: Wiley-VCH. xii, 355 p.
4. Chen JW, Wu WT. 2003. Regeneration of immobilized Candida antarctica lipase for transesterification. J Biosci Bioeng 95(5):466-469.
5. Du W, Xu YY, Liu DH, Zeng J. 2004. Comparative study on lipase-catalyzed transformation of soybean oil for biodiesel production with different acyl acceptors. J Mol Catal B: Enzym 30(3-4):125-129.
6. Fjerbaek L, Christensen KV, Norddahl B. 2009. A review of the current state of biodiesel production using enzymatic transesterification. Biotechnol Bioeng 102(5):1298-1315.
7. Hernandez-Martin E, Otero C. 2008. Different enzyme requirements for the synthesis of biodiesel: Novozym 435 and Lipozyme TL IM. Bioresour Technol 99(2):277-286.
8. Jegannathan KR, Abang S, Poncelet D, Chan ES, Ravindra P. 2008. Production of biodiesel using immobilized lipase-a critical review. Crit Rev Biotechnol 28(4):253-264.
9. Modi MK, Reddy JR, Rao BV, Prasad RB. 2007. Lipase-mediated conversion of vegetable oils into biodiesel using ethyl acetate as acyl acceptor. Bioresour Technol 98(6):1260-1264.
10. Qian Z, Lutz S. 2005. Improving the catalytic activity of Candida antarctica lipase B by circular permutation. J Am Chem Soc 127(39):13466-13467.
11. Qian Z, Fields CJ, Lutz S. 2007a. Investigating the structural and functional consequences of circular permutation on lipase B from Candida antarctica. Chembiochem 8(16):1989-1996.
12. Qian Z, Fields CJ, Yu Y, Lutz S. 2007b. Recent progress in engineering alpha/beta hydrolase-fold family members. Biotechnol J 2(2):192-200.
13. Qian Z, Horton JR, Cheng X, Lutz S. 2009. Structural redesign of lipase B from Candida antarctica by circular permutation and incremental truncation. J Mol Biol (manuscript under revision).
14. Ranganathan SV, Narasimhan SL, Muthukumar K. 2008. An overview of enzymatic production of biodiesel. Bioresour Technol 99(10):3975-3981.
15. Salameh M, Wiegel J. 2007. Lipases from extremophiles and potential for industrial applications. Adv Appl Microbiol 61:253-283.
16. Xu YY, Du W, Liu DH. 2005. Study on the kinetics of enzymatic interesterification of triglycerides for biodiesel production with methyl acetate as the acyl acceptor. J Mol Catal B: Enzym 32(5-6):241-245.