Use of real-time FT-IR monitoring of a pharmaceutical compound under stress atmospheric conditions to characterize Its solid-state degradation kinetics

International Journal of Chemical Kinetics

Volumn 42, Issue 1, 2010, Pages 25-36

  Skrdla, Peter J ^a   Harrington , Chandra ^a,b   Lin , Zhihao ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATMOSPHERIC CONDITIONS; CONVERSION RATES; DEGRADATION KINETICS; DENUCLEATION; DISPERSIVE KINETICS; EXPERIMENTAL CONDITIONS; FIRST-ORDER; HIGH QUALITY; HIGH TEMPERATURE; KINETIC MODELS; PHARMACEUTICAL COMPOUNDS; REAL-TIME FT-IR; STORAGE CONDITION;

ATMOSPHERIC HUMIDITY; FINITE DIFFERENCE METHOD; HYDROLYSIS; KINETIC THEORY;

DEGRADATION;

EID: 73849142836     PISSN: 05388066     EISSN: 10974601     Source Type: Journal    
DOI: 10.1002/kin.20458     Document Type: Article

References (23)

1. www.ich.org
2. Skrdla, P. J.; Abrahim, A.; Wu, Y. J Pharm Biomed Anal 2006, 41, 883.
3. Skrdla, P. J. J Phys Chem A 2007, 111, 11809.
4. Skrdla, P. J. J Phys Chem A 2007, 111, 4248.
5. Skrdla, P. J. J Phys Chem A 2006, 110, 11494.
6. Skrdla, P. J.; Robertson, R. T. J Phys Chem B 2005, 109, 10611.
7. Vyazovkin, S. J Thermal Anal Cal 2006, 83, 45.
8. Skrdla, P. J.; Robertson, R. T. Thermochim Acta 2007, 453, 14.
9. Khawam, A.; Flannagan, D. R. J Phys Chem B 2006, 110, 17315.
10. O'Brien, L. E.; Timmins, P.; Williams, A. C.; York, P. J Pharm Biomed Anal 2004, 36, 335.
11. Fait, M. J. G.; Lunk, H.-J.; Feist, M.; Schneider, M.; Dann, J. N.; Frisk, T. A. Thermochim Acta 2008, 469, 12.
12. Deb, S. K.; Manghnani, M. H.; Ross, K.; Livingston, R. A.; Monteiro, P. J. M. Phys Chem Miner 2003, 30, 31.
13. Bansal, G.; Singh, M.; Jindal, K. C. Chromatographia 2007, 66, 751.
14. Darrington, R. T.; Jiao, J. J Pharm Sci 2004, 93, 838.
15. Tan, W. J.; Widjaja, E. J Pharm Sci 2008, 97, 3379.
16. Magari, R. T.; Munoz-Antoni, I.; Baker, J.; Flagler, D. J. J Clin Lab Anal 2004, 18, 159.
17. Waterman, K. C.; Carella, A. J.; Gumkowski, M. J.; Lukulay, P.; MacDonald, B. C.; Roy, M. C.; Shamblin, S. L. Pharm Res 2007, 24, 780.
18. Skrdla, P. J. J Phys Chem A 2004, 108, 6709.
19. Skrdla, P. J. J Pharm Biomed Anal 2007, 45, 251.
20. Plonka, A. Sci Rev 2000, 25, 109.
21. Plonka, A. Annu Rep Prog Chem Sect C 2001, 97, 91.
22. Vyazovkin, S. Anal Chem 2008, 80, 4301.
23. Skrdla, P. J. J Pharm Sci 2007, 96, 2107.